The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
2-methylcitrate dehydratase PrpD
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 4: 2-methylcitrate dehydratase 2

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
2-methylcitrate dehydratase activity GO:0047547
Catalysis of the reaction: (2S,3S)-2-methylcitrate = cis-2-methylaconitate + H(2)O.
8 L7N5Q7 (/ISS) L7N5Q7 (/ISS) L7N5Q7 (/ISS) L7N5Q7 (/ISS) O06582 (/ISS) O06582 (/ISS) O06582 (/ISS) O06582 (/ISS)
2-methylcitrate dehydratase activity GO:0047547
Catalysis of the reaction: (2S,3S)-2-methylcitrate = cis-2-methylaconitate + H(2)O.
4 H8F0D6 (/IDA) H8F0D6 (/IDA) Q8NSH9 (/IDA) Q8NSL3 (/IDA)
2 iron, 2 sulfur cluster binding GO:0051537
Interacting selectively and non-covalently with a 2 iron, 2 sulfur (2Fe-2S) cluster; this cluster consists of two iron atoms, with two inorganic sulfur atoms found between the irons and acting as bridging ligands.
4 L7N5Q7 (/ISS) L7N5Q7 (/ISS) L7N5Q7 (/ISS) L7N5Q7 (/ISS)
2-methylcitrate dehydratase activity GO:0047547
Catalysis of the reaction: (2S,3S)-2-methylcitrate = cis-2-methylaconitate + H(2)O.
2 H8F0D6 (/IMP) H8F0D6 (/IMP)

There are 5 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Response to acidic pH GO:0010447
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH < 7. pH is a measure of the acidity or basicity of an aqueous solution.
4 O06582 (/IEP) O06582 (/IEP) O06582 (/IEP) O06582 (/IEP)
Propionate catabolic process, 2-methylcitrate cycle GO:0019629
The chemical reactions and pathways resulting in the breakdown of propionate that occurs in the 2-methylcitrate cycle.
4 O06582 (/IMP) O06582 (/IMP) O06582 (/IMP) O06582 (/IMP)
Propionate metabolic process, methylcitrate cycle GO:0019679
The chemical reactions and pathways involving propionate that occur in the methylcitrate cycle.
4 L7N5Q7 (/ISS) L7N5Q7 (/ISS) L7N5Q7 (/ISS) L7N5Q7 (/ISS)
Propionate metabolic process, methylcitrate cycle GO:0019679
The chemical reactions and pathways involving propionate that occur in the methylcitrate cycle.
3 H8F0D6 (/IDA) H8F0D6 (/IDA) Q8NSL3 (/IDA)
Propionate metabolic process, methylcitrate cycle GO:0019679
The chemical reactions and pathways involving propionate that occur in the methylcitrate cycle.
2 H8F0D6 (/IMP) H8F0D6 (/IMP)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cell wall GO:0005618
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
4 O06582 (/HDA) O06582 (/HDA) O06582 (/HDA) O06582 (/HDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
4 O06582 (/HDA) O06582 (/HDA) O06582 (/HDA) O06582 (/HDA)
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