The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Aldolase class I
".
FunFam 153: 4-hydroxy-2-oxoglutarate aldolase, mitochondrial i...
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 6 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
4-hydroxy-2-oxoglutarate aldolase activity GO:0008700
Catalysis of the reaction: 4-hydroxy-2-oxoglutarate = pyruvate + glyoxylate.
|
4 | Q6NY77 (/ISS) Q86XE5 (/ISS) Q86XE5 (/ISS) Q9DCU9 (/ISS) |
|
4-hydroxy-2-oxoglutarate aldolase activity GO:0008700
Catalysis of the reaction: 4-hydroxy-2-oxoglutarate = pyruvate + glyoxylate.
|
3 | Q0P5I5 (/IDA) Q86XE5 (/IDA) Q86XE5 (/IDA) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | Q86XE5 (/IPI) Q86XE5 (/IPI) |
|
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
2 | Q86XE5 (/IDA) Q86XE5 (/IDA) |
|
4-hydroxy-2-oxoglutarate aldolase activity GO:0008700
Catalysis of the reaction: 4-hydroxy-2-oxoglutarate = pyruvate + glyoxylate.
|
1 | Q9DCU9 (/ISO) |
|
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
1 | Q9DCU9 (/ISO) |
There are 13 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Glyoxylate catabolic process GO:0009436
The chemical reactions and pathways resulting in the breakdown of glyoxylate, the anion of glyoxylic acid, HOC-COOH.
|
2 | Q86XE5 (/IMP) Q86XE5 (/IMP) |
|
Glyoxylate catabolic process GO:0009436
The chemical reactions and pathways resulting in the breakdown of glyoxylate, the anion of glyoxylic acid, HOC-COOH.
|
2 | Q6NY77 (/ISS) Q9DCU9 (/ISS) |
|
4-hydroxyproline catabolic process GO:0019470
The chemical reactions and pathways resulting in the breakdown of 4-hydroxyproline, C5H9NO3, a derivative of the amino acid proline.
|
2 | Q86XE5 (/IDA) Q86XE5 (/IDA) |
|
Oxalate metabolic process GO:0033609
The chemical reactions and pathways involving oxalate, the organic acid ethanedioate.
|
2 | Q86XE5 (/IMP) Q86XE5 (/IMP) |
|
Pyruvate biosynthetic process GO:0042866
The chemical reactions and pathways resulting in the formation of pyruvate, 2-oxopropanoate.
|
2 | Q86XE5 (/IDA) Q86XE5 (/IDA) |
|
Glyoxylate metabolic process GO:0046487
The chemical reactions and pathways involving glyoxylate, the anion of glyoxylic acid, HOC-COOH.
|
2 | Q86XE5 (/IDA) Q86XE5 (/IDA) |
|
Glyoxylate metabolic process GO:0046487
The chemical reactions and pathways involving glyoxylate, the anion of glyoxylic acid, HOC-COOH.
|
2 | Q86XE5 (/TAS) Q86XE5 (/TAS) |
|
Glyoxylate catabolic process GO:0009436
The chemical reactions and pathways resulting in the breakdown of glyoxylate, the anion of glyoxylic acid, HOC-COOH.
|
1 | Q0P5I5 (/IDA) |
|
Glyoxylate catabolic process GO:0009436
The chemical reactions and pathways resulting in the breakdown of glyoxylate, the anion of glyoxylic acid, HOC-COOH.
|
1 | Q9DCU9 (/ISO) |
|
4-hydroxyproline catabolic process GO:0019470
The chemical reactions and pathways resulting in the breakdown of 4-hydroxyproline, C5H9NO3, a derivative of the amino acid proline.
|
1 | Q9DCU9 (/ISO) |
|
Oxalate metabolic process GO:0033609
The chemical reactions and pathways involving oxalate, the organic acid ethanedioate.
|
1 | Q9DCU9 (/ISO) |
|
Pyruvate biosynthetic process GO:0042866
The chemical reactions and pathways resulting in the formation of pyruvate, 2-oxopropanoate.
|
1 | Q9DCU9 (/ISO) |
|
Glyoxylate metabolic process GO:0046487
The chemical reactions and pathways involving glyoxylate, the anion of glyoxylic acid, HOC-COOH.
|
1 | Q9DCU9 (/ISO) |
There are 4 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
2 | Q86XE5 (/ISS) Q86XE5 (/ISS) |
|
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
|
2 | Q86XE5 (/TAS) Q86XE5 (/TAS) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
1 | Q9DCU9 (/HDA) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
1 | Q0P5I5 (/IDA) |
