The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Zinc/RING finger domain, C3HC4 (zinc finger)
".
FunFam 199: Bromodomain adjacent to zinc finger domain 2B
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
7 | A0A0B4KEM1 (/IPI) A0A0B4KFE3 (/IPI) A1Z8M2 (/IPI) A8DYA3 (/IPI) Q960I3 (/IPI) Q9BMQ0 (/IPI) Q9UIF8 (/IPI) |
|
Transcription factor binding GO:0008134
Interacting selectively and non-covalently with a transcription factor, a protein required to initiate or regulate transcription.
|
6 | A0A0B4KEM1 (/IPI) A0A0B4KFE3 (/IPI) A1Z8M2 (/IPI) A8DYA3 (/IPI) Q960I3 (/IPI) Q9BMQ0 (/IPI) |
|
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
1 | B7ZS37 (/ISS) |
|
Lysine-acetylated histone binding GO:0070577
Interacting selectively and non-covalently with a histone in which a lysine residue has been modified by acetylation.
|
1 | B7ZS37 (/ISS) |
There are 8 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nervous system development GO:0007399
The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.
|
6 | A0A0B4KEM1 (/IMP) A0A0B4KFE3 (/IMP) A1Z8M2 (/IMP) A8DYA3 (/IMP) Q960I3 (/IMP) Q9BMQ0 (/IMP) |
|
ATP-dependent chromatin remodeling GO:0043044
Dynamic structural changes to eukaryotic chromatin that require energy from the hydrolysis of ATP, ranging from local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation, mediated by ATP-dependent chromatin-remodelling factors.
|
6 | A0A0B4KEM1 (/IDA) A0A0B4KFE3 (/IDA) A1Z8M2 (/IDA) A8DYA3 (/IDA) Q960I3 (/IDA) Q9BMQ0 (/IDA) |
|
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
6 | A0A0B4KEM1 (/IMP) A0A0B4KFE3 (/IMP) A1Z8M2 (/IMP) A8DYA3 (/IMP) Q960I3 (/IMP) Q9BMQ0 (/IMP) |
|
Chromatin silencing at rDNA GO:0000183
Repression of transcription of ribosomal DNA by altering the structure of chromatin.
|
1 | B7ZS37 (/ISS) |
|
DNA methylation GO:0006306
The covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine.
|
1 | B7ZS37 (/ISS) |
|
Chromatin remodeling GO:0006338
Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation.
|
1 | Q9UIF8 (/TAS) |
|
Regulation of transcription by RNA polymerase II GO:0006357
Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
1 | Q9UIF8 (/NAS) |
|
Histone deacetylation GO:0016575
The modification of histones by removal of acetyl groups.
|
1 | B7ZS37 (/ISS) |
There are 4 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
ISWI-type complex GO:0031010
Any nuclear protein complex that contains an ATPase subunit of the imitation switch (ISWI) family. ISWI ATPases are involved in assembling chromatin and in sliding and spacing nucleosomes to regulate transcription of nuclear RNA polymerases I, II, and III and also DNA replication, recombination and repair.
|
6 | A0A0B4KEM1 (/IDA) A0A0B4KFE3 (/IDA) A1Z8M2 (/IDA) A8DYA3 (/IDA) Q960I3 (/IDA) Q9BMQ0 (/IDA) |
|
Chromatin silencing complex GO:0005677
Any protein complex that mediates changes in chromatin structure that result in transcriptional silencing.
|
1 | B7ZS37 (/ISS) |
|
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
|
1 | B7ZS37 (/ISS) |
|
RDNA heterochromatin GO:0033553
A region of heterochromatin located at the rDNA repeats in a chromosome.
|
1 | B7ZS37 (/ISS) |
