The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Zinc/RING finger domain, C3HC4 (zinc finger)
".
FunFam 144: Tripartite motif-containing 5 (Predicted)
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 25 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Ubiquitin-protein transferase activity GO:0004842
Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.
|
37 |
Q0PF16 (/ISS)
Q1ACD5 (/ISS)
Q1ACD6 (/ISS)
Q1ACD7 (/ISS)
Q1ACD8 (/ISS)
Q2YEM8 (/ISS)
Q2YEM9 (/ISS)
Q2YEN0 (/ISS)
Q2YEN2 (/ISS)
Q3ZEE5 (/ISS)
(27 more) |
Signaling pattern recognition receptor activity GO:0008329
Combining with a pathogen-associated molecular pattern (PAMP), a structure conserved among microbial species, or damage-associated molecular pattern (DAMP), an endogenous molecule released from damaged cells), and transmitting a signal to initiate a change in cell activity.
|
35 |
Q0PF16 (/ISS)
Q1ACD5 (/ISS)
Q1ACD6 (/ISS)
Q1ACD7 (/ISS)
Q1ACD8 (/ISS)
Q2YEM8 (/ISS)
Q2YEM9 (/ISS)
Q2YEN0 (/ISS)
Q2YEN2 (/ISS)
Q3ZEE5 (/ISS)
(25 more) |
Ubiquitin-protein transferase activity GO:0004842
Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.
|
7 | D3YYU4 (/ISO) D3Z3L3 (/ISO) E9PV98 (/ISO) Q62191 (/ISO) Q6P6F6 (/ISO) Q8CC73 (/ISO) Q8CHU6 (/ISO) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
7 | P19474 (/IPI) P19474 (/IPI) Q0PF16 (/IPI) Q62191 (/IPI) Q8IYM9 (/IPI) Q9C030 (/IPI) Q9C035 (/IPI) |
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
|
7 | D3YYU4 (/ISO) D3Z3L3 (/ISO) E9PV98 (/ISO) Q6P6F6 (/ISO) Q8BGE7 (/ISO) Q8CC73 (/ISO) Q8CHU6 (/ISO) |
Protein binding, bridging GO:0030674
The binding activity of a molecule that brings together two or more protein molecules, or a protein and another macromolecule or complex, through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way.
|
7 | D3YYU4 (/ISO) D3Z3L3 (/ISO) E9PV98 (/ISO) Q6P6F6 (/ISO) Q8BGE7 (/ISO) Q8CC73 (/ISO) Q8CHU6 (/ISO) |
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
7 | D3YYU4 (/ISO) D3Z3L3 (/ISO) E9PV98 (/ISO) Q62191 (/ISO) Q6P6F6 (/ISO) Q8CC73 (/ISO) Q8CHU6 (/ISO) |
Signaling pattern recognition receptor activity GO:0008329
Combining with a pathogen-associated molecular pattern (PAMP), a structure conserved among microbial species, or damage-associated molecular pattern (DAMP), an endogenous molecule released from damaged cells), and transmitting a signal to initiate a change in cell activity.
|
6 | D3YYU4 (/ISO) D3Z3L3 (/ISO) E9PV98 (/ISO) Q6P6F6 (/ISO) Q8CC73 (/ISO) Q8CHU6 (/ISO) |
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
6 | D3YYU4 (/ISO) D3Z3L3 (/ISO) E9PV98 (/ISO) Q6P6F6 (/ISO) Q8CC73 (/ISO) Q8CHU6 (/ISO) |
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
|
4 | Q8BGE7 (/IPI) Q8IYM9 (/IPI) Q9C030 (/IPI) Q9C035 (/IPI) |
Showing 1 to 10 of 25 entries
There are 103 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Activation of innate immune response GO:0002218
Any process that initiates an innate immune response. Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens. Examples of this process include activation of the hypersensitive response of Arabidopsis thaliana and activation of any NOD or TLR signaling pathway in vertebrate species.
|
35 |
Q0PF16 (/ISS)
Q1ACD5 (/ISS)
Q1ACD6 (/ISS)
Q1ACD7 (/ISS)
Q1ACD8 (/ISS)
Q2YEM8 (/ISS)
Q2YEM9 (/ISS)
Q2YEN0 (/ISS)
Q2YEN2 (/ISS)
Q3ZEE5 (/ISS)
(25 more) |
Regulation of lipopolysaccharide-mediated signaling pathway GO:0031664
Any process that modulates the frequency, rate or extent of signaling in response to detection of lipopolysaccharide.
|
35 |
Q0PF16 (/ISS)
Q1ACD5 (/ISS)
Q1ACD6 (/ISS)
Q1ACD7 (/ISS)
Q1ACD8 (/ISS)
Q2YEM8 (/ISS)
Q2YEM9 (/ISS)
Q2YEN0 (/ISS)
Q2YEN2 (/ISS)
Q3ZEE5 (/ISS)
(25 more) |
Positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123
Any process that activates or increases the frequency, rate or extent of I-kappaB kinase/NF-kappaB signaling.
|
35 |
Q0PF16 (/ISS)
Q1ACD5 (/ISS)
Q1ACD6 (/ISS)
Q1ACD7 (/ISS)
Q1ACD8 (/ISS)
Q2YEM8 (/ISS)
Q2YEM9 (/ISS)
Q2YEN0 (/ISS)
Q2YEN2 (/ISS)
Q3ZEE5 (/ISS)
(25 more) |
Positive regulation of MAPK cascade GO:0043410
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the MAPK cascade.
|
35 |
Q0PF16 (/ISS)
Q1ACD5 (/ISS)
Q1ACD6 (/ISS)
Q1ACD7 (/ISS)
Q1ACD8 (/ISS)
Q2YEM8 (/ISS)
Q2YEM9 (/ISS)
Q2YEN0 (/ISS)
Q2YEN2 (/ISS)
Q3ZEE5 (/ISS)
(25 more) |
Positive regulation of NF-kappaB transcription factor activity GO:0051092
Any process that activates or increases the frequency, rate or extent of activity of the transcription factor NF-kappaB.
|
35 |
Q0PF16 (/ISS)
Q1ACD5 (/ISS)
Q1ACD6 (/ISS)
Q1ACD7 (/ISS)
Q1ACD8 (/ISS)
Q2YEM8 (/ISS)
Q2YEM9 (/ISS)
Q2YEN0 (/ISS)
Q2YEN2 (/ISS)
Q3ZEE5 (/ISS)
(25 more) |
Protein K63-linked ubiquitination GO:0070534
A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is added to a protein. K63-linked ubiquitination does not target the substrate protein for degradation, but is involved in several pathways, notably as a signal to promote error-free DNA postreplication repair.
|
35 |
Q0PF16 (/ISS)
Q1ACD5 (/ISS)
Q1ACD6 (/ISS)
Q1ACD7 (/ISS)
Q1ACD8 (/ISS)
Q2YEM8 (/ISS)
Q2YEM9 (/ISS)
Q2YEN0 (/ISS)
Q2YEN2 (/ISS)
Q3ZEE5 (/ISS)
(25 more) |
Defense response to virus GO:0051607
Reactions triggered in response to the presence of a virus that act to protect the cell or organism.
|
7 | Q0PF16 (/TAS) Q587N6 (/TAS) Q5C8U3 (/TAS) Q5C8U4 (/TAS) Q5D7I0 (/TAS) Q5D7I0 (/TAS) Q9C035 (/TAS) |
Positive regulation of DNA-binding transcription factor activity GO:0051091
Any process that activates or increases the frequency, rate or extent of activity of a transcription factor, any factor involved in the initiation or regulation of transcription.
|
5 | P19474 (/IDA) P19474 (/IDA) Q0PF16 (/IDA) Q8IYM9 (/IDA) Q9BYJ4 (/IDA) |
Interferon-gamma-mediated signaling pathway GO:0060333
A series of molecular signals initiated by the binding of interferon-gamma to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. Interferon gamma is the only member of the type II interferon found so far.
|
5 | P19474 (/TAS) P19474 (/TAS) Q8IYM9 (/TAS) Q9BYJ4 (/TAS) Q9C035 (/TAS) |
Protein trimerization GO:0070206
The formation of a protein trimer, a macromolecular structure consisting of three noncovalently associated identical or nonidentical subunits.
|
5 | P19474 (/IDA) P19474 (/IDA) Q8IYM9 (/IDA) Q9BYJ4 (/IDA) Q9C030 (/IDA) |
Showing 1 to 10 of 103 entries
There are 19 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
P-body GO:0000932
A focus in the cytoplasm where mRNAs may become inactivated by decapping or some other mechanism. Protein and RNA localized to these foci are involved in mRNA degradation, nonsense-mediated mRNA decay (NMD), translational repression, and RNA-mediated gene silencing.
|
34 |
Q1ACD5 (/ISS)
Q1ACD6 (/ISS)
Q1ACD7 (/ISS)
Q1ACD8 (/ISS)
Q2YEM8 (/ISS)
Q2YEM9 (/ISS)
Q2YEN0 (/ISS)
Q2YEN2 (/ISS)
Q3ZEE5 (/ISS)
Q587N6 (/ISS)
(24 more) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
10 | P15533 (/IDA) P19474 (/IDA) P19474 (/IDA) Q62191 (/IDA) Q8BGE7 (/IDA) Q8IYM9 (/IDA) Q99PQ1 (/IDA) Q9BYJ4 (/IDA) Q9C030 (/IDA) Q9C035 (/IDA) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
8 | D3YYU4 (/ISO) D3Z3L3 (/ISO) E9PV98 (/ISO) Q62191 (/ISO) Q6P6F6 (/ISO) Q8BGE7 (/ISO) Q8CC73 (/ISO) Q8CHU6 (/ISO) |
P-body GO:0000932
A focus in the cytoplasm where mRNAs may become inactivated by decapping or some other mechanism. Protein and RNA localized to these foci are involved in mRNA degradation, nonsense-mediated mRNA decay (NMD), translational repression, and RNA-mediated gene silencing.
|
6 | D3YYU4 (/ISO) D3Z3L3 (/ISO) E9PV98 (/ISO) Q6P6F6 (/ISO) Q8CC73 (/ISO) Q8CHU6 (/ISO) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
5 | P19474 (/TAS) P19474 (/TAS) Q8IYM9 (/TAS) Q9BYJ4 (/TAS) Q9C035 (/TAS) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
3 | P19474 (/IDA) P19474 (/IDA) Q8IYM9 (/IDA) |
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
3 | P19474 (/IDA) P19474 (/IDA) Q8IYM9 (/IDA) |
P-body GO:0000932
A focus in the cytoplasm where mRNAs may become inactivated by decapping or some other mechanism. Protein and RNA localized to these foci are involved in mRNA degradation, nonsense-mediated mRNA decay (NMD), translational repression, and RNA-mediated gene silencing.
|
2 | Q0PF16 (/IDA) Q9C035 (/IDA) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
2 | Q62191 (/ISS) Q7YRV4 (/ISS) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
2 | Q62191 (/ISS) Q7YRV4 (/ISS) |
Showing 1 to 10 of 19 entries