The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
ATP-grasp fold, B domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 139: [Butirosin acyl-carrier protein]--L-glutamate liga...

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
[Butirosin acyl-carrier protein]--L-glutamate ligase. [EC: 6.2.1.39]
(1) ATP + L-glutamate + [BtrI acyl-carrier protein] = ADP + phosphate + L-glutamyl-[BtrI acyl-carrier protein]. (2) ATP + L-glutamate + 4-amino butanoyl-[BtrI acyl-carrier protein] = ADP + phosphate + 4-(L-gamma-glutamylamino)butanoyl-[BtrI acyl-carrier protein].
  • Catalyzes two steps in the biosynthesis of the side chain of the aminoglycoside antibiotics of the butirosin family.
  • The enzyme adds one molecule of L-glutamate to a dedicated acyl- carrier protein, and following decarboxylation of the product by EC 4.1.1.95, adds a second L-glutamate molecule.
1 Q4H4E7
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