The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 37: Probable tRNA N6-adenosine threonylcarbamoyltransf...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
6 P36132 (/IPI) P36132 (/IPI) P36132 (/IPI) Q9NPF4 (/IPI) Q9NPF4 (/IPI) Q9NPF4 (/IPI)
Chromatin DNA binding GO:0031490
Interacting selectively and non-covalently with DNA that is assembled into chromatin.
3 P36132 (/IDA) P36132 (/IDA) P36132 (/IDA)
TRNA binding GO:0000049
Interacting selectively and non-covalently with transfer RNA.
1 Q9UXT7 (/IDA)
Single-stranded RNA binding GO:0003727
Interacting selectively and non-covalently with single-stranded RNA.
1 Q9UXT7 (/IDA)
N(6)-L-threonylcarbamoyladenine synthase activity GO:0061711
Catalysis of the reaction: L-threonylcarbamoyladenylate + adenine(37) in tRNA = AMP + N(6)-L-threonylcarbamoyladenine(37) in tRNA.
1 O94637 (/ISM)

There are 13 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
TRNA threonylcarbamoyladenosine modification GO:0002949
The attachment of a carbonyl group and a threonine to the amino group of the adenine residue immediately 3' of the anticodon, in tRNAs that decode ANN codons (where N is any base).
7 Q0VCI1 (/ISS) Q0VCI1 (/ISS) Q5RHZ6 (/ISS) Q7SYR1 (/ISS) Q8BWU5 (/ISS) Q8BWU5 (/ISS) Q9WVS2 (/ISS)
TRNA threonylcarbamoyladenosine modification GO:0002949
The attachment of a carbonyl group and a threonine to the amino group of the adenine residue immediately 3' of the anticodon, in tRNAs that decode ANN codons (where N is any base).
4 Q9NPF4 (/IDA) Q9NPF4 (/IDA) Q9NPF4 (/IDA) Q9UXT7 (/IDA)
Telomere maintenance via recombination GO:0000722
Any recombinational process that contributes to the maintenance of proper telomeric length.
3 P36132 (/IGI) P36132 (/IGI) P36132 (/IGI)
Telomere maintenance via recombination GO:0000722
Any recombinational process that contributes to the maintenance of proper telomeric length.
3 P36132 (/IMP) P36132 (/IMP) P36132 (/IMP)
Telomere maintenance GO:0000723
Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins, the length of telomeric DNA and the replication and repair of the DNA. These processes includes those that shorten, lengthen, replicate and repair the telomeric DNA sequences.
3 P36132 (/IPI) P36132 (/IPI) P36132 (/IPI)
TRNA threonylcarbamoyladenosine modification GO:0002949
The attachment of a carbonyl group and a threonine to the amino group of the adenine residue immediately 3' of the anticodon, in tRNAs that decode ANN codons (where N is any base).
3 O94637 (/ISO) Q8BWU5 (/ISO) Q8BWU5 (/ISO)
TRNA modification GO:0006400
The covalent alteration of one or more nucleotides within a tRNA molecule to produce a tRNA molecule with a sequence that differs from that coded genetically.
3 P36132 (/IDA) P36132 (/IDA) P36132 (/IDA)
TRNA modification GO:0006400
The covalent alteration of one or more nucleotides within a tRNA molecule to produce a tRNA molecule with a sequence that differs from that coded genetically.
3 P36132 (/TAS) P36132 (/TAS) P36132 (/TAS)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
3 P36132 (/IPI) P36132 (/IPI) P36132 (/IPI)
Chromosome organization GO:0051276
A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. This term covers covalent modifications at the molecular level as well as spatial relationships among the major components of a chromosome.
3 P36132 (/IMP) P36132 (/IMP) P36132 (/IMP)
TRNA threonylcarbamoyladenosine metabolic process GO:0070525
The chemical reactions and pathways involving tRNA threonylcarbamoyladenosine, a modified nucleoside found in some tRNA molecules.
3 P36132 (/IMP) P36132 (/IMP) P36132 (/IMP)
TRNA threonylcarbamoyladenosine modification GO:0002949
The attachment of a carbonyl group and a threonine to the amino group of the adenine residue immediately 3' of the anticodon, in tRNAs that decode ANN codons (where N is any base).
1 Q9VV41 (/IMP)
Positive regulation of translational initiation GO:0045948
Any process that activates or increases the frequency, rate or extent of translational initiation.
1 Q9VV41 (/IMP)

There are 20 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
EKC/KEOPS complex GO:0000408
A protein complex involved in t6A tRNA modification; originally proposed to be involved in transcription as well as promoting telomere uncapping and telomere elongation. For example, in Saccharomyces cerevisiae the complex contains Bud32p, Kae1p, Gon7p, Cgi121p, and Pcc1p.
7 P36132 (/IDA) P36132 (/IDA) P36132 (/IDA) Q9NPF4 (/IDA) Q9NPF4 (/IDA) Q9NPF4 (/IDA) Q9UXT7 (/IDA)
EKC/KEOPS complex GO:0000408
A protein complex involved in t6A tRNA modification; originally proposed to be involved in transcription as well as promoting telomere uncapping and telomere elongation. For example, in Saccharomyces cerevisiae the complex contains Bud32p, Kae1p, Gon7p, Cgi121p, and Pcc1p.
7 Q0VCI1 (/ISS) Q0VCI1 (/ISS) Q5RHZ6 (/ISS) Q7SYR1 (/ISS) Q8BWU5 (/ISS) Q8BWU5 (/ISS) Q9WVS2 (/ISS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
7 Q0VCI1 (/ISS) Q0VCI1 (/ISS) Q5RHZ6 (/ISS) Q7SYR1 (/ISS) Q8BWU5 (/ISS) Q8BWU5 (/ISS) Q9WVS2 (/ISS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
7 Q0VCI1 (/ISS) Q0VCI1 (/ISS) Q5RHZ6 (/ISS) Q7SYR1 (/ISS) Q8BWU5 (/ISS) Q8BWU5 (/ISS) Q9WVS2 (/ISS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
4 O94637 (/HDA) P36132 (/HDA) P36132 (/HDA) P36132 (/HDA)
EKC/KEOPS complex GO:0000408
A protein complex involved in t6A tRNA modification; originally proposed to be involved in transcription as well as promoting telomere uncapping and telomere elongation. For example, in Saccharomyces cerevisiae the complex contains Bud32p, Kae1p, Gon7p, Cgi121p, and Pcc1p.
3 O94637 (/ISO) Q8BWU5 (/ISO) Q8BWU5 (/ISO)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
3 Q9NPF4 (/IDA) Q9NPF4 (/IDA) Q9NPF4 (/IDA)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
3 Q9NPF4 (/IDA) Q9NPF4 (/IDA) Q9NPF4 (/IDA)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
3 P36132 (/TAS) P36132 (/TAS) P36132 (/TAS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 P36132 (/HDA) P36132 (/HDA) P36132 (/HDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 Q9NPF4 (/IDA) Q9NPF4 (/IDA) Q9NPF4 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
3 Q9NPF4 (/IDA) Q9NPF4 (/IDA) Q9NPF4 (/IDA)
Nuclear speck GO:0016607
A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.
3 Q9NPF4 (/IDA) Q9NPF4 (/IDA) Q9NPF4 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 Q8BWU5 (/ISO) Q8BWU5 (/ISO)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
2 Q8BWU5 (/ISO) Q8BWU5 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 Q8BWU5 (/ISO) Q8BWU5 (/ISO)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 Q8BWU5 (/ISO) Q8BWU5 (/ISO)
Nuclear speck GO:0016607
A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.
2 Q8BWU5 (/ISO) Q8BWU5 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 O94637 (/HDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 O49653 (/IDA)
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