The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Methylmalonyl-CoA mutase
".
FunFam 2: Methylmalonyl-CoA mutase, mitochondrial
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 18 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
|
5 | P16332 (/ISS) Q5RFN2 (/ISS) Q8HXX1 (/ISS) Q8MI68 (/ISS) Q9GK13 (/ISS) |
|
Cobalamin binding GO:0031419
Interacting selectively and non-covalently with cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom.
|
5 | P16332 (/ISS) Q5RFN2 (/ISS) Q8HXX1 (/ISS) Q8MI68 (/ISS) Q9GK13 (/ISS) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
5 | P16332 (/ISS) Q5RFN2 (/ISS) Q8HXX1 (/ISS) Q8MI68 (/ISS) Q9GK13 (/ISS) |
|
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
5 | P16332 (/ISS) Q5RFN2 (/ISS) Q8HXX1 (/ISS) Q8MI68 (/ISS) Q9GK13 (/ISS) |
|
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
|
2 | P22033 (/IDA) P22033 (/IDA) |
|
Methylmalonyl-CoA mutase activity GO:0004494
Catalysis of the reaction: (R)-methylmalonyl-CoA = succinyl-CoA.
|
2 | P22033 (/IMP) P22033 (/IMP) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | P22033 (/IPI) P22033 (/IPI) |
|
Cobalamin binding GO:0031419
Interacting selectively and non-covalently with cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom.
|
2 | P22033 (/IDA) P22033 (/IDA) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
2 | P22033 (/IDA) P22033 (/IDA) |
|
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
2 | P22033 (/IDA) P22033 (/IDA) |
|
Modified amino acid binding GO:0072341
Interacting selectively and non-covalently with a modified amino acid.
|
2 | P22033 (/IDA) P22033 (/IDA) |
|
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
|
1 | P16332 (/ISO) |
|
Methylmalonyl-CoA mutase activity GO:0004494
Catalysis of the reaction: (R)-methylmalonyl-CoA = succinyl-CoA.
|
1 | P16332 (/IDA) |
|
Methylmalonyl-CoA mutase activity GO:0004494
Catalysis of the reaction: (R)-methylmalonyl-CoA = succinyl-CoA.
|
1 | P16332 (/ISO) |
|
Cobalamin binding GO:0031419
Interacting selectively and non-covalently with cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom.
|
1 | P16332 (/ISO) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
1 | P16332 (/ISO) |
|
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
1 | P16332 (/ISO) |
|
Modified amino acid binding GO:0072341
Interacting selectively and non-covalently with a modified amino acid.
|
1 | P16332 (/ISO) |
There are 7 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cobalamin metabolic process GO:0009235
The chemical reactions and pathways involving cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom.
|
2 | P22033 (/TAS) P22033 (/TAS) |
|
Short-chain fatty acid catabolic process GO:0019626
The chemical reactions and pathways resulting in the breakdown of fatty acids with a chain length of less than C6.
|
2 | P22033 (/TAS) P22033 (/TAS) |
|
Positive regulation of GTPase activity GO:0043547
Any process that activates or increases the activity of a GTPase.
|
2 | P22033 (/IDA) P22033 (/IDA) |
|
Homocysteine metabolic process GO:0050667
The chemical reactions and pathways involving homocysteine, the amino acid alpha-amino-gamma-mercaptobutanoic acid. Homocysteine is an important intermediate in the metabolic reactions of its S-methyl derivative, methionine.
|
2 | P22033 (/IDA) P22033 (/IDA) |
|
Post-embryonic development GO:0009791
The process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. See embryonic development.
|
1 | P16332 (/IMP) |
|
Positive regulation of GTPase activity GO:0043547
Any process that activates or increases the activity of a GTPase.
|
1 | P16332 (/ISO) |
|
Homocysteine metabolic process GO:0050667
The chemical reactions and pathways involving homocysteine, the amino acid alpha-amino-gamma-mercaptobutanoic acid. Homocysteine is an important intermediate in the metabolic reactions of its S-methyl derivative, methionine.
|
1 | P16332 (/ISO) |
There are 3 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
2 | P16332 (/HDA) Q23381 (/HDA) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
2 | P22033 (/TAS) P22033 (/TAS) |
|
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
|
2 | P22033 (/TAS) P22033 (/TAS) |
