The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Antithrombin, subunit I, domain 2
".
FunFam 17: Uncharacterized protein, isoform B
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 2 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Serine-type endopeptidase inhibitor activity GO:0004867
Stops, prevents or reduces the activity of serine-type endopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide bonds in a polypeptide chain; a serine residue (and a histidine residue) are at the active center of the enzyme.
|
10 | Q7K8Y3 (/IDA) Q7K8Y5 (/IDA) Q8MM39 (/IDA) Q8MM49 (/IDA) Q8MPN5 (/IDA) Q8MPN6 (/IDA) Q8MPN7 (/IDA) Q8MPN8 (/IDA) Q8T0M5 (/IDA) Q9U1I5 (/IDA) |
|
Cysteine-type endopeptidase inhibitor activity GO:0004869
Stops, prevents or reduces the activity of a cysteine-type endopeptidase, any enzyme that hydrolyzes peptide bonds in polypeptides by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.
|
10 | Q7K8Y3 (/IDA) Q7K8Y5 (/IDA) Q8MM39 (/IDA) Q8MM49 (/IDA) Q8MPN5 (/IDA) Q8MPN6 (/IDA) Q8MPN7 (/IDA) Q8MPN8 (/IDA) Q8T0M5 (/IDA) Q9U1I5 (/IDA) |
There are 3 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Negative regulation of endopeptidase activity GO:0010951
Any process that decreases the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins.
|
10 | Q7K8Y3 (/IDA) Q7K8Y5 (/IDA) Q8MM39 (/IDA) Q8MM49 (/IDA) Q8MPN5 (/IDA) Q8MPN6 (/IDA) Q8MPN7 (/IDA) Q8MPN8 (/IDA) Q8T0M5 (/IDA) Q9U1I5 (/IDA) |
|
Negative regulation of protein processing GO:0010955
Any process that decreases the rate, frequency or extent of protein maturation by peptide bond cleavage.
|
10 | Q7K8Y3 (/IMP) Q7K8Y5 (/IMP) Q8MM39 (/IMP) Q8MM49 (/IMP) Q8MPN5 (/IMP) Q8MPN6 (/IMP) Q8MPN7 (/IMP) Q8MPN8 (/IMP) Q8T0M5 (/IMP) Q9U1I5 (/IMP) |
|
Negative regulation of peptide hormone processing GO:0060570
Any process that decreases the rate, frequency or extent of peptide hormone processing. Peptide hormone processing is the generation of a mature peptide hormone by posttranslational processing of a prohormone.
|
10 | Q7K8Y3 (/IMP) Q7K8Y5 (/IMP) Q8MM39 (/IMP) Q8MM49 (/IMP) Q8MPN5 (/IMP) Q8MPN6 (/IMP) Q8MPN7 (/IMP) Q8MPN8 (/IMP) Q8T0M5 (/IMP) Q9U1I5 (/IMP) |
There are 1 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
10 | Q7K8Y3 (/IDA) Q7K8Y5 (/IDA) Q8MM39 (/IDA) Q8MM49 (/IDA) Q8MPN5 (/IDA) Q8MPN6 (/IDA) Q8MPN7 (/IDA) Q8MPN8 (/IDA) Q8T0M5 (/IDA) Q9U1I5 (/IDA) |
