The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Penicillin-binding protein 1b domain
".
FunFam 2: Transcription-repair-coupling factor
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 7 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
|
7 | P30958 (/IDA) P30958 (/IDA) P30958 (/IDA) P30958 (/IDA) P30958 (/IDA) P30958 (/IDA) P30958 (/IDA) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
7 | P30958 (/IPI) P30958 (/IPI) P30958 (/IPI) P30958 (/IPI) P30958 (/IPI) P30958 (/IPI) P30958 (/IPI) |
|
DNA translocase activity GO:0015616
Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive movement along a single- or double-stranded DNA molecule.
|
7 | P30958 (/IDA) P30958 (/IDA) P30958 (/IDA) P30958 (/IDA) P30958 (/IDA) P30958 (/IDA) P30958 (/IDA) |
|
RNA polymerase core enzyme binding GO:0043175
Interacting selectively and non-covalently with an RNA polymerase core enzyme, containing a specific subunit composition defined as the core enzyme.
|
7 | P30958 (/IDA) P30958 (/IDA) P30958 (/IDA) P30958 (/IDA) P30958 (/IDA) P30958 (/IDA) P30958 (/IDA) |
|
Double-stranded DNA binding GO:0003690
Interacting selectively and non-covalently with double-stranded DNA.
|
6 | Q9KQW2 (/ISS) Q9KQW2 (/ISS) Q9KQW2 (/ISS) Q9KQW2 (/ISS) Q9KQW2 (/ISS) Q9KQW2 (/ISS) |
|
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
|
6 | Q9KQW2 (/ISS) Q9KQW2 (/ISS) Q9KQW2 (/ISS) Q9KQW2 (/ISS) Q9KQW2 (/ISS) Q9KQW2 (/ISS) |
|
ATPase activity GO:0016887
Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
|
6 | Q9KQW2 (/ISS) Q9KQW2 (/ISS) Q9KQW2 (/ISS) Q9KQW2 (/ISS) Q9KQW2 (/ISS) Q9KQW2 (/ISS) |
There are 6 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Transcription-coupled nucleotide-excision repair, DNA damage recognition GO:0000716
The identification of lesions on the actively transcribed strand of the DNA duplex as well as a small subset of lesions not recognized by the general nucleotide-excision repair pathway.
|
7 | P30958 (/IDA) P30958 (/IDA) P30958 (/IDA) P30958 (/IDA) P30958 (/IDA) P30958 (/IDA) P30958 (/IDA) |
|
DNA repair GO:0006281
The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
|
7 | P30958 (/IMP) P30958 (/IMP) P30958 (/IMP) P30958 (/IMP) P30958 (/IMP) P30958 (/IMP) P30958 (/IMP) |
|
Transcription-coupled nucleotide-excision repair GO:0006283
The nucleotide-excision repair process that carries out preferential repair of DNA lesions on the actively transcribed strand of the DNA duplex. In addition, the transcription-coupled nucleotide-excision repair pathway is required for the recognition and repair of a small subset of lesions that are not recognized by the global genome nucleotide excision repair pathway.
|
7 | P30958 (/IMP) P30958 (/IMP) P30958 (/IMP) P30958 (/IMP) P30958 (/IMP) P30958 (/IMP) P30958 (/IMP) |
|
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
7 | P30958 (/IDA) P30958 (/IDA) P30958 (/IDA) P30958 (/IDA) P30958 (/IDA) P30958 (/IDA) P30958 (/IDA) |
|
Cellular response to DNA damage stimulus GO:0006974
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
|
7 | P30958 (/IDA) P30958 (/IDA) P30958 (/IDA) P30958 (/IDA) P30958 (/IDA) P30958 (/IDA) P30958 (/IDA) |
|
DNA repair GO:0006281
The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
|
6 | Q9KQW2 (/ISS) Q9KQW2 (/ISS) Q9KQW2 (/ISS) Q9KQW2 (/ISS) Q9KQW2 (/ISS) Q9KQW2 (/ISS) |
There are 1 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
7 | P30958 (/IDA) P30958 (/IDA) P30958 (/IDA) P30958 (/IDA) P30958 (/IDA) P30958 (/IDA) P30958 (/IDA) |
