The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Phosphorylase Kinase; domain 1
".
FunFam 62: PHO system negative regulator
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 7 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
7 | O74456 (/IPI) P17157 (/IPI) P17157 (/IPI) P17157 (/IPI) P17157 (/IPI) P17157 (/IPI) P17157 (/IPI) |
Protein kinase activity GO:0004672
Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
|
6 | P17157 (/HDA) P17157 (/HDA) P17157 (/HDA) P17157 (/HDA) P17157 (/HDA) P17157 (/HDA) |
Cyclin-dependent protein serine/threonine kinase activity GO:0004693
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate. This reaction requires the binding of a regulatory cyclin subunit and full activity requires stimulatory phosphorylation by a CDK-activating kinase (CAK).
|
6 | P17157 (/IDA) P17157 (/IDA) P17157 (/IDA) P17157 (/IDA) P17157 (/IDA) P17157 (/IDA) |
Cyclin-dependent protein serine/threonine kinase activity GO:0004693
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate. This reaction requires the binding of a regulatory cyclin subunit and full activity requires stimulatory phosphorylation by a CDK-activating kinase (CAK).
|
6 | P17157 (/IMP) P17157 (/IMP) P17157 (/IMP) P17157 (/IMP) P17157 (/IMP) P17157 (/IMP) |
Cyclin-dependent protein serine/threonine kinase activity GO:0004693
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate. This reaction requires the binding of a regulatory cyclin subunit and full activity requires stimulatory phosphorylation by a CDK-activating kinase (CAK).
|
3 | G5EAZ1 (/ISS) G5EAZ1 (/ISS) G5EAZ1 (/ISS) |
Cyclin-dependent protein serine/threonine kinase activity GO:0004693
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate. This reaction requires the binding of a regulatory cyclin subunit and full activity requires stimulatory phosphorylation by a CDK-activating kinase (CAK).
|
1 | A0A1D8PDA6 (/IGI) |
Cyclin-dependent protein kinase activity GO:0097472
Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP. This reaction requires the binding of a regulatory cyclin subunit and full activity requires stimulatory phosphorylation by a CDK-activating kinase (CAK).
|
1 | O74456 (/TAS) |
There are 30 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Regulation of transcription involved in G1/S transition of mitotic cell cycle GO:0000083
Any process that regulates transcription such that the target genes are involved in the transition between G1 and S phase of the mitotic cell cycle.
|
7 | O74456 (/IGI) P17157 (/IGI) P17157 (/IGI) P17157 (/IGI) P17157 (/IGI) P17157 (/IGI) P17157 (/IGI) |
Regulation of transcription involved in G1/S transition of mitotic cell cycle GO:0000083
Any process that regulates transcription such that the target genes are involved in the transition between G1 and S phase of the mitotic cell cycle.
|
6 | P17157 (/HGI) P17157 (/HGI) P17157 (/HGI) P17157 (/HGI) P17157 (/HGI) P17157 (/HGI) |
Regulation of transcription involved in G1/S transition of mitotic cell cycle GO:0000083
Any process that regulates transcription such that the target genes are involved in the transition between G1 and S phase of the mitotic cell cycle.
|
6 | P17157 (/IMP) P17157 (/IMP) P17157 (/IMP) P17157 (/IMP) P17157 (/IMP) P17157 (/IMP) |
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
6 | P17157 (/IGI) P17157 (/IGI) P17157 (/IGI) P17157 (/IGI) P17157 (/IGI) P17157 (/IGI) |
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
|
6 | P17157 (/HDA) P17157 (/HDA) P17157 (/HDA) P17157 (/HDA) P17157 (/HDA) P17157 (/HDA) |
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
|
6 | P17157 (/IDA) P17157 (/IDA) P17157 (/IDA) P17157 (/IDA) P17157 (/IDA) P17157 (/IDA) |
Cellular response to DNA damage stimulus GO:0006974
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
|
6 | P17157 (/IGI) P17157 (/IGI) P17157 (/IGI) P17157 (/IGI) P17157 (/IGI) P17157 (/IGI) |
Cellular response to DNA damage stimulus GO:0006974
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
|
6 | P17157 (/IMP) P17157 (/IMP) P17157 (/IMP) P17157 (/IMP) P17157 (/IMP) P17157 (/IMP) |
Positive regulation of macroautophagy GO:0016239
Any process, such as recognition of nutrient depletion, that activates or increases the rate of macroautophagy to bring cytosolic macromolecules to the vacuole/lysosome for degradation.
|
6 | P17157 (/IMP) P17157 (/IMP) P17157 (/IMP) P17157 (/IMP) P17157 (/IMP) P17157 (/IMP) |
Negative regulation of macroautophagy GO:0016242
Any process that stops, prevents, or reduces the frequency, rate or extent of macroautophagy.
|
6 | P17157 (/IMP) P17157 (/IMP) P17157 (/IMP) P17157 (/IMP) P17157 (/IMP) P17157 (/IMP) |
Fungal-type cell wall organization GO:0031505
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the fungal-type cell wall.
|
6 | P17157 (/HGI) P17157 (/HGI) P17157 (/HGI) P17157 (/HGI) P17157 (/HGI) P17157 (/HGI) |
Regulation of protein stability GO:0031647
Any process that affects the structure and integrity of a protein, altering the likelihood of its degradation or aggregation.
|
6 | P17157 (/IGI) P17157 (/IGI) P17157 (/IGI) P17157 (/IGI) P17157 (/IGI) P17157 (/IGI) |
Regulation of protein stability GO:0031647
Any process that affects the structure and integrity of a protein, altering the likelihood of its degradation or aggregation.
|
6 | P17157 (/IMP) P17157 (/IMP) P17157 (/IMP) P17157 (/IMP) P17157 (/IMP) P17157 (/IMP) |
Regulation of establishment or maintenance of cell polarity GO:0032878
Any process that modulates the frequency, rate or extent of the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns.
|
6 | P17157 (/IGI) P17157 (/IGI) P17157 (/IGI) P17157 (/IGI) P17157 (/IGI) P17157 (/IGI) |
Regulation of protein localization GO:0032880
Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location.
|
6 | P17157 (/IDA) P17157 (/IDA) P17157 (/IDA) P17157 (/IDA) P17157 (/IDA) P17157 (/IDA) |
Negative regulation of DNA-binding transcription factor activity GO:0043433
Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription.
|
6 | P17157 (/IGI) P17157 (/IGI) P17157 (/IGI) P17157 (/IGI) P17157 (/IGI) P17157 (/IGI) |
Negative regulation of DNA-binding transcription factor activity GO:0043433
Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription.
|
6 | P17157 (/IMP) P17157 (/IMP) P17157 (/IMP) P17157 (/IMP) P17157 (/IMP) P17157 (/IMP) |
Negative regulation of glycogen biosynthetic process GO:0045719
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen.
|
6 | P17157 (/IMP) P17157 (/IMP) P17157 (/IMP) P17157 (/IMP) P17157 (/IMP) P17157 (/IMP) |
Negative regulation of phosphate metabolic process GO:0045936
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving phosphates.
|
6 | P17157 (/IGI) P17157 (/IGI) P17157 (/IGI) P17157 (/IGI) P17157 (/IGI) P17157 (/IGI) |
Negative regulation of calcium-mediated signaling GO:0050849
Any process that stops, prevents, or reduces the frequency, rate or extent of calcium-mediated signaling.
|
6 | P17157 (/IGI) P17157 (/IGI) P17157 (/IGI) P17157 (/IGI) P17157 (/IGI) P17157 (/IGI) |
Positive regulation of phospholipid biosynthetic process GO:0071073
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phospholipids.
|
6 | P17157 (/IDA) P17157 (/IDA) P17157 (/IDA) P17157 (/IDA) P17157 (/IDA) P17157 (/IDA) |
Sporocarp development involved in sexual reproduction GO:0000909
The process whose specific outcome is the progression of a fruiting body organ over time, from its formation to the mature structure. The fruiting body is a spore bearing structure. In fungi, the sporocarp (also known as fruiting body) is a multicellular structure on which spore-producing structures, such as basidia or asci, are borne. The fruiting body is part of the sexual phase of a fungal life cycle, with the rest of the life cycle being characterized by vegetative mycelial growth. The sporocarp of a basidiomycete is known as a basidiocarp, while the fruiting body of an ascomycete is known as an ascocarp. A significant range of different shapes and morphologies is found in both basidiocarps and ascocarps; these features play an important role in the identification and taxonomy of fungi.
|
3 | G5EAZ1 (/IMP) G5EAZ1 (/IMP) G5EAZ1 (/IMP) |
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
|
3 | G5EAZ1 (/ISS) G5EAZ1 (/ISS) G5EAZ1 (/ISS) |
Conidium formation GO:0048315
The process of producing non-motile spores, called conidia, via mitotic asexual reproduction in higher fungi. Conidia are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus.
|
3 | G5EAZ1 (/IMP) G5EAZ1 (/IMP) G5EAZ1 (/IMP) |
Regulation of conidium formation GO:0075306
Any process that modulates the frequency, rate or extent of conidium formation, a process of producing non-motile spores, called conidia, via mitotic asexual reproduction in higher fungi. Conidia are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus.
|
3 | G5EAZ1 (/IMP) G5EAZ1 (/IMP) G5EAZ1 (/IMP) |
Phosphate-containing compound metabolic process GO:0006796
The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid.
|
1 | A0A1D8PDA6 (/IGI) |
Traversing start control point of mitotic cell cycle GO:0007089
A cell cycle process by which a cell commits to entering S phase via a positive feedback mechanism between the regulation of transcription and G1 CDK activity.
|
1 | O74456 (/IGI) |
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
|
1 | O74456 (/IC) |
Filamentous growth GO:0030447
The process in which a multicellular organism, a unicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.
|
1 | A0A1D8PDA6 (/IMP) |
Filamentous growth of a population of unicellular organisms in response to chemical stimulus GO:0036171
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a chemical stimulus.
|
1 | A0A1D8PDA6 (/IMP) |
There are 6 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Cyclin-dependent protein kinase holoenzyme complex GO:0000307
Cyclin-dependent protein kinases (CDKs) are enzyme complexes that contain a kinase catalytic subunit associated with a regulatory cyclin partner.
|
6 | P17157 (/IPI) P17157 (/IPI) P17157 (/IPI) P17157 (/IPI) P17157 (/IPI) P17157 (/IPI) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
6 | P17157 (/IDA) P17157 (/IDA) P17157 (/IDA) P17157 (/IDA) P17157 (/IDA) P17157 (/IDA) |
Pho85-Pho80 CDK-cyclin complex GO:1990860
A cyclin dependent kinase (CDK) complex that contains a kinase subunit and a regulatory cyclin subunit. An example of this complex in budding yeast S. cerevisiae consists of the Pho85 kinase and the Pho80 cyclin.
|
6 | P17157 (/IDA) P17157 (/IDA) P17157 (/IDA) P17157 (/IDA) P17157 (/IDA) P17157 (/IDA) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | O74456 (/HDA) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | O74456 (/HDA) |
Ascospore-type prospore GO:0042764
An immature spore undergoing development. The spore usually consists of nucleic acid, prospore membrane(s) that encase the nucleic acid, and ultimately a cell wall that covers the membrane(s). This type of spore is observed in ascospore-forming fungi.
|
1 | O74456 (/IDA) |