The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Aldolase class I
".
FunFam 104: Thiamine biosynthetic bifunctional enzyme
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 7 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Hydroxyethylthiazole kinase activity GO:0004417
Catalysis of the reaction: 5-(2-hydroxyethyl)-4-methylthiazole + ATP = 4-methyl-5-(2-phosphoethyl)-thiazole + ADP + 2 H(+).
|
8 | P41835 (/IMP) P41835 (/IMP) P41835 (/IMP) P41835 (/IMP) P41835 (/IMP) P41835 (/IMP) P41835 (/IMP) P41835 (/IMP) |
|
Thiamine-phosphate diphosphorylase activity GO:0004789
Catalysis of the reaction: 4-amino-2-methyl-5-diphosphomethylpyrimidine + 4-methyl-5-(2-phosphoethyl)-thiazole + H(+) = diphosphate + thiamine phosphate.
|
8 | P41835 (/IMP) P41835 (/IMP) P41835 (/IMP) P41835 (/IMP) P41835 (/IMP) P41835 (/IMP) P41835 (/IMP) P41835 (/IMP) |
|
Thiamine-phosphate diphosphorylase activity GO:0004789
Catalysis of the reaction: 4-amino-2-methyl-5-diphosphomethylpyrimidine + 4-methyl-5-(2-phosphoethyl)-thiazole + H(+) = diphosphate + thiamine phosphate.
|
3 | Q5M731 (/IDA) Q5M731 (/IDA) Q6FV03 (/IDA) |
|
Thiamine-phosphate diphosphorylase activity GO:0004789
Catalysis of the reaction: 4-amino-2-methyl-5-diphosphomethylpyrimidine + 4-methyl-5-(2-phosphoethyl)-thiazole + H(+) = diphosphate + thiamine phosphate.
|
3 | O48881 (/IGI) Q5M731 (/IGI) Q5M731 (/IGI) |
|
Hydroxymethylpyrimidine kinase activity GO:0008902
Catalysis of the reaction: 4-amino-5-hydroxymethyl-2-methylpyrimidine + ATP = 4-amino-2-methyl-5-phosphomethylpyrimidine + ADP + 2 H(+).
|
3 | O48881 (/IGI) Q5M731 (/IGI) Q5M731 (/IGI) |
|
Phosphomethylpyrimidine kinase activity GO:0008972
Catalysis of the reaction: ATP + 4-amino-2-methyl-5-phosphomethylpyrimidine = ADP + 4-amino-2-methyl-5-diphosphomethylpyrimidine.
|
2 | Q5M731 (/IGI) Q5M731 (/IGI) |
|
Hydroxyethylthiazole kinase activity GO:0004417
Catalysis of the reaction: 5-(2-hydroxyethyl)-4-methylthiazole + ATP = 4-methyl-5-(2-phosphoethyl)-thiazole + ADP + 2 H(+).
|
1 | Q6FV03 (/IDA) |
There are 3 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Thiamine biosynthetic process GO:0009228
The chemical reactions and pathways resulting in the formation of thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver.
|
10 | P41835 (/IMP) P41835 (/IMP) P41835 (/IMP) P41835 (/IMP) P41835 (/IMP) P41835 (/IMP) P41835 (/IMP) P41835 (/IMP) Q5M731 (/IMP) Q5M731 (/IMP) |
|
Thiamine biosynthetic process GO:0009228
The chemical reactions and pathways resulting in the formation of thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver.
|
1 | O48881 (/IGI) |
|
Thiamine biosynthetic process GO:0009228
The chemical reactions and pathways resulting in the formation of thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver.
|
1 | Q6FV03 (/ISO) |
There are 5 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
9 | P40386 (/HDA) P41835 (/HDA) P41835 (/HDA) P41835 (/HDA) P41835 (/HDA) P41835 (/HDA) P41835 (/HDA) P41835 (/HDA) P41835 (/HDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
8 | P41835 (/IDA) P41835 (/IDA) P41835 (/IDA) P41835 (/IDA) P41835 (/IDA) P41835 (/IDA) P41835 (/IDA) P41835 (/IDA) |
|
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
|
2 | Q5M731 (/IDA) Q5M731 (/IDA) |
|
Chloroplast stroma GO:0009570
The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis.
|
2 | Q5M731 (/IDA) Q5M731 (/IDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | P40386 (/HDA) |
