The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Erythroid Transcription Factor GATA-1, subunit A
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 8: estrogen-related receptor gamma isoform X1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 38 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
78 O08580 (/IPI) O08580 (/IPI) P11474 (/IPI) P11474 (/IPI) P11474 (/IPI) P11474 (/IPI) P11474 (/IPI) P62508 (/IPI) P62508 (/IPI) P62508 (/IPI)
(68 more)
AF-2 domain binding GO:0050682
Interacting selectively and non-covalently with the AF-2 domain of a protein, a highly conserved ligand-dependent transactivation domain which is essential for receptor-mediated transcriptional activation.
70 P62508 (/ISS) P62508 (/ISS) P62508 (/ISS) P62508 (/ISS) P62508 (/ISS) P62508 (/ISS) P62508 (/ISS) P62508 (/ISS) P62508 (/ISS) P62508 (/ISS)
(60 more)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
41 O95718 (/ISA) P11474 (/ISA) P11474 (/ISA) P11474 (/ISA) P11474 (/ISA) P11474 (/ISA) P62508 (/ISA) P62508 (/ISA) P62508 (/ISA) P62508 (/ISA)
(31 more)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
41 O95718 (/ISM) P11474 (/ISM) P11474 (/ISM) P11474 (/ISM) P11474 (/ISM) P11474 (/ISM) P62508 (/ISM) P62508 (/ISM) P62508 (/ISM) P62508 (/ISM)
(31 more)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
41 O95718 (/NAS) P11474 (/NAS) P11474 (/NAS) P11474 (/NAS) P11474 (/NAS) P11474 (/NAS) P62508 (/NAS) P62508 (/NAS) P62508 (/NAS) P62508 (/NAS)
(31 more)
DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to activate or increase transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
38 O08580 (/IDA) O08580 (/IDA) P62509 (/IDA) P62509 (/IDA) P62509 (/IDA) P62509 (/IDA) P62509 (/IDA) P62509 (/IDA) P62509 (/IDA) P62509 (/IDA)
(28 more)
Nuclear receptor activity GO:0004879
Combining with a signal and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II.
37 P62509 (/NAS) P62509 (/NAS) P62509 (/NAS) P62509 (/NAS) P62509 (/NAS) P62509 (/NAS) P62509 (/NAS) P62509 (/NAS) P62509 (/NAS) P62509 (/NAS)
(27 more)
RNA polymerase II regulatory region sequence-specific DNA binding GO:0000977
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase II.
35 P62509 (/IDA) P62509 (/IDA) P62509 (/IDA) P62509 (/IDA) P62509 (/IDA) P62509 (/IDA) P62509 (/IDA) P62509 (/IDA) P62509 (/IDA) P62509 (/IDA)
(25 more)
DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to activate or increase transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
35 P62509 (/IMP) P62509 (/IMP) P62509 (/IMP) P62509 (/IMP) P62509 (/IMP) P62509 (/IMP) P62509 (/IMP) P62509 (/IMP) P62509 (/IMP) P62509 (/IMP)
(25 more)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
35 P62509 (/NAS) P62509 (/NAS) P62509 (/NAS) P62509 (/NAS) P62509 (/NAS) P62509 (/NAS) P62509 (/NAS) P62509 (/NAS) P62509 (/NAS) P62509 (/NAS)
(25 more)
Calmodulin binding GO:0005516
Interacting selectively and non-covalently with calmodulin, a calcium-binding protein with many roles, both in the calcium-bound and calcium-free states.
35 P62509 (/NAS) P62509 (/NAS) P62509 (/NAS) P62509 (/NAS) P62509 (/NAS) P62509 (/NAS) P62509 (/NAS) P62509 (/NAS) P62509 (/NAS) P62509 (/NAS)
(25 more)
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
13 F1QQS8 (/IDA) F6PD98 (/IDA) O08580 (/IDA) O08580 (/IDA) P11474 (/IDA) P11474 (/IDA) P11474 (/IDA) P11474 (/IDA) P11474 (/IDA) Q61539 (/IDA)
(3 more)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
9 O95718 (/IDA) P11474 (/IDA) P11474 (/IDA) P11474 (/IDA) P11474 (/IDA) P11474 (/IDA) Q5QJV7 (/IDA) Q5QJV7 (/IDA) Q61539 (/IDA)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
7 O08580 (/ISS) O08580 (/ISS) P11475 (/ISS) Q5QJV7 (/ISS) Q5QJV7 (/ISS) Q61539 (/ISS) Q6QMY5 (/ISS)
Nuclear receptor activity GO:0004879
Combining with a signal and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II.
6 O95718 (/TAS) P11474 (/TAS) P11474 (/TAS) P11474 (/TAS) P11474 (/TAS) P11474 (/TAS)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
5 P11474 (/TAS) P11474 (/TAS) P11474 (/TAS) P11474 (/TAS) P11474 (/TAS)
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
5 O95718 (/ISS) P11475 (/ISS) Q5QJV7 (/ISS) Q5QJV7 (/ISS) Q6QMY5 (/ISS)
Protein domain specific binding GO:0019904
Interacting selectively and non-covalently with a specific domain of a protein.
5 P11474 (/IPI) P11474 (/IPI) P11474 (/IPI) P11474 (/IPI) P11474 (/IPI)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
3 O95718 (/ISS) P11475 (/ISS) Q61539 (/ISS)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
3 O08580 (/ISO) O08580 (/ISO) Q61539 (/ISO)
RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978
Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in the proximal promoter of a gene transcribed by RNA polymerase II. The proximal promoter is in cis with and relatively close to the core promoter.
2 O08580 (/IDA) O08580 (/IDA)
RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978
Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in the proximal promoter of a gene transcribed by RNA polymerase II. The proximal promoter is in cis with and relatively close to the core promoter.
2 O95718 (/ISS) P11475 (/ISS)
RNA polymerase II distal enhancer sequence-specific DNA binding GO:0000980
Interacting selectively and non-covalently with a RNA polymerase II (Pol II) distal enhancer. In mammalian cells, enhancers are distal sequences that increase the utilization of some promoters, and can function in either orientation and in any location (upstream or downstream) relative to the core promoter.
2 O95718 (/ISS) P11475 (/ISS)
RNA polymerase II complex binding GO:0000993
Interacting selectively and non-covalently with RNA polymerase II core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of twelve subunits.
2 O95718 (/ISS) P11475 (/ISS)
Enhancer sequence-specific DNA binding GO:0001158
Interacting selectively and non-covalently with a specific sequence of DNA that is part of an enhancer, a transcription regulatory region that is somewhat distal from the core promoter and which enhances transcription from that promoter.
2 O95718 (/ISS) P11475 (/ISS)
DNA-binding transcription repressor activity, RNA polymerase II-specific GO:0001227
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to repress or decrease transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
2 O08580 (/IDA) O08580 (/IDA)
DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to activate or increase transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
2 O95718 (/ISS) P11475 (/ISS)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
2 O08580 (/IDA) O08580 (/IDA)
RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978
Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in the proximal promoter of a gene transcribed by RNA polymerase II. The proximal promoter is in cis with and relatively close to the core promoter.
1 Q61539 (/IMP)
RNA polymerase II distal enhancer sequence-specific DNA binding GO:0000980
Interacting selectively and non-covalently with a RNA polymerase II (Pol II) distal enhancer. In mammalian cells, enhancers are distal sequences that increase the utilization of some promoters, and can function in either orientation and in any location (upstream or downstream) relative to the core promoter.
1 Q61539 (/IDA)
RNA polymerase II distal enhancer sequence-specific DNA binding GO:0000980
Interacting selectively and non-covalently with a RNA polymerase II (Pol II) distal enhancer. In mammalian cells, enhancers are distal sequences that increase the utilization of some promoters, and can function in either orientation and in any location (upstream or downstream) relative to the core promoter.
1 Q61539 (/IMP)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
1 Q61539 (/IMP)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
1 Q61539 (/ISO)
RNA polymerase II complex binding GO:0000993
Interacting selectively and non-covalently with RNA polymerase II core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of twelve subunits.
1 Q61539 (/IDA)
Enhancer sequence-specific DNA binding GO:0001158
Interacting selectively and non-covalently with a specific sequence of DNA that is part of an enhancer, a transcription regulatory region that is somewhat distal from the core promoter and which enhances transcription from that promoter.
1 Q61539 (/IDA)
Transcription factor binding GO:0008134
Interacting selectively and non-covalently with a transcription factor, a protein required to initiate or regulate transcription.
1 Q61539 (/IPI)
Transcription factor binding GO:0008134
Interacting selectively and non-covalently with a transcription factor, a protein required to initiate or regulate transcription.
1 O95718 (/ISS)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
1 Q61539 (/IMP)

There are 75 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
78 O08580 (/ISS) O08580 (/ISS) P11475 (/ISS) P62509 (/ISS) P62509 (/ISS) P62509 (/ISS) P62509 (/ISS) P62509 (/ISS) P62509 (/ISS) P62509 (/ISS)
(68 more)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
72 O95718 (/ISS) P11475 (/ISS) P62508 (/ISS) P62508 (/ISS) P62508 (/ISS) P62508 (/ISS) P62508 (/ISS) P62508 (/ISS) P62508 (/ISS) P62508 (/ISS)
(62 more)
Positive regulation of cold-induced thermogenesis GO:0120162
Any process that activates or increases the frequency, rate or extent of cold-induced thermogenesis.
70 P62508 (/ISS) P62508 (/ISS) P62508 (/ISS) P62508 (/ISS) P62508 (/ISS) P62508 (/ISS) P62508 (/ISS) P62508 (/ISS) P62508 (/ISS) P62508 (/ISS)
(60 more)
Transcription initiation from RNA polymerase II promoter GO:0006367
Any process involved in the assembly of the RNA polymerase II preinitiation complex (PIC) at an RNA polymerase II promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. Promoter clearance, or release, is the transition between the initiation and elongation phases of transcription.
41 O95718 (/TAS) P11474 (/TAS) P11474 (/TAS) P11474 (/TAS) P11474 (/TAS) P11474 (/TAS) P62508 (/TAS) P62508 (/TAS) P62508 (/TAS) P62508 (/TAS)
(31 more)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
37 O08580 (/IMP) O08580 (/IMP) P62509 (/IMP) P62509 (/IMP) P62509 (/IMP) P62509 (/IMP) P62509 (/IMP) P62509 (/IMP) P62509 (/IMP) P62509 (/IMP)
(27 more)
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
36 O95718 (/IDA) P62508 (/IDA) P62508 (/IDA) P62508 (/IDA) P62508 (/IDA) P62508 (/IDA) P62508 (/IDA) P62508 (/IDA) P62508 (/IDA) P62508 (/IDA)
(26 more)
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
36 P62509 (/ISO) P62509 (/ISO) P62509 (/ISO) P62509 (/ISO) P62509 (/ISO) P62509 (/ISO) P62509 (/ISO) P62509 (/ISO) P62509 (/ISO) P62509 (/ISO)
(26 more)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
36 P62509 (/IDA) P62509 (/IDA) P62509 (/IDA) P62509 (/IDA) P62509 (/IDA) P62509 (/IDA) P62509 (/IDA) P62509 (/IDA) P62509 (/IDA) P62509 (/IDA)
(26 more)
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
35 P62509 (/NAS) P62509 (/NAS) P62509 (/NAS) P62509 (/NAS) P62509 (/NAS) P62509 (/NAS) P62509 (/NAS) P62509 (/NAS) P62509 (/NAS) P62509 (/NAS)
(25 more)
Multicellular organism development GO:0007275
The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
35 P62509 (/NAS) P62509 (/NAS) P62509 (/NAS) P62509 (/NAS) P62509 (/NAS) P62509 (/NAS) P62509 (/NAS) P62509 (/NAS) P62509 (/NAS) P62509 (/NAS)
(25 more)
Positive regulation of cold-induced thermogenesis GO:0120162
Any process that activates or increases the frequency, rate or extent of cold-induced thermogenesis.
35 P62509 (/IMP) P62509 (/IMP) P62509 (/IMP) P62509 (/IMP) P62509 (/IMP) P62509 (/IMP) P62509 (/IMP) P62509 (/IMP) P62509 (/IMP) P62509 (/IMP)
(25 more)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
6 O95718 (/ISS) P11474 (/ISS) P11474 (/ISS) P11474 (/ISS) P11474 (/ISS) P11474 (/ISS)
Transcription, DNA-templated GO:0006351
The cellular synthesis of RNA on a template of DNA.
5 F1QQS8 (/IDA) F6PD98 (/IDA) Q6Q6F3 (/IDA) Q6Q6F4 (/IDA) Q6Q6F6 (/IDA)
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
5 P11474 (/IMP) P11474 (/IMP) P11474 (/IMP) P11474 (/IMP) P11474 (/IMP)
Mitochondrion organization GO:0007005
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components.
5 P11474 (/TAS) P11474 (/TAS) P11474 (/TAS) P11474 (/TAS) P11474 (/TAS)
Otic vesicle development GO:0071599
The process whose specific outcome is the progression of the otic vesicle over time, from its formation to the mature structure. The otic vesicle is a transient embryonic structure formed during development of the vertebrate inner ear.
4 B3DIZ0 (/IMP) F6PD98 (/IMP) Q5RJ38 (/IMP) Q6Q6F4 (/IMP)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
3 Q5QJV7 (/IMP) Q5QJV7 (/IMP) Q61539 (/IMP)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
3 O08580 (/IDA) O08580 (/IDA) Q61539 (/IDA)
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
2 O08580 (/IDA) O08580 (/IDA)
Carbohydrate metabolic process GO:0005975
The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. Includes the formation of carbohydrate derivatives by the addition of a carbohydrate residue to another molecule.
2 Q8WS79 (/IDA) Q9VSE9 (/IDA)
Regulation of transcription by RNA polymerase II GO:0006357
Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.
2 Q8WS79 (/IMP) Q9VSE9 (/IMP)
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
2 Q8WS79 (/IMP) Q9VSE9 (/IMP)
Cell population proliferation GO:0008283
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
2 P11475 (/ISS) Q61539 (/ISS)
Stem cell division GO:0017145
The self-renewing division of a stem cell. A stem cell is an undifferentiated cell, in the embryo or adult, that can undergo unlimited division and give rise to one or several different cell types.
2 O95718 (/ISS) P11475 (/ISS)
Stem cell population maintenance GO:0019827
The process by which an organism or tissue maintains a population of stem cells of a single type. This can be achieved by a number of mechanisms: stem cell asymmetric division maintains stem cell numbers; stem cell symmetric division increases them; maintenance of a stem cell niche maintains the conditions for commitment to the stem cell fate for some types of stem cell; stem cells may arise de novo from other cell types.
2 O95718 (/IDA) Q61539 (/IDA)
Regulation of ossification GO:0030278
Any process that modulates the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance.
2 Q5QJV7 (/IMP) Q5QJV7 (/IMP)
Regulation of ossification GO:0030278
Any process that modulates the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance.
2 O08580 (/ISO) O08580 (/ISO)
Response to estradiol GO:0032355
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen.
2 Q5QJV7 (/IEP) Q5QJV7 (/IEP)
Otolith formation GO:0032475
The process that gives rise to an otolith. This process pertains to the initial formation of a structure from unspecified parts.
2 B3DIZ0 (/IMP) Q5RJ38 (/IMP)
Cell migration involved in gastrulation GO:0042074
The migration of individual cells within the blastocyst to help establish the multi-layered body plan of the organism (gastrulation). For example, the migration of cells from the surface to the interior of the embryo (ingression).
2 F1QQS8 (/IMP) Q6Q6F6 (/IMP)
Regulation of cell population proliferation GO:0042127
Any process that modulates the frequency, rate or extent of cell proliferation.
2 Q5QJV7 (/IMP) Q5QJV7 (/IMP)
Regulation of cell population proliferation GO:0042127
Any process that modulates the frequency, rate or extent of cell proliferation.
2 O08580 (/ISO) O08580 (/ISO)
Cell dedifferentiation GO:0043697
The process in which a specialized cell loses the structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these cells can revert back to the features of the stem cells that were their ancestors.
2 O95718 (/ISS) P11475 (/ISS)
Photoreceptor cell maintenance GO:0045494
Any process preventing the degeneration of the photoreceptor, a specialized cell type that is sensitive to light.
2 O95718 (/ISS) P11475 (/ISS)
Regulation of osteoblast differentiation GO:0045667
Any process that modulates the frequency, rate or extent of osteoblast differentiation.
2 Q5QJV7 (/IMP) Q5QJV7 (/IMP)
Regulation of osteoblast differentiation GO:0045667
Any process that modulates the frequency, rate or extent of osteoblast differentiation.
2 O08580 (/ISO) O08580 (/ISO)
Regulation of osteoclast differentiation GO:0045670
Any process that modulates the frequency, rate or extent of osteoclast differentiation.
2 Q5QJV7 (/IMP) Q5QJV7 (/IMP)
Regulation of osteoclast differentiation GO:0045670
Any process that modulates the frequency, rate or extent of osteoclast differentiation.
2 O08580 (/ISO) O08580 (/ISO)
Positive regulation of glycogen biosynthetic process GO:0045725
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen.
2 P11475 (/IDA) Q61539 (/IDA)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
2 O08580 (/ISO) O08580 (/ISO)
Inner ear development GO:0048839
The process whose specific outcome is the progression of the inner ear over time, from its formation to the mature structure.
2 O95718 (/ISS) P11475 (/ISS)
Cartilage development GO:0051216
The process whose specific outcome is the progression of a cartilage element over time, from its formation to the mature structure. Cartilage elements are skeletal elements that consist of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.
2 Q5QJV7 (/IMP) Q5QJV7 (/IMP)
Cartilage development GO:0051216
The process whose specific outcome is the progression of a cartilage element over time, from its formation to the mature structure. Cartilage elements are skeletal elements that consist of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.
2 O08580 (/ISO) O08580 (/ISO)
Regulation of cartilage development GO:0061035
Any process that modulates the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.
2 F1QQS8 (/IMP) Q6Q6F6 (/IMP)
Positive regulation of transcription involved in G1/S transition of mitotic cell cycle GO:0071931
Any process that activates or increases transcription as part of the G1/S transition of the mitotic cell cycle.
2 O95718 (/ISS) P11475 (/ISS)
Positive regulation of transcription involved in G2/M transition of mitotic cell cycle GO:0090282
Any process that activates or increases the frequency, rate or extent of transcription of target genes that are transcribed as part of the G2/M transition of the mitotic cell cycle.
2 O95718 (/ISS) P11475 (/ISS)
Positive regulation of cellular response to insulin stimulus GO:1900078
Any process that activates or increases the frequency, rate or extent of cellular response to insulin stimulus.
2 Q5QJV7 (/IMP) Q5QJV7 (/IMP)
Positive regulation of cellular response to insulin stimulus GO:1900078
Any process that activates or increases the frequency, rate or extent of cellular response to insulin stimulus.
2 O08580 (/ISO) O08580 (/ISO)
Positive regulation of stem cell population maintenance GO:1902459
Any process that activates or increases the frequency, rate or extent of stem cell population maintenance.
2 O95718 (/ISS) P11475 (/ISS)
Regulation of stem cell division GO:2000035
Any process that modulates the frequency, rate or extent of stem cell division.
2 O95718 (/ISS) P11475 (/ISS)
Negative regulation of stem cell differentiation GO:2000737
Any process that stops, prevents or reduces the frequency, rate or extent of stem cell differentiation.
2 O95718 (/ISS) P11475 (/ISS)
In utero embryonic development GO:0001701
The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus.
1 Q61539 (/IMP)
Trophectodermal cellular morphogenesis GO:0001831
The morphogenesis of trophectoderm cells.
1 Q61539 (/IMP)
Trophectodermal cell proliferation GO:0001834
The proliferation of cells in the trophectoderm.
1 Q61539 (/IMP)
Embryonic placenta development GO:0001892
The embryonically driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin.
1 Q61539 (/IMP)
Cell population proliferation GO:0008283
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
1 Q61539 (/ISO)
Stem cell division GO:0017145
The self-renewing division of a stem cell. A stem cell is an undifferentiated cell, in the embryo or adult, that can undergo unlimited division and give rise to one or several different cell types.
1 Q61539 (/IMP)
Stem cell population maintenance GO:0019827
The process by which an organism or tissue maintains a population of stem cells of a single type. This can be achieved by a number of mechanisms: stem cell asymmetric division maintains stem cell numbers; stem cell symmetric division increases them; maintenance of a stem cell niche maintains the conditions for commitment to the stem cell fate for some types of stem cell; stem cells may arise de novo from other cell types.
1 Q61539 (/IMP)
Stem cell population maintenance GO:0019827
The process by which an organism or tissue maintains a population of stem cells of a single type. This can be achieved by a number of mechanisms: stem cell asymmetric division maintains stem cell numbers; stem cell symmetric division increases them; maintenance of a stem cell niche maintains the conditions for commitment to the stem cell fate for some types of stem cell; stem cells may arise de novo from other cell types.
1 Q61539 (/ISO)
Stem cell population maintenance GO:0019827
The process by which an organism or tissue maintains a population of stem cells of a single type. This can be achieved by a number of mechanisms: stem cell asymmetric division maintains stem cell numbers; stem cell symmetric division increases them; maintenance of a stem cell niche maintains the conditions for commitment to the stem cell fate for some types of stem cell; stem cells may arise de novo from other cell types.
1 P11475 (/ISS)
Cell dedifferentiation GO:0043697
The process in which a specialized cell loses the structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these cells can revert back to the features of the stem cells that were their ancestors.
1 Q61539 (/IDA)
Photoreceptor cell maintenance GO:0045494
Any process preventing the degeneration of the photoreceptor, a specialized cell type that is sensitive to light.
1 Q61539 (/IMP)
Positive regulation of glycogen biosynthetic process GO:0045725
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen.
1 Q61539 (/ISO)
Positive regulation of glycolytic process GO:0045821
Any process that activates or increases the frequency, rate or extent of glycolysis.
1 P11475 (/IDA)
Positive regulation of glycolytic process GO:0045821
Any process that activates or increases the frequency, rate or extent of glycolysis.
1 Q61539 (/ISO)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
1 Q61539 (/IDA)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
1 P11475 (/ISS)
Inner ear development GO:0048839
The process whose specific outcome is the progression of the inner ear over time, from its formation to the mature structure.
1 Q61539 (/IMP)
Positive regulation of transcription involved in G1/S transition of mitotic cell cycle GO:0071931
Any process that activates or increases transcription as part of the G1/S transition of the mitotic cell cycle.
1 Q61539 (/IMP)
Positive regulation of transcription involved in G2/M transition of mitotic cell cycle GO:0090282
Any process that activates or increases the frequency, rate or extent of transcription of target genes that are transcribed as part of the G2/M transition of the mitotic cell cycle.
1 Q61539 (/IMP)
Positive regulation of stem cell population maintenance GO:1902459
Any process that activates or increases the frequency, rate or extent of stem cell population maintenance.
1 Q61539 (/IDA)
Positive regulation of stem cell population maintenance GO:1902459
Any process that activates or increases the frequency, rate or extent of stem cell population maintenance.
1 Q61539 (/IMP)
Regulation of stem cell division GO:2000035
Any process that modulates the frequency, rate or extent of stem cell division.
1 Q61539 (/IDA)
Regulation of stem cell division GO:2000035
Any process that modulates the frequency, rate or extent of stem cell division.
1 Q61539 (/IMP)
Negative regulation of stem cell differentiation GO:2000737
Any process that stops, prevents or reduces the frequency, rate or extent of stem cell differentiation.
1 Q61539 (/IMP)

There are 14 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
41 O95718 (/TAS) P11474 (/TAS) P11474 (/TAS) P11474 (/TAS) P11474 (/TAS) P11474 (/TAS) P62508 (/TAS) P62508 (/TAS) P62508 (/TAS) P62508 (/TAS)
(31 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
35 P62509 (/NAS) P62509 (/NAS) P62509 (/NAS) P62509 (/NAS) P62509 (/NAS) P62509 (/NAS) P62509 (/NAS) P62509 (/NAS) P62509 (/NAS) P62509 (/NAS)
(25 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
15 O08580 (/IDA) O08580 (/IDA) P11474 (/IDA) P11474 (/IDA) P11474 (/IDA) P11474 (/IDA) P11474 (/IDA) Q569H8 (/IDA) Q569H8 (/IDA) Q569H8 (/IDA)
(5 more)
Fibrillar center GO:0001650
A structure found most metazoan nucleoli, but not usually found in lower eukaryotes; surrounded by the dense fibrillar component; the zone of transcription from multiple copies of the pre-rRNA genes is in the border region between these two structures.
10 P11474 (/IDA) P11474 (/IDA) P11474 (/IDA) P11474 (/IDA) P11474 (/IDA) Q569H8 (/IDA) Q569H8 (/IDA) Q569H8 (/IDA) Q569H8 (/IDA) Q569H8 (/IDA)
Microtubule cytoskeleton GO:0015630
The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins.
10 P11474 (/IDA) P11474 (/IDA) P11474 (/IDA) P11474 (/IDA) P11474 (/IDA) Q569H8 (/IDA) Q569H8 (/IDA) Q569H8 (/IDA) Q569H8 (/IDA) Q569H8 (/IDA)
Intercellular bridge GO:0045171
A direct connection between the cytoplasm of two cells that is formed following the completion of cleavage furrow ingression during cell division. They are usually present only briefly prior to completion of cytokinesis. However, in some cases, such as the bridges between germ cells during their development, they become stabilised.
10 P11474 (/IDA) P11474 (/IDA) P11474 (/IDA) P11474 (/IDA) P11474 (/IDA) Q569H8 (/IDA) Q569H8 (/IDA) Q569H8 (/IDA) Q569H8 (/IDA) Q569H8 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
7 O08580 (/ISS) O08580 (/ISS) O95718 (/ISS) P11475 (/ISS) Q5QJV7 (/ISS) Q5QJV7 (/ISS) Q6QMY5 (/ISS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
6 P11474 (/IDA) P11474 (/IDA) P11474 (/IDA) P11474 (/IDA) P11474 (/IDA) Q61539 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
5 F1QQS8 (/IC) F6PD98 (/IC) Q6Q6F3 (/IC) Q6Q6F4 (/IC) Q6Q6F6 (/IC)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
5 O95718 (/ISS) P11475 (/ISS) Q6QMY5 (/ISS) Q8WS79 (/ISS) Q9VSE9 (/ISS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
5 P11474 (/TAS) P11474 (/TAS) P11474 (/TAS) P11474 (/TAS) P11474 (/TAS)
Condensed chromosome GO:0000793
A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct structure.
2 O95718 (/ISS) P11475 (/ISS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 O08580 (/ISO) O08580 (/ISO)
Condensed chromosome GO:0000793
A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct structure.
1 Q61539 (/IMP)
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