CATH Superfamily 3.20.20.220
The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 2: Methylenetetrahydrofolate reductase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 5 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Methylenetetrahydrofolate reductase (NAD(P)H) activity GO:0004489
Catalysis of the reaction: 5-methyltetrahydrofolate + NAD(P)+ = 5,10-methylenetetrahydrofolate + NAD(P)H + H+.
|
8 | O74927 (/IMP) Q10258 (/IMP) Q5AU15 (/IMP) Q5AU15 (/IMP) Q5AU15 (/IMP) Q5B0P7 (/IMP) Q5B0P7 (/IMP) Q5B0P7 (/IMP) |
|
Methylenetetrahydrofolate reductase (NAD(P)H) activity GO:0004489
Catalysis of the reaction: 5-methyltetrahydrofolate + NAD(P)+ = 5,10-methylenetetrahydrofolate + NAD(P)H + H+.
|
6 | P46151 (/IDA) P46151 (/IDA) P53128 (/IDA) P53128 (/IDA) P53128 (/IDA) P53128 (/IDA) |
|
Methylenetetrahydrofolate reductase (NAD(P)H) activity GO:0004489
Catalysis of the reaction: 5-methyltetrahydrofolate + NAD(P)+ = 5,10-methylenetetrahydrofolate + NAD(P)H + H+.
|
6 | Q5AU15 (/RCA) Q5AU15 (/RCA) Q5AU15 (/RCA) Q5B0P7 (/RCA) Q5B0P7 (/RCA) Q5B0P7 (/RCA) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
6 | P46151 (/IPI) P46151 (/IPI) P53128 (/IPI) P53128 (/IPI) P53128 (/IPI) P53128 (/IPI) |
|
Methylenetetrahydrofolate reductase (NAD(P)H) activity GO:0004489
Catalysis of the reaction: 5-methyltetrahydrofolate + NAD(P)+ = 5,10-methylenetetrahydrofolate + NAD(P)H + H+.
|
1 | Q54X84 (/ISS) |
There are 3 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Methionine biosynthetic process GO:0009086
The chemical reactions and pathways resulting in the formation of methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins.
|
12 |
O74927 (/IMP)
P53128 (/IMP)
P53128 (/IMP)
P53128 (/IMP)
P53128 (/IMP)
Q10258 (/IMP)
Q5AU15 (/IMP)
Q5AU15 (/IMP)
Q5AU15 (/IMP)
Q5B0P7 (/IMP)
(2 more) |
|
One-carbon metabolic process GO:0006730
The chemical reactions and pathways involving the transfer of one-carbon units in various oxidation states.
|
6 | Q5AU15 (/IMP) Q5AU15 (/IMP) Q5AU15 (/IMP) Q5B0P7 (/IMP) Q5B0P7 (/IMP) Q5B0P7 (/IMP) |
|
One-carbon metabolic process GO:0006730
The chemical reactions and pathways involving the transfer of one-carbon units in various oxidation states.
|
6 | Q5AU15 (/RCA) Q5AU15 (/RCA) Q5AU15 (/RCA) Q5B0P7 (/RCA) Q5B0P7 (/RCA) Q5B0P7 (/RCA) |
There are 3 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
4 | P53128 (/HDA) P53128 (/HDA) P53128 (/HDA) P53128 (/HDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | O74927 (/ISO) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
1 | Q10258 (/ISS) |
