The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
DNA ligase/mRNA capping enzyme
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 11: mRNA-capping enzyme subunit alpha

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
8 P40997 (/IPI) Q01159 (/IPI) Q01159 (/IPI) Q01159 (/IPI) Q01159 (/IPI) Q01159 (/IPI) Q01159 (/IPI) Q01159 (/IPI)
MRNA guanylyltransferase activity GO:0004484
Catalysis of the reaction: GTP + (5')pp-Pur-mRNA = diphosphate + G(5')ppp-Pur-mRNA; G(5')ppp-Pur-mRNA is mRNA containing a guanosine residue linked 5' through three phosphates to the 5' position of the terminal residue.
7 Q01159 (/IMP) Q01159 (/IMP) Q01159 (/IMP) Q01159 (/IMP) Q01159 (/IMP) Q01159 (/IMP) Q01159 (/IMP)
MRNA guanylyltransferase activity GO:0004484
Catalysis of the reaction: GTP + (5')pp-Pur-mRNA = diphosphate + G(5')ppp-Pur-mRNA; G(5')ppp-Pur-mRNA is mRNA containing a guanosine residue linked 5' through three phosphates to the 5' position of the terminal residue.
1 P40997 (/IDA)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
7-methylguanosine mRNA capping GO:0006370
Addition of the 7-methylguanosine cap to the 5' end of a nascent messenger RNA transcript.
7 Q01159 (/IMP) Q01159 (/IMP) Q01159 (/IMP) Q01159 (/IMP) Q01159 (/IMP) Q01159 (/IMP) Q01159 (/IMP)
TRNA processing GO:0008033
The process in which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group.
7 Q01159 (/IMP) Q01159 (/IMP) Q01159 (/IMP) Q01159 (/IMP) Q01159 (/IMP) Q01159 (/IMP) Q01159 (/IMP)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
7 Q01159 (/IGI) Q01159 (/IGI) Q01159 (/IGI) Q01159 (/IGI) Q01159 (/IGI) Q01159 (/IGI) Q01159 (/IGI)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
7 Q01159 (/IMP) Q01159 (/IMP) Q01159 (/IMP) Q01159 (/IMP) Q01159 (/IMP) Q01159 (/IMP) Q01159 (/IMP)
7-methylguanosine mRNA capping GO:0006370
Addition of the 7-methylguanosine cap to the 5' end of a nascent messenger RNA transcript.
1 P40997 (/ISO)
7-methylguanosine RNA capping GO:0009452
The sequence of enzymatic reactions by which the 5' cap structure, an inverted 7-methylguanosine linked via a 5'-5' triphosphate bridge (m7G(5')ppp(5')X) to the first transcribed residue, is added to a nascent transcript.
1 P40997 (/IDA)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
7 Q01159 (/IPI) Q01159 (/IPI) Q01159 (/IPI) Q01159 (/IPI) Q01159 (/IPI) Q01159 (/IPI) Q01159 (/IPI)
MRNA cap methyltransferase complex GO:0031533
A protein complex that consists of an RNA 5' triphosphatase and a guanyl transferase (Cet1p and Ceg1p in S. cerevisiae; Pct1 and Ceg1 in S. pombe) and is involved in mRNA capping.
7 Q01159 (/IGI) Q01159 (/IGI) Q01159 (/IGI) Q01159 (/IGI) Q01159 (/IGI) Q01159 (/IGI) Q01159 (/IGI)
MRNA cap methyltransferase complex GO:0031533
A protein complex that consists of an RNA 5' triphosphatase and a guanyl transferase (Cet1p and Ceg1p in S. cerevisiae; Pct1 and Ceg1 in S. pombe) and is involved in mRNA capping.
7 Q01159 (/IPI) Q01159 (/IPI) Q01159 (/IPI) Q01159 (/IPI) Q01159 (/IPI) Q01159 (/IPI) Q01159 (/IPI)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 P40997 (/HDA)
MRNA cap methyltransferase complex GO:0031533
A protein complex that consists of an RNA 5' triphosphatase and a guanyl transferase (Cet1p and Ceg1p in S. cerevisiae; Pct1 and Ceg1 in S. pombe) and is involved in mRNA capping.
1 P40997 (/ISS)
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