The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Exopolyphosphatase. Domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 8: Apyrase 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Guanosine-diphosphatase activity GO:0004382
Catalysis of the reaction: GDP + H2O = GMP + phosphate.
2 Q9SQG2 (/IDA) Q9XU84 (/IDA)
Uridine-diphosphatase activity GO:0045134
Catalysis of the reaction: UDP + H2O = UMP + phosphate.
2 Q9SQG2 (/IDA) Q9XU84 (/IDA)
Nucleoside-diphosphatase activity GO:0017110
Catalysis of the reaction: a nucleoside diphosphate + H2O = a nucleotide + phosphate.
1 Q9FVC2 (/IDA)
CTPase activity GO:0043273
Catalysis of the reaction: CTP + H2O = CDP + phosphate. May or may not be coupled to another reaction.
1 Q9FVC2 (/IDA)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Pollen germination GO:0009846
The physiological and developmental changes that occur in a heterosporous plant pollen grain, beginning with hydration and terminating with the emergence of the pollen tube through the aperture.
1 Q9SQG2 (/IGI)
Nodulation GO:0009877
The formation of nitrogen-fixing root nodules on plant roots.
1 Q9FVC2 (/IMP)
UDP metabolic process GO:0046048
The chemical reactions and pathways involving UDP, uridine (5'-)diphosphate.
1 Q9XU84 (/IDA)
GDP metabolic process GO:0046710
The chemical reactions and pathways involving GDP, guanosine 5'-diphosphate.
1 Q9XU84 (/IDA)

There are 7 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Golgi membrane GO:0000139
The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
1 Q9FVC3 (/IDA)
Endosome GO:0005768
A vacuole to which materials ingested by endocytosis are delivered.
1 Q9SQG2 (/IDA)
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
1 Q9SQG2 (/IDA)
Trans-Golgi network GO:0005802
The network of interconnected tubular and cisternal structures located within the Golgi apparatus on the side distal to the endoplasmic reticulum, from which secretory vesicles emerge. The trans-Golgi network is important in the later stages of protein secretion where it is thought to play a key role in the sorting and targeting of secreted proteins to the correct destination.
1 Q9SQG2 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q9FVC2 (/IDA)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 Q9SQG2 (/IDA)
Cytoplasmic vesicle membrane GO:0030659
The lipid bilayer surrounding a cytoplasmic vesicle.
1 Q9XU84 (/IDA)
CATH-Gene3D is a Global Biodata Core Resource Learn more...