The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Aldolase class I
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 70: Alpha-galactosidase

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Alpha-N-acetylgalactosaminidase. [EC: 3.2.1.49]
Cleavage of non-reducing alpha-(1->3)-N-acetylgalactosamine residues from human blood group A and AB mucin glycoproteins, Forssman hapten and blood group A lacto series glycolipids.
  • The human lysosomal enzyme is involved in the degradation of blood type A epitope.
8 A0A024R1Q5 A0A024R1Q5 P17050 P17050 Q58DH9 Q66H12 Q90744 Q9QWR8
Alpha-galactosidase. [EC: 3.2.1.22]
Hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha- D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids.
  • Also hydrolyzes alpha-D-fucosides.
5 P06280 P06280 P51569 Q53Y83 Q53Y83
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