The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Band 7 domain
".
FunFam 8: Stomatin-like protein 2, mitochondrial
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 8 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Signaling receptor binding GO:0005102
Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
|
3 | Q9UJZ1 (/TAS) Q9UJZ1 (/TAS) Q9UJZ1 (/TAS) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
3 | Q9UJZ1 (/IPI) Q9UJZ1 (/IPI) Q9UJZ1 (/IPI) |
GTPase binding GO:0051020
Interacting selectively and non-covalently with a GTPase, any enzyme that catalyzes the hydrolysis of GTP.
|
3 | Q9UJZ1 (/IPI) Q9UJZ1 (/IPI) Q9UJZ1 (/IPI) |
Cardiolipin binding GO:1901612
Interacting selectively and non-covalently with cardiolipin.
|
3 | Q9UJZ1 (/IDA) Q9UJZ1 (/IDA) Q9UJZ1 (/IDA) |
Cardiolipin binding GO:1901612
Interacting selectively and non-covalently with cardiolipin.
|
3 | Q32LL2 (/ISS) Q4FZT0 (/ISS) Q99JB2 (/ISS) |
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
|
2 | Q93VP9 (/IDA) Q93VP9 (/IDA) |
GTPase binding GO:0051020
Interacting selectively and non-covalently with a GTPase, any enzyme that catalyzes the hydrolysis of GTP.
|
1 | Q99JB2 (/ISO) |
Cardiolipin binding GO:1901612
Interacting selectively and non-covalently with cardiolipin.
|
1 | Q99JB2 (/ISO) |
There are 40 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Lipid localization GO:0010876
Any process in which a lipid is transported to, or maintained in, a specific location.
|
5 | Q32LL2 (/ISS) Q4FZT0 (/ISS) Q9UJZ1 (/ISS) Q9UJZ1 (/ISS) Q9UJZ1 (/ISS) |
Interleukin-2 production GO:0032623
The appearance of interleukin-2 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
|
5 | Q32LL2 (/ISS) Q4FZT0 (/ISS) Q9UJZ1 (/ISS) Q9UJZ1 (/ISS) Q9UJZ1 (/ISS) |
Mitochondrial protein processing GO:0034982
The peptide cleavage of mitochondrial proteins, including cleavage contributing to their import.
|
5 | Q32LL2 (/ISS) Q4FZT0 (/ISS) Q9UJZ1 (/ISS) Q9UJZ1 (/ISS) Q9UJZ1 (/ISS) |
CD4-positive, alpha-beta T cell activation GO:0035710
The change in morphology and behavior of a CD4-positive, alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
|
5 | Q32LL2 (/ISS) Q4FZT0 (/ISS) Q9UJZ1 (/ISS) Q9UJZ1 (/ISS) Q9UJZ1 (/ISS) |
Stress-induced mitochondrial fusion GO:1990046
Merging of two or more mitochondria within a cell to form a single compartment, as a result of a disturbance in cellular homeostasis.
|
5 | Q32LL2 (/ISS) Q4FZT0 (/ISS) Q9UJZ1 (/ISS) Q9UJZ1 (/ISS) Q9UJZ1 (/ISS) |
Mitochondrial ATP synthesis coupled proton transport GO:0042776
The transport of protons across a mitochondrial membrane to generate an electrochemical gradient (proton-motive force) that powers ATP synthesis.
|
4 | Q99JB2 (/IMP) Q9UJZ1 (/IMP) Q9UJZ1 (/IMP) Q9UJZ1 (/IMP) |
Mitochondrial calcium ion transmembrane transport GO:0006851
The process in which a calcium ion (Ca2+) is transported across a mitochondrial membrane, into or out of the mitochondrion.
|
3 | Q9UJZ1 (/IMP) Q9UJZ1 (/IMP) Q9UJZ1 (/IMP) |
Mitochondrial calcium ion transmembrane transport GO:0006851
The process in which a calcium ion (Ca2+) is transported across a mitochondrial membrane, into or out of the mitochondrion.
|
3 | Q32LL2 (/ISS) Q4FZT0 (/ISS) Q99JB2 (/ISS) |
Mitochondrial calcium ion transmembrane transport GO:0006851
The process in which a calcium ion (Ca2+) is transported across a mitochondrial membrane, into or out of the mitochondrion.
|
3 | Q9UJZ1 (/TAS) Q9UJZ1 (/TAS) Q9UJZ1 (/TAS) |
Cellular calcium ion homeostasis GO:0006874
Any process involved in the maintenance of an internal steady state of calcium ions at the level of a cell.
|
3 | Q9UJZ1 (/IMP) Q9UJZ1 (/IMP) Q9UJZ1 (/IMP) |
Cellular calcium ion homeostasis GO:0006874
Any process involved in the maintenance of an internal steady state of calcium ions at the level of a cell.
|
3 | Q32LL2 (/ISS) Q4FZT0 (/ISS) Q99JB2 (/ISS) |
Mitochondrion organization GO:0007005
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components.
|
3 | Q9UJZ1 (/IMP) Q9UJZ1 (/IMP) Q9UJZ1 (/IMP) |
Mitochondrion organization GO:0007005
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components.
|
3 | Q32LL2 (/ISS) Q4FZT0 (/ISS) Q99JB2 (/ISS) |
Positive regulation of mitochondrial membrane potential GO:0010918
Any process that activates or increases the frequency, rate or extent of establishment or extent of a mitochondrial membrane potential, the electric potential existing across any mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.
|
3 | Q9UJZ1 (/IMP) Q9UJZ1 (/IMP) Q9UJZ1 (/IMP) |
Positive regulation of mitochondrial membrane potential GO:0010918
Any process that activates or increases the frequency, rate or extent of establishment or extent of a mitochondrial membrane potential, the electric potential existing across any mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.
|
3 | Q32LL2 (/ISS) Q4FZT0 (/ISS) Q99JB2 (/ISS) |
T cell receptor signaling pathway GO:0050852
A series of molecular signals initiated by the cross-linking of an antigen receptor on a T cell.
|
3 | Q9UJZ1 (/IMP) Q9UJZ1 (/IMP) Q9UJZ1 (/IMP) |
T cell receptor signaling pathway GO:0050852
A series of molecular signals initiated by the cross-linking of an antigen receptor on a T cell.
|
3 | Q32LL2 (/ISS) Q4FZT0 (/ISS) Q99JB2 (/ISS) |
Protein complex oligomerization GO:0051259
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers; protein oligomers may be composed of different or identical monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
|
3 | Q9UJZ1 (/IDA) Q9UJZ1 (/IDA) Q9UJZ1 (/IDA) |
Protein complex oligomerization GO:0051259
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers; protein oligomers may be composed of different or identical monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
|
3 | Q32LL2 (/ISS) Q4FZT0 (/ISS) Q99JB2 (/ISS) |
Positive regulation of mitochondrial DNA replication GO:0090297
Any process that increases the rate, frequency or extent of the process in which new strands of DNA are synthesized in the mitochondrion.
|
3 | Q9UJZ1 (/IMP) Q9UJZ1 (/IMP) Q9UJZ1 (/IMP) |
Positive regulation of mitochondrial DNA replication GO:0090297
Any process that increases the rate, frequency or extent of the process in which new strands of DNA are synthesized in the mitochondrion.
|
3 | Q32LL2 (/ISS) Q4FZT0 (/ISS) Q99JB2 (/ISS) |
Positive regulation of cardiolipin metabolic process GO:1900210
Any process that activates or increases the frequency, rate or extent of cardiolipin metabolic process.
|
3 | Q9UJZ1 (/IMP) Q9UJZ1 (/IMP) Q9UJZ1 (/IMP) |
Positive regulation of cardiolipin metabolic process GO:1900210
Any process that activates or increases the frequency, rate or extent of cardiolipin metabolic process.
|
3 | Q32LL2 (/ISS) Q4FZT0 (/ISS) Q99JB2 (/ISS) |
Mitochondrial ATP synthesis coupled proton transport GO:0042776
The transport of protons across a mitochondrial membrane to generate an electrochemical gradient (proton-motive force) that powers ATP synthesis.
|
2 | Q32LL2 (/ISS) Q4FZT0 (/ISS) |
Mitochondrial respirasome assembly GO:0097250
The aggregation, arrangement and bonding together of a set of respiratory enzyme complexes of the mitochondrial inner membrane (including, for example, complex II, complex III, complex IV) to form a large supercomplex.
|
2 | Q93VP9 (/IMP) Q93VP9 (/IMP) |
Mitochondrial calcium ion transmembrane transport GO:0006851
The process in which a calcium ion (Ca2+) is transported across a mitochondrial membrane, into or out of the mitochondrion.
|
1 | Q99JB2 (/ISO) |
Cellular calcium ion homeostasis GO:0006874
Any process involved in the maintenance of an internal steady state of calcium ions at the level of a cell.
|
1 | Q99JB2 (/ISO) |
Mitochondrion organization GO:0007005
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components.
|
1 | Q99JB2 (/ISO) |
Mitochondrial membrane organization GO:0007006
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrial membrane, either of the lipid bilayer surrounding a mitochondrion.
|
1 | O60121 (/ISS) |
Lipid localization GO:0010876
Any process in which a lipid is transported to, or maintained in, a specific location.
|
1 | Q99JB2 (/IMP) |
Positive regulation of mitochondrial membrane potential GO:0010918
Any process that activates or increases the frequency, rate or extent of establishment or extent of a mitochondrial membrane potential, the electric potential existing across any mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.
|
1 | Q99JB2 (/ISO) |
Interleukin-2 production GO:0032623
The appearance of interleukin-2 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
|
1 | Q99JB2 (/IMP) |
Mitochondrial protein processing GO:0034982
The peptide cleavage of mitochondrial proteins, including cleavage contributing to their import.
|
1 | Q99JB2 (/IMP) |
CD4-positive, alpha-beta T cell activation GO:0035710
The change in morphology and behavior of a CD4-positive, alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
|
1 | Q99JB2 (/IMP) |
Mitochondrial ATP synthesis coupled proton transport GO:0042776
The transport of protons across a mitochondrial membrane to generate an electrochemical gradient (proton-motive force) that powers ATP synthesis.
|
1 | Q99JB2 (/ISO) |
T cell receptor signaling pathway GO:0050852
A series of molecular signals initiated by the cross-linking of an antigen receptor on a T cell.
|
1 | Q99JB2 (/ISO) |
Protein complex oligomerization GO:0051259
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers; protein oligomers may be composed of different or identical monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
|
1 | Q99JB2 (/ISO) |
Positive regulation of mitochondrial DNA replication GO:0090297
Any process that increases the rate, frequency or extent of the process in which new strands of DNA are synthesized in the mitochondrion.
|
1 | Q99JB2 (/ISO) |
Positive regulation of cardiolipin metabolic process GO:1900210
Any process that activates or increases the frequency, rate or extent of cardiolipin metabolic process.
|
1 | Q99JB2 (/ISO) |
Stress-induced mitochondrial fusion GO:1990046
Merging of two or more mitochondria within a cell to form a single compartment, as a result of a disturbance in cellular homeostasis.
|
1 | Q99JB2 (/IMP) |
There are 19 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
5 | H2FLJ1 (/IDA) Q93VP9 (/IDA) Q93VP9 (/IDA) Q99JB2 (/IDA) Q9LVW0 (/IDA) |
Extrinsic component of plasma membrane GO:0019897
The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
|
4 | Q99JB2 (/IDA) Q9UJZ1 (/IDA) Q9UJZ1 (/IDA) Q9UJZ1 (/IDA) |
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
|
3 | Q9UJZ1 (/IDA) Q9UJZ1 (/IDA) Q9UJZ1 (/IDA) |
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
|
3 | Q9UJZ1 (/TAS) Q9UJZ1 (/TAS) Q9UJZ1 (/TAS) |
Mitochondrial intermembrane space GO:0005758
The region between the inner and outer lipid bilayers of the mitochondrial envelope.
|
3 | Q9UJZ1 (/IDA) Q9UJZ1 (/IDA) Q9UJZ1 (/IDA) |
Mitochondrial intermembrane space GO:0005758
The region between the inner and outer lipid bilayers of the mitochondrial envelope.
|
3 | Q32LL2 (/ISS) Q4FZT0 (/ISS) Q99JB2 (/ISS) |
Cytoskeleton GO:0005856
Any of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.
|
3 | Q9UJZ1 (/TAS) Q9UJZ1 (/TAS) Q9UJZ1 (/TAS) |
Membrane raft GO:0045121
Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions.
|
3 | Q9UJZ1 (/IDA) Q9UJZ1 (/IDA) Q9UJZ1 (/IDA) |
Membrane raft GO:0045121
Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions.
|
3 | Q32LL2 (/ISS) Q4FZT0 (/ISS) Q99JB2 (/ISS) |
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
2 | O60121 (/HDA) Q99JB2 (/HDA) |
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
|
2 | O60121 (/ISO) Q99JB2 (/ISO) |
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
|
2 | Q32LL2 (/ISS) Q4FZT0 (/ISS) |
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
2 | Q93VP9 (/IDA) Q93VP9 (/IDA) |
Extrinsic component of plasma membrane GO:0019897
The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
|
2 | Q32LL2 (/ISS) Q4FZT0 (/ISS) |
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
|
1 | Q99JB2 (/HDA) |
Mitochondrial intermembrane space GO:0005758
The region between the inner and outer lipid bilayers of the mitochondrial envelope.
|
1 | Q99JB2 (/ISO) |
Extrinsic component of plasma membrane GO:0019897
The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
|
1 | Q99JB2 (/ISO) |
Membrane raft GO:0045121
Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions.
|
1 | H2FLJ1 (/HDA) |
Membrane raft GO:0045121
Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions.
|
1 | Q99JB2 (/ISO) |