The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Classic Zinc Finger
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 515: early growth response protein 4

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
1 Q05215 (/ISA)
DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to activate or increase transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
1 Q05215 (/IC)
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
1 Q05215 (/NAS)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
1 Q05215 (/IDA)

There are 14 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Germ-band shortening GO:0007390
The spreading of the amnioserosa from its compressed state to cover the whole of the dorsal surface. Initiating in the thorax and spreading posteriorly, it is accompanied by the transition from a parasegmental to segmental division of the embryo.
7 A0A0B4KGW2 (/IMP) E1JIP0 (/IMP) Q24163 (/IMP) Q26452 (/IMP) Q7JP26 (/IMP) Q8IN91 (/IMP) Q9VED3 (/IMP)
Ectoderm development GO:0007398
The process whose specific outcome is the progression of the ectoderm over time, from its formation to the mature structure. In animal embryos, the ectoderm is the outer germ layer of the embryo, formed during gastrulation.
7 A0A0B4KGW2 (/IMP) E1JIP0 (/IMP) Q24163 (/IMP) Q26452 (/IMP) Q7JP26 (/IMP) Q8IN91 (/IMP) Q9VED3 (/IMP)
Central nervous system development GO:0007417
The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.
7 A0A0B4KGW2 (/IMP) E1JIP0 (/IMP) Q24163 (/IMP) Q26452 (/IMP) Q7JP26 (/IMP) Q8IN91 (/IMP) Q9VED3 (/IMP)
Epithelial cell migration, open tracheal system GO:0007427
The orderly movement of epithelial cells during development of an open tracheal system. An example of this is found in Drosophila melanogaster.
7 A0A0B4KGW2 (/IGI) E1JIP0 (/IGI) Q24163 (/IGI) Q26452 (/IGI) Q7JP26 (/IGI) Q8IN91 (/IGI) Q9VED3 (/IGI)
Epithelial cell migration, open tracheal system GO:0007427
The orderly movement of epithelial cells during development of an open tracheal system. An example of this is found in Drosophila melanogaster.
7 A0A0B4KGW2 (/IMP) E1JIP0 (/IMP) Q24163 (/IMP) Q26452 (/IMP) Q7JP26 (/IMP) Q8IN91 (/IMP) Q9VED3 (/IMP)
Muscle organ development GO:0007517
The process whose specific outcome is the progression of the muscle over time, from its formation to the mature structure. The muscle is an organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work.
7 A0A0B4KGW2 (/IMP) E1JIP0 (/IMP) Q24163 (/IMP) Q26452 (/IMP) Q7JP26 (/IMP) Q8IN91 (/IMP) Q9VED3 (/IMP)
Somatic muscle development GO:0007525
The process whose specific outcome is the progression of the somatic muscle over time, from its formation to the mature structure. Somatic muscles are striated muscle structures that connect to the exoskeleton or cuticle.
7 A0A0B4KGW2 (/IMP) E1JIP0 (/IMP) Q24163 (/IMP) Q26452 (/IMP) Q7JP26 (/IMP) Q8IN91 (/IMP) Q9VED3 (/IMP)
Determination of muscle attachment site GO:0016204
The process that mediates the transfer of information from the cells of a muscle to those of its intended target, thereby identifying the target site.
7 A0A0B4KGW2 (/TAS) E1JIP0 (/TAS) Q24163 (/TAS) Q26452 (/TAS) Q7JP26 (/TAS) Q8IN91 (/TAS) Q9VED3 (/TAS)
Pigment metabolic process GO:0042440
The chemical reactions and pathways involving pigment, any general or particular coloring matter in living organisms, e.g. melanin.
7 A0A0B4KGW2 (/TAS) E1JIP0 (/TAS) Q24163 (/TAS) Q26452 (/TAS) Q7JP26 (/TAS) Q8IN91 (/TAS) Q9VED3 (/TAS)
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
1 Q05215 (/TAS)
Negative regulation of MAP kinase activity GO:0043407
Any process that stops, prevents, or reduces the frequency, rate or extent of MAP kinase activity.
1 Q18250 (/IMP)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1 Q05215 (/IDA)
Negative regulation of ovulation GO:0060280
Any process that stops, prevents, or reduces the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary.
1 Q18250 (/IMP)
Negative regulation of oocyte maturation GO:1900194
Any process that stops, prevents or reduces the frequency, rate or extent of oocyte maturation.
1 Q18250 (/IMP)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q18250 (/IDA)
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
1 Q18250 (/IDA)
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