The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Exopolyphosphatase. Domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 4: Ectonucleoside triphosphate diphosphohydrolase 5

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 11 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Guanosine-diphosphatase activity GO:0004382
Catalysis of the reaction: GDP + H2O = GMP + phosphate.
7 D2GZV9 (/ISS) E1BPW0 (/ISS) E1C1L6 (/ISS) O75356 (/ISS) O75356 (/ISS) Q6P6S9 (/ISS) Q9QYC8 (/ISS)
Uridine-diphosphatase activity GO:0045134
Catalysis of the reaction: UDP + H2O = UMP + phosphate.
7 D2GZV9 (/ISS) E1BPW0 (/ISS) E1C1L6 (/ISS) O75356 (/ISS) O75356 (/ISS) Q6P6S9 (/ISS) Q9QYC8 (/ISS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 O75356 (/IPI) O75356 (/IPI)
Guanosine-diphosphatase activity GO:0004382
Catalysis of the reaction: GDP + H2O = GMP + phosphate.
1 Q9WUZ9 (/IDA)
Guanosine-5'-triphosphate,3'-diphosphate diphosphatase activity GO:0008894
Catalysis of the reaction: guanosine 5'-triphosphate,3'-diphosphate + H2O = guanosine 5'-diphosphate,3'-diphosphate + phosphate.
1 Q9ER31 (/IDA)
Guanosine-5'-triphosphate,3'-diphosphate diphosphatase activity GO:0008894
Catalysis of the reaction: guanosine 5'-triphosphate,3'-diphosphate + H2O = guanosine 5'-diphosphate,3'-diphosphate + phosphate.
1 Q3U0P5 (/ISO)
Nucleoside-diphosphatase activity GO:0017110
Catalysis of the reaction: a nucleoside diphosphate + H2O = a nucleotide + phosphate.
1 Q9ER31 (/IDA)
Nucleoside-diphosphatase activity GO:0017110
Catalysis of the reaction: a nucleoside diphosphate + H2O = a nucleotide + phosphate.
1 Q3U0P5 (/ISO)
Nucleoside-triphosphatase activity GO:0017111
Catalysis of the reaction: a nucleoside triphosphate + H2O = nucleoside diphosphate + phosphate.
1 Q9ER31 (/IDA)
Nucleoside-triphosphatase activity GO:0017111
Catalysis of the reaction: a nucleoside triphosphate + H2O = nucleoside diphosphate + phosphate.
1 Q3U0P5 (/ISO)
Uridine-diphosphatase activity GO:0045134
Catalysis of the reaction: UDP + H2O = UMP + phosphate.
1 Q9WUZ9 (/IDA)

There are 19 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein N-linked glycosylation GO:0006487
A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via the N4 atom of peptidyl-asparagine, the omega-N of arginine, or the N1' atom peptidyl-tryptophan.
7 D2GZV9 (/ISS) E1BPW0 (/ISS) E1C1L6 (/ISS) O75356 (/ISS) O75356 (/ISS) Q6P6S9 (/ISS) Q9QYC8 (/ISS)
Cell population proliferation GO:0008283
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
7 D2GZV9 (/ISS) E1BPW0 (/ISS) E1C1L6 (/ISS) O75356 (/ISS) O75356 (/ISS) Q6P6S9 (/ISS) Q9QYC8 (/ISS)
Regulation of phosphatidylinositol 3-kinase signaling GO:0014066
Any process that modulates the frequency, rate or extent of signal transduction mediated by the phosphatidylinositol 3-kinase cascade.
7 D2GZV9 (/ISS) E1BPW0 (/ISS) E1C1L6 (/ISS) O75356 (/ISS) O75356 (/ISS) Q6P6S9 (/ISS) Q9QYC8 (/ISS)
Positive regulation of glycolytic process GO:0045821
Any process that activates or increases the frequency, rate or extent of glycolysis.
7 D2GZV9 (/ISS) E1BPW0 (/ISS) E1C1L6 (/ISS) O75356 (/ISS) O75356 (/ISS) Q6P6S9 (/ISS) Q9QYC8 (/ISS)
ATP metabolic process GO:0046034
The chemical reactions and pathways involving ATP, adenosine triphosphate, a universally important coenzyme and enzyme regulator.
7 D2GZV9 (/ISS) E1BPW0 (/ISS) E1C1L6 (/ISS) O75356 (/ISS) O75356 (/ISS) Q6P6S9 (/ISS) Q9QYC8 (/ISS)
'de novo' posttranslational protein folding GO:0051084
The process of assisting in the correct noncovalent folding of newly formed polypeptides or folding intermediates of polypeptides that have exited the ribosome and/or have been stabilized and transferred by other chaperone proteins. This process could involve several cycles of ATP hydrolysis.
7 D2GZV9 (/ISS) E1BPW0 (/ISS) E1C1L6 (/ISS) O75356 (/ISS) O75356 (/ISS) Q6P6S9 (/ISS) Q9QYC8 (/ISS)
Nucleobase-containing small molecule catabolic process GO:0034656
The chemical reactions and pathways resulting in the breakdown of a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide.
3 O75354 (/TAS) O75356 (/TAS) O75356 (/TAS)
Protein N-linked glycosylation GO:0006487
A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via the N4 atom of peptidyl-asparagine, the omega-N of arginine, or the N1' atom peptidyl-tryptophan.
1 Q9WUZ9 (/IMP)
Cell population proliferation GO:0008283
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
1 Q9WUZ9 (/IMP)
Regulation of phosphatidylinositol 3-kinase signaling GO:0014066
Any process that modulates the frequency, rate or extent of signal transduction mediated by the phosphatidylinositol 3-kinase cascade.
1 Q9WUZ9 (/IMP)
Bone mineralization GO:0030282
The deposition of hydroxyapatite, a form of calcium phosphate with the formula Ca10(PO4)6(OH)2, in bone tissue.
1 E7F8A7 (/IMP)
Response to magnesium ion GO:0032026
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnesium ion stimulus.
1 Q9ER31 (/IDA)
Response to magnesium ion GO:0032026
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnesium ion stimulus.
1 Q3U0P5 (/ISO)
Positive regulation of glycolytic process GO:0045821
Any process that activates or increases the frequency, rate or extent of glycolysis.
1 Q9WUZ9 (/IMP)
ATP metabolic process GO:0046034
The chemical reactions and pathways involving ATP, adenosine triphosphate, a universally important coenzyme and enzyme regulator.
1 Q9WUZ9 (/IMP)
'de novo' posttranslational protein folding GO:0051084
The process of assisting in the correct noncovalent folding of newly formed polypeptides or folding intermediates of polypeptides that have exited the ribosome and/or have been stabilized and transferred by other chaperone proteins. This process could involve several cycles of ATP hydrolysis.
1 Q9WUZ9 (/IMP)
Response to calcium ion GO:0051592
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.
1 Q9ER31 (/IDA)
Response to calcium ion GO:0051592
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.
1 Q3U0P5 (/ISO)
Phosphate ion homeostasis GO:0055062
Any process involved in the maintenance of an internal steady state of phosphate ions within an organism or cell.
1 E7F8A7 (/IMP)

There are 11 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
7 D2GZV9 (/ISS) E1BPW0 (/ISS) E1C1L6 (/ISS) O75356 (/ISS) O75356 (/ISS) Q6P6S9 (/ISS) Q9QYC8 (/ISS)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
3 O75354 (/TAS) O75356 (/TAS) O75356 (/TAS)
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
2 O75354 (/IDA) Q9ER31 (/IDA)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
1 Q9ER31 (/IDA)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
1 Q3U0P5 (/ISO)
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
1 Q9WUZ9 (/IDA)
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
1 Q3U0P5 (/ISO)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q9ER31 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q3U0P5 (/ISO)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
1 Q9ER31 (/IDA)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
1 Q3U0P5 (/ISO)
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