The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Zinc/RING finger domain, C3HC4 (zinc finger)
".
FunFam 759: COMPASS component SPP1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
|
6 | Q03012 (/IDA) Q03012 (/IDA) Q03012 (/IDA) Q03012 (/IDA) Q03012 (/IDA) Q03012 (/IDA) |
|
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
|
6 | Q03012 (/IMP) Q03012 (/IMP) Q03012 (/IMP) Q03012 (/IMP) Q03012 (/IMP) Q03012 (/IMP) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
6 | Q03012 (/IPI) Q03012 (/IPI) Q03012 (/IPI) Q03012 (/IPI) Q03012 (/IPI) Q03012 (/IPI) |
|
Methylated histone binding GO:0035064
Interacting selectively and non-covalently with a histone in which a residue has been modified by methylation. Histones are any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes.
|
6 | Q03012 (/IDA) Q03012 (/IDA) Q03012 (/IDA) Q03012 (/IDA) Q03012 (/IDA) Q03012 (/IDA) |
There are 7 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Chromatin silencing at telomere GO:0006348
Repression of transcription of telomeric DNA by altering the structure of chromatin.
|
6 | Q03012 (/IMP) Q03012 (/IMP) Q03012 (/IMP) Q03012 (/IMP) Q03012 (/IMP) Q03012 (/IMP) |
|
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
6 | Q03012 (/IMP) Q03012 (/IMP) Q03012 (/IMP) Q03012 (/IMP) Q03012 (/IMP) Q03012 (/IMP) |
|
Histone H3-K4 methylation GO:0051568
The modification of histone H3 by addition of one or more methyl groups to lysine at position 4 of the histone.
|
6 | Q03012 (/IDA) Q03012 (/IDA) Q03012 (/IDA) Q03012 (/IDA) Q03012 (/IDA) Q03012 (/IDA) |
|
Histone H3-K4 methylation GO:0051568
The modification of histone H3 by addition of one or more methyl groups to lysine at position 4 of the histone.
|
6 | Q03012 (/IMP) Q03012 (/IMP) Q03012 (/IMP) Q03012 (/IMP) Q03012 (/IMP) Q03012 (/IMP) |
|
Regulation of meiotic DNA double-strand break formation GO:1903341
Any process that modulates the frequency, rate or extent of meiotic DNA double-strand break formation.
|
6 | Q03012 (/IMP) Q03012 (/IMP) Q03012 (/IMP) Q03012 (/IMP) Q03012 (/IMP) Q03012 (/IMP) |
|
Regulation of histone H3-K4 methylation GO:0051569
Any process that modulates the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 4 of histone H3.
|
1 | O74508 (/IMP) |
|
Heterochromatin assembly involved in chromatin silencing GO:0070869
Any process that results in the assembly of chromatin into heterochromatin and contributes to chromatin silencing.
|
1 | O74508 (/IC) |
There are 7 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
6 | Q03012 (/IDA) Q03012 (/IDA) Q03012 (/IDA) Q03012 (/IDA) Q03012 (/IDA) Q03012 (/IDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
6 | Q03012 (/IDA) Q03012 (/IDA) Q03012 (/IDA) Q03012 (/IDA) Q03012 (/IDA) Q03012 (/IDA) |
|
Set1C/COMPASS complex GO:0048188
A conserved protein complex that catalyzes methylation of histone H3. In Saccharomyces the complex contains Shg1p, Sdc1p, Swd1p, Swd2p, Swd3p, Spp1p, Bre2p, and the trithorax-related Set1p; in mammals it contains the catalytic subunit (SETD1A or SETD1B), WDR5, WDR82, RBBP5, ASH2L/ASH2, CXXC1/CFP1, HCFC1 and DPY30.
|
6 | Q03012 (/IPI) Q03012 (/IPI) Q03012 (/IPI) Q03012 (/IPI) Q03012 (/IPI) Q03012 (/IPI) |
|
Nuclear chromatin GO:0000790
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus.
|
1 | O74508 (/IC) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | O74508 (/HDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | O74508 (/HDA) |
|
Set1C/COMPASS complex GO:0048188
A conserved protein complex that catalyzes methylation of histone H3. In Saccharomyces the complex contains Shg1p, Sdc1p, Swd1p, Swd2p, Swd3p, Spp1p, Bre2p, and the trithorax-related Set1p; in mammals it contains the catalytic subunit (SETD1A or SETD1B), WDR5, WDR82, RBBP5, ASH2L/ASH2, CXXC1/CFP1, HCFC1 and DPY30.
|
1 | O74508 (/IDA) |
