The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Pseudouridine synthase
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 5: Pseudouridine synthase

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
TRNA pseudouridine(32) synthase. [EC: 5.4.99.28]
tRNA uridine(32) = tRNA pseudouridine(32).
  • The dual-specificity enzyme also catalyzes the formation of pseudouridine(746) in 23S rRNA.
  • Cf. EC 5.4.99.29.
20087 A0A023YS34 A0A023YS34 A0A023YS34 A0A023YS34 A0A023YS34 A0A023YS34 A0A023YS34 A0A023YS34 A0A023YS34 A0A023YS34
(20077 more...)
23S rRNA pseudouridine(746) synthase. [EC: 5.4.99.29]
23S rRNA uridine(746) = 23S rRNA pseudouridine(746).
  • RluA is the sole protein responsible for the in vivo formation of 23S RNA pseudouridine(746).
  • The dual-specificity enzyme also catalyzes the formation of uridine(32) in tRNA.
  • Cf. EC 5.4.99.28.
20087 A0A023YS34 A0A023YS34 A0A023YS34 A0A023YS34 A0A023YS34 A0A023YS34 A0A023YS34 A0A023YS34 A0A023YS34 A0A023YS34
(20077 more...)
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