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CATH Superfamily 3.20.20.140

Metal-dependent hydrolases

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Metal-dependent hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 100: 2-pyrone-4,6-dicarboxylate hydrolase

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
4-sulfomuconolactone hydrolase. [EC: 3.1.1.92]
4-sulfomuconolactone + H(2)O = maleylacetate + sulfite.
  • The enzyme was isolated from the bacteria Hydrogenophaga intermedia and Agrobacterium radiobacter S2.
  • It catalyzes a step in the degradation of 4-sulfocatechol.
 5 A0A1L1PS70 A0A1L1PS70 A6XIG6 A6XIG6 A6XIG7
2-pyrone-4,6-dicarboxylate lactonase. [EC: 3.1.1.57]
2-oxo-2H-pyran-4,6-dicarboxylate + H(2)O = (1E)-4-oxobut-1-ene-1,2,4- tricarboxylate.
  • The product is most likely the keto-form of 4-oxalmesaconate (shown).
  • It can be converted to the enol-form, 4-hydroxybuta-1,3-diene-1,2,4- trioate, either spontaneously or by EC 5.3.2.8.
 2 O87170 Q93PS7
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