The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Sulfite Reductase Hemoprotein, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
SC:1Sulfite reductase [NADPH] hemoprotein beta-componentSulfite reductase [ferredoxin], chloroplasticSulfite reductase [ferredoxin]Sulfite reductase [ferredoxin]Sulfite reductase [ferredoxin], chloroplasticSC:2Sulfite reductase [NADPH] hemoprotein beta-component4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin)4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin)4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin)4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin)4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin)Nitrite reductase [NAD(P)H] large subunitNitrite reductase large subunitAnaerobic sulfite reductase subunit AsrC4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin)Sulfite reductase subunit betaNitrite reductase large subunitNitrite/sulfite reductase, 4Fe-4S iron-sulfur cluster-binding domain proteinNitrite/sulfite reductase, 4Fe-4S iron-sulfur cluster-binding domain proteinSulfite reductaseNitrite reductaseSulfite reductase, dissimilatory-type beta subunit4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin)Nitrite reductaseNitrite reductase (NAD(P)H) large subunitSulfite reductase-related proteinSulfite reductase (NADPH)Nitrite and sulphite reductase 4Fe-4S regionSulfite reductase hemoprotein beta component (CysI)Sulfite reductase, assimilatoryNitrite and sulphite reductase 4Fe-4S regionAnaerobic sulfite reductase subunit c4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin)Nitrite/sulfite reductase domain proteinPrecorrin-3B synthaseAssimilatory ferredoxin-dependent nitrite reductaseAnaerobic sulfite reductase subunit CProbable oxidoreductaseSulfite reductase [NADPH] subunit betaSulfite reductase [ferredoxin], chloroplastic
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FunFam 23: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate syntha...

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC TermAnnotationsEvidence
(E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (flavodoxin). [EC: 1.17.7.3]
(E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + H(2)O + oxidized flavodoxin = 2-C-methyl-D-erythritol 2,4-cyclodiphosphate + reduced flavodoxin.
  • Forms part of an alternative non-mevalonate pathway for isoprenoid biosynthesis that is found in most bacteria.
  • Plants and cyanobacteria have a similar enzyme that utilizes ferredoxin rather than flavodoxin (cf. EC 1.17.7.1).
20 A0A101EQZ3 A0A101EQZ3 A0A101EQZ3 A0A101EQZ3 A0A124FJH4 A0A124FJH4 A0A124FJH4 A0A124FJH4 A5IIP2 A5IIP2
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