The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: 50S ribosomal protein L7/L12

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 9 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
250 P02394 (/IPI) P02394 (/IPI) P02394 (/IPI) P02394 (/IPI) P02394 (/IPI) P02394 (/IPI) P02394 (/IPI) P02394 (/IPI) P02394 (/IPI) P02394 (/IPI)
(240 more)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
183 P0A7K2 (/IDA) P0A7K2 (/IDA) P0A7K2 (/IDA) P0A7K2 (/IDA) P0A7K2 (/IDA) P0A7K2 (/IDA) P0A7K2 (/IDA) P0A7K2 (/IDA) P0A7K2 (/IDA) P0A7K2 (/IDA)
(173 more)
Ribosome binding GO:0043022
Interacting selectively and non-covalently with any part of a ribosome.
183 P0A7K2 (/IDA) P0A7K2 (/IDA) P0A7K2 (/IDA) P0A7K2 (/IDA) P0A7K2 (/IDA) P0A7K2 (/IDA) P0A7K2 (/IDA) P0A7K2 (/IDA) P0A7K2 (/IDA) P0A7K2 (/IDA)
(173 more)
Structural constituent of ribosome GO:0003735
The action of a molecule that contributes to the structural integrity of the ribosome.
22 O96202 (/ISS) O96202 (/ISS) O96202 (/ISS) O96202 (/ISS) O96202 (/ISS) O96202 (/ISS) O96202 (/ISS) O96202 (/ISS) O96202 (/ISS) O96202 (/ISS)
(12 more)
Structural constituent of ribosome GO:0003735
The action of a molecule that contributes to the structural integrity of the ribosome.
7 P53163 (/IDA) P53163 (/IDA) P53163 (/IDA) P53163 (/IDA) P53163 (/IDA) P53163 (/IDA) P53163 (/IDA)
Structural constituent of ribosome GO:0003735
The action of a molecule that contributes to the structural integrity of the ribosome.
5 P52815 (/TAS) Q2XYH0 (/TAS) Q2XYH0 (/TAS) Q9VSR5 (/TAS) Q9VSR5 (/TAS)
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
4 Q2XYH0 (/IGI) Q2XYH0 (/IGI) Q9VSR5 (/IGI) Q9VSR5 (/IGI)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
1 P52815 (/TAS)
Structural constituent of ribosome GO:0003735
The action of a molecule that contributes to the structural integrity of the ribosome.
1 Q9USJ9 (/ISM)

There are 16 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Translation GO:0006412
The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.
183 P0A7K2 (/IMP) P0A7K2 (/IMP) P0A7K2 (/IMP) P0A7K2 (/IMP) P0A7K2 (/IMP) P0A7K2 (/IMP) P0A7K2 (/IMP) P0A7K2 (/IMP) P0A7K2 (/IMP) P0A7K2 (/IMP)
(173 more)
Translation GO:0006412
The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.
22 O96202 (/ISS) O96202 (/ISS) O96202 (/ISS) O96202 (/ISS) O96202 (/ISS) O96202 (/ISS) O96202 (/ISS) O96202 (/ISS) O96202 (/ISS) O96202 (/ISS)
(12 more)
Mitochondrial translation GO:0032543
The chemical reactions and pathways resulting in the formation of a protein in a mitochondrion. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the mitochondrion has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code.
7 P53163 (/IC) P53163 (/IC) P53163 (/IC) P53163 (/IC) P53163 (/IC) P53163 (/IC) P53163 (/IC)
Translation GO:0006412
The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.
4 P36210 (/TAS) P36210 (/TAS) P36211 (/TAS) P36212 (/TAS)
Mitochondrion organization GO:0007005
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components.
4 Q2XYH0 (/IMP) Q2XYH0 (/IMP) Q9VSR5 (/IMP) Q9VSR5 (/IMP)
Positive regulation of cell growth GO:0030307
Any process that activates or increases the frequency, rate, extent or direction of cell growth.
4 Q2XYH0 (/IMP) Q2XYH0 (/IMP) Q9VSR5 (/IMP) Q9VSR5 (/IMP)
Mitochondrial translation GO:0032543
The chemical reactions and pathways resulting in the formation of a protein in a mitochondrion. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the mitochondrion has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code.
4 Q2XYH0 (/TAS) Q2XYH0 (/TAS) Q9VSR5 (/TAS) Q9VSR5 (/TAS)
Mitochondrial transcription GO:0006390
The synthesis of RNA from a mitochondrial DNA template, usually by a specific mitochondrial RNA polymerase.
1 P52815 (/IDA)
Mitochondrial transcription GO:0006390
The synthesis of RNA from a mitochondrial DNA template, usually by a specific mitochondrial RNA polymerase.
1 Q9DB15 (/ISO)
Response to cytokinin GO:0009735
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokinin stimulus.
1 P36212 (/IDA)
Mitochondrial translation GO:0032543
The chemical reactions and pathways resulting in the formation of a protein in a mitochondrion. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the mitochondrion has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code.
1 Q9USJ9 (/ISM)
Defense response to bacterium GO:0042742
Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.
1 P36212 (/IEP)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
1 P52815 (/IDA)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
1 Q9DB15 (/ISO)
Mitochondrial translational elongation GO:0070125
The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in a mitochondrion.
1 P52815 (/TAS)
Mitochondrial translational termination GO:0070126
The process resulting in the release of a polypeptide chain from the ribosome in a mitochondrion, usually in response to a termination codon (note that mitochondria use variants of the universal genetic code that differ between different taxa).
1 P52815 (/TAS)

There are 32 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
185 O51351 (/IDA) O51351 (/IDA) P0A7K2 (/IDA) P0A7K2 (/IDA) P0A7K2 (/IDA) P0A7K2 (/IDA) P0A7K2 (/IDA) P0A7K2 (/IDA) P0A7K2 (/IDA) P0A7K2 (/IDA)
(175 more)
Large ribosomal subunit GO:0015934
The larger of the two subunits of a ribosome. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site).
183 P0A7K2 (/IDA) P0A7K2 (/IDA) P0A7K2 (/IDA) P0A7K2 (/IDA) P0A7K2 (/IDA) P0A7K2 (/IDA) P0A7K2 (/IDA) P0A7K2 (/IDA) P0A7K2 (/IDA) P0A7K2 (/IDA)
(173 more)
Cytosolic large ribosomal subunit GO:0022625
The large subunit of a ribosome located in the cytosol.
183 P0A7K2 (/IDA) P0A7K2 (/IDA) P0A7K2 (/IDA) P0A7K2 (/IDA) P0A7K2 (/IDA) P0A7K2 (/IDA) P0A7K2 (/IDA) P0A7K2 (/IDA) P0A7K2 (/IDA) P0A7K2 (/IDA)
(173 more)
Cytosolic large ribosomal subunit GO:0022625
The large subunit of a ribosome located in the cytosol.
18 O96202 (/ISS) O96202 (/ISS) O96202 (/ISS) O96202 (/ISS) O96202 (/ISS) O96202 (/ISS) O96202 (/ISS) O96202 (/ISS) O96202 (/ISS) O96202 (/ISS)
(8 more)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
13 P53163 (/HDA) P53163 (/HDA) P53163 (/HDA) P53163 (/HDA) P53163 (/HDA) P53163 (/HDA) P53163 (/HDA) Q2XYH0 (/HDA) Q2XYH0 (/HDA) Q9DB15 (/HDA)
(3 more)
Cell wall GO:0005618
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
12 P9WHE3 (/HDA) P9WHE3 (/HDA) P9WHE3 (/HDA) P9WHE3 (/HDA) P9WHE3 (/HDA) P9WHE3 (/HDA) P9WHE3 (/HDA) P9WHE3 (/HDA) P9WHE3 (/HDA) P9WHE3 (/HDA)
(2 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
12 P9WHE3 (/HDA) P9WHE3 (/HDA) P9WHE3 (/HDA) P9WHE3 (/HDA) P9WHE3 (/HDA) P9WHE3 (/HDA) P9WHE3 (/HDA) P9WHE3 (/HDA) P9WHE3 (/HDA) P9WHE3 (/HDA)
(2 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
12 P9WHE3 (/HDA) P9WHE3 (/HDA) P9WHE3 (/HDA) P9WHE3 (/HDA) P9WHE3 (/HDA) P9WHE3 (/HDA) P9WHE3 (/HDA) P9WHE3 (/HDA) P9WHE3 (/HDA) P9WHE3 (/HDA)
(2 more)
Mitochondrial large ribosomal subunit GO:0005762
The larger of the two subunits of a mitochondrial ribosome. Two sites on the ribosomal large subunit are involved in translation: the aminoacyl site (A site) and peptidyl site (P site).
11 P52815 (/IDA) P53163 (/IDA) P53163 (/IDA) P53163 (/IDA) P53163 (/IDA) P53163 (/IDA) P53163 (/IDA) P53163 (/IDA) Q57X71 (/IDA) Q57X71 (/IDA)
(1 more)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
10 O96202 (/ISS) O96202 (/ISS) O96202 (/ISS) O96202 (/ISS) O96202 (/ISS) O96202 (/ISS) O96202 (/ISS) O96202 (/ISS) O96202 (/ISS) O96202 (/ISS)
Apicoplast GO:0020011
The plastid organelle found in apicomplexans.
10 O96202 (/RCA) O96202 (/RCA) O96202 (/RCA) O96202 (/RCA) O96202 (/RCA) O96202 (/RCA) O96202 (/RCA) O96202 (/RCA) O96202 (/RCA) O96202 (/RCA)
Mitochondrial nucleoid GO:0042645
The region of a mitochondrion to which the DNA is confined.
8 G8BJN1 (/IDA) P53163 (/IDA) P53163 (/IDA) P53163 (/IDA) P53163 (/IDA) P53163 (/IDA) P53163 (/IDA) P53163 (/IDA)
Mitochondrial large ribosomal subunit GO:0005762
The larger of the two subunits of a mitochondrial ribosome. Two sites on the ribosomal large subunit are involved in translation: the aminoacyl site (A site) and peptidyl site (P site).
7 P52827 (/ISS) Q2XYH0 (/ISS) Q2XYH0 (/ISS) Q7YR75 (/ISS) Q9DB15 (/ISS) Q9VSR5 (/ISS) Q9VSR5 (/ISS)
Mitochondrial large ribosomal subunit GO:0005762
The larger of the two subunits of a mitochondrial ribosome. Two sites on the ribosomal large subunit are involved in translation: the aminoacyl site (A site) and peptidyl site (P site).
5 P52815 (/TAS) Q2XYH0 (/TAS) Q2XYH0 (/TAS) Q9VSR5 (/TAS) Q9VSR5 (/TAS)
Plastid large ribosomal subunit GO:0000311
The larger of the two subunits of a plastid ribosome. Two sites on the ribosomal large subunit are involved in translation: the aminoacyl site (A site) and peptidyl site (P site).
4 P36210 (/ISS) P36210 (/ISS) P36211 (/ISS) P36212 (/ISS)
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
3 P36210 (/IDA) P36210 (/IDA) P36212 (/IDA)
Chloroplast thylakoid membrane GO:0009535
The pigmented membrane of a chloroplast thylakoid. An example of this component is found in Arabidopsis thaliana.
3 P36210 (/IDA) P36210 (/IDA) P36212 (/IDA)
Chloroplast stroma GO:0009570
The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis.
3 P36210 (/IDA) P36210 (/IDA) P36212 (/IDA)
Thylakoid GO:0009579
A membranous cellular structure that bears the photosynthetic pigments in plants, algae, and cyanobacteria. In cyanobacteria thylakoids are of various shapes and are attached to, or continuous with, the plasma membrane. In eukaryotes they are flattened, membrane-bounded disk-like structures located in the chloroplasts; in the chloroplasts of higher plants the thylakoids form dense stacks called grana. Isolated thylakoid preparations can carry out photosynthetic electron transport and the associated phosphorylation.
3 P36210 (/IDA) P36210 (/IDA) P36212 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
2 O04527 (/IDA) P52815 (/IDA)
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
2 P52815 (/TAS) Q7YR75 (/TAS)
Mitochondrial small ribosomal subunit GO:0005763
The smaller of the two subunits of a mitochondrial ribosome.
2 Q9VSR5 (/ISS) Q9VSR5 (/ISS)
Plasmodesma GO:0009506
A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell.
2 P36210 (/IDA) P36210 (/IDA)
Chloroplast envelope GO:0009941
The double lipid bilayer enclosing the chloroplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space.
2 P36210 (/IDA) P36210 (/IDA)
Chloroplast nucleoid GO:0042644
The region of a chloroplast to which the DNA is confined.
2 P36210 (/IDA) P36210 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q584I9 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q9DB15 (/ISO)
Mitochondrial ribosome GO:0005761
A ribosome found in the mitochondrion of a eukaryotic cell; contains a characteristic set of proteins distinct from those of cytosolic ribosomes.
1 Q9DB15 (/ISS)
Mitochondrial large ribosomal subunit GO:0005762
The larger of the two subunits of a mitochondrial ribosome. Two sites on the ribosomal large subunit are involved in translation: the aminoacyl site (A site) and peptidyl site (P site).
1 Q9USJ9 (/ISM)
Mitochondrial large ribosomal subunit GO:0005762
The larger of the two subunits of a mitochondrial ribosome. Two sites on the ribosomal large subunit are involved in translation: the aminoacyl site (A site) and peptidyl site (P site).
1 Q9DB15 (/ISO)
Nuclear lumen GO:0031981
The volume enclosed by the nuclear inner membrane.
1 Q584I9 (/IDA)
Ciliary plasm GO:0097014
All of the contents of a cilium, excluding the plasma membrane surrounding the cilium.
1 Q584I9 (/IDA)
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