The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"TruD, catalytic domain
".
FunFam 2: Pseudouridylate synthase 7 homolog
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 7 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
3 | Q96PZ0 (/HDA) Q96PZ0 (/HDA) Q96PZ0 (/HDA) |
|
Pseudouridine synthase activity GO:0009982
Catalysis of the reaction: RNA uridine = RNA pseudouridine. Conversion of uridine in an RNA molecule to pseudouridine by rotation of the C1'-N-1 glycosidic bond of uridine in RNA to a C1'-C5.
|
3 | Q96PZ0 (/IDA) Q96PZ0 (/IDA) Q96PZ0 (/IDA) |
|
Pseudouridine synthase activity GO:0009982
Catalysis of the reaction: RNA uridine = RNA pseudouridine. Conversion of uridine in an RNA molecule to pseudouridine by rotation of the C1'-N-1 glycosidic bond of uridine in RNA to a C1'-C5.
|
3 | Q96PZ0 (/IMP) Q96PZ0 (/IMP) Q96PZ0 (/IMP) |
|
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
|
3 | Q96PZ0 (/IPI) Q96PZ0 (/IPI) Q96PZ0 (/IPI) |
|
Pseudouridine synthase activity GO:0009982
Catalysis of the reaction: RNA uridine = RNA pseudouridine. Conversion of uridine in an RNA molecule to pseudouridine by rotation of the C1'-N-1 glycosidic bond of uridine in RNA to a C1'-C5.
|
2 | Q08DI8 (/ISS) Q91VU7 (/ISS) |
|
Pseudouridine synthase activity GO:0009982
Catalysis of the reaction: RNA uridine = RNA pseudouridine. Conversion of uridine in an RNA molecule to pseudouridine by rotation of the C1'-N-1 glycosidic bond of uridine in RNA to a C1'-C5.
|
1 | Q91VU7 (/ISO) |
|
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
|
1 | Q91VU7 (/ISO) |
There are 15 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Negative regulation of translation GO:0017148
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.
|
3 | Q96PZ0 (/IDA) Q96PZ0 (/IDA) Q96PZ0 (/IDA) |
|
TRNA pseudouridine synthesis GO:0031119
The intramolecular conversion of uridine to pseudouridine in a tRNA molecule.
|
3 | Q96PZ0 (/IDA) Q96PZ0 (/IDA) Q96PZ0 (/IDA) |
|
Regulation of hematopoietic stem cell differentiation GO:1902036
Any process that modulates the frequency, rate or extent of hematopoietic stem cell differentiation.
|
3 | Q96PZ0 (/IMP) Q96PZ0 (/IMP) Q96PZ0 (/IMP) |
|
MRNA pseudouridine synthesis GO:1990481
The intramolecular conversion of uridine to pseudouridine in an mRNA molecule.
|
3 | Q96PZ0 (/IMP) Q96PZ0 (/IMP) Q96PZ0 (/IMP) |
|
Regulation of mesoderm development GO:2000380
Any process that modulates the frequency, rate or extent of mesoderm development.
|
3 | Q96PZ0 (/IMP) Q96PZ0 (/IMP) Q96PZ0 (/IMP) |
|
Negative regulation of translation GO:0017148
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.
|
2 | Q08DI8 (/ISS) Q91VU7 (/ISS) |
|
TRNA pseudouridine synthesis GO:0031119
The intramolecular conversion of uridine to pseudouridine in a tRNA molecule.
|
2 | Q08DI8 (/ISS) Q91VU7 (/ISS) |
|
Regulation of hematopoietic stem cell differentiation GO:1902036
Any process that modulates the frequency, rate or extent of hematopoietic stem cell differentiation.
|
2 | Q08DI8 (/ISS) Q91VU7 (/ISS) |
|
MRNA pseudouridine synthesis GO:1990481
The intramolecular conversion of uridine to pseudouridine in an mRNA molecule.
|
2 | Q08DI8 (/ISS) Q91VU7 (/ISS) |
|
Regulation of mesoderm development GO:2000380
Any process that modulates the frequency, rate or extent of mesoderm development.
|
2 | Q08DI8 (/ISS) Q91VU7 (/ISS) |
|
Negative regulation of translation GO:0017148
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.
|
1 | Q91VU7 (/ISO) |
|
TRNA pseudouridine synthesis GO:0031119
The intramolecular conversion of uridine to pseudouridine in a tRNA molecule.
|
1 | Q91VU7 (/ISO) |
|
Regulation of hematopoietic stem cell differentiation GO:1902036
Any process that modulates the frequency, rate or extent of hematopoietic stem cell differentiation.
|
1 | Q91VU7 (/ISO) |
|
MRNA pseudouridine synthesis GO:1990481
The intramolecular conversion of uridine to pseudouridine in an mRNA molecule.
|
1 | Q91VU7 (/ISO) |
|
Regulation of mesoderm development GO:2000380
Any process that modulates the frequency, rate or extent of mesoderm development.
|
1 | Q91VU7 (/ISO) |
There are 3 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
3 | Q96PZ0 (/IDA) Q96PZ0 (/IDA) Q96PZ0 (/IDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
2 | Q08DI8 (/ISS) Q91VU7 (/ISS) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q91VU7 (/ISO) |
