The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Regulatory factor, effector binding domain
".
FunFam 4: DNA gyrase inhibitor
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 2 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
DNA topoisomerase (ATP-hydrolyzing) inhibitor activity GO:0008657
Stops, prevents or reduces the activity of ATP-hydrolyzing DNA topoisomerase. ATP-hydrolyzing DNA topoisomerase catalyzes the DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2.
|
27 |
P33012 (/IDA)
P33012 (/IDA)
P33012 (/IDA)
P33012 (/IDA)
P33012 (/IDA)
P33012 (/IDA)
P33012 (/IDA)
P33012 (/IDA)
P33012 (/IDA)
P33012 (/IDA)
(17 more) |
|
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
|
27 |
P33012 (/IPI)
P33012 (/IPI)
P33012 (/IPI)
P33012 (/IPI)
P33012 (/IPI)
P33012 (/IPI)
P33012 (/IPI)
P33012 (/IPI)
P33012 (/IPI)
P33012 (/IPI)
(17 more) |
There are 2 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cellular response to DNA damage stimulus GO:0006974
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
|
27 |
P33012 (/IEP)
P33012 (/IEP)
P33012 (/IEP)
P33012 (/IEP)
P33012 (/IEP)
P33012 (/IEP)
P33012 (/IEP)
P33012 (/IEP)
P33012 (/IEP)
P33012 (/IEP)
(17 more) |
|
Negative regulation of DNA-dependent DNA replication GO:2000104
Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent DNA replication.
|
27 |
P33012 (/IDA)
P33012 (/IDA)
P33012 (/IDA)
P33012 (/IDA)
P33012 (/IDA)
P33012 (/IDA)
P33012 (/IDA)
P33012 (/IDA)
P33012 (/IDA)
P33012 (/IDA)
(17 more) |
There are 0 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
