CATH Superfamily 3.30.1010.10
Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 4
The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 4
".
FunFam 112: Serine/threonine-protein kinase tel1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 3 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein kinase activity GO:0004672
Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
|
1 | O74630 (/IMP) |
|
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
|
1 | O74630 (/IDA) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | O74630 (/IPI) |
There are 6 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Telomere maintenance GO:0000723
Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins, the length of telomeric DNA and the replication and repair of the DNA. These processes includes those that shorten, lengthen, replicate and repair the telomeric DNA sequences.
|
1 | O74630 (/IGI) |
|
DNA damage induced protein phosphorylation GO:0006975
The widespread phosphorylation of various molecules, triggering many downstream processes, that occurs in response to the detection of DNA damage.
|
1 | O74630 (/IMP) |
|
Positive regulation of DNA repair GO:0045739
Any process that activates or increases the frequency, rate or extent of DNA repair.
|
1 | O74630 (/IMP) |
|
Positive regulation of mitotic DNA damage checkpoint GO:1904291
Any process that activates or increases the frequency, rate or extent of mitotic DNA damage checkpoint.
|
1 | O74630 (/IMP) |
|
Positive regulation of initiation of premeiotic DNA replication GO:1904514
Any process that activates or increases the frequency, rate or extent of initiation of premeiotic DNA replication.
|
1 | O74630 (/IMP) |
|
Histone H2A SQE motif phosphorylation GO:1990853
The modification of histone H2A by the addition of an phosphate group to the serine residue in the SQE motif of the histone.
|
1 | O74630 (/IMP) |
There are 1 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | O74630 (/HDA) |
