The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Transcription elongation factor, GreA/GreB, C-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Transcription elongation factor GreA

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Bacterial-type RNA polymerase holo enzyme binding GO:0001108
Interacting selectively and non-covalently with the basal transcription machinery which is composed of a bacterial-type RNA polymerase core enzyme and a sigma factor, the minimal set of factors required for formation of the preinitiation complex (PIC) by a bacterial-type RNA polymerase.
172 P0A6W5 (/IDA) P0A6W5 (/IDA) P0A6W5 (/IDA) P0A6W5 (/IDA) P0A6W5 (/IDA) P0A6W5 (/IDA) P0A6W5 (/IDA) P0A6W5 (/IDA) P0A6W5 (/IDA) P0A6W5 (/IDA)
(162 more)

There are 7 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of DNA-templated transcription, elongation GO:0032784
Any process that modulates the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase.
209 P0A6W5 (/IDA) P0A6W5 (/IDA) P0A6W5 (/IDA) P0A6W5 (/IDA) P0A6W5 (/IDA) P0A6W5 (/IDA) P0A6W5 (/IDA) P0A6W5 (/IDA) P0A6W5 (/IDA) P0A6W5 (/IDA)
(199 more)
DNA-templated transcription, elongation GO:0006354
The extension of an RNA molecule after transcription initiation and promoter clearance at a DNA-dependent RNA polymerase promoter by the addition of ribonucleotides catalyzed by an RNA polymerase.
172 P0A6W5 (/IDA) P0A6W5 (/IDA) P0A6W5 (/IDA) P0A6W5 (/IDA) P0A6W5 (/IDA) P0A6W5 (/IDA) P0A6W5 (/IDA) P0A6W5 (/IDA) P0A6W5 (/IDA) P0A6W5 (/IDA)
(162 more)
DNA-templated transcription, elongation GO:0006354
The extension of an RNA molecule after transcription initiation and promoter clearance at a DNA-dependent RNA polymerase promoter by the addition of ribonucleotides catalyzed by an RNA polymerase.
49 Q60BR4 (/ISS) Q71ZH4 (/ISS) Q71ZH4 (/ISS) Q71ZH4 (/ISS) Q71ZH4 (/ISS) Q71ZH4 (/ISS) Q71ZH4 (/ISS) Q71ZH4 (/ISS) Q71ZH4 (/ISS) Q71ZH4 (/ISS)
(39 more)
DNA-templated transcription, initiation GO:0006352
Any process involved in the assembly of the RNA polymerase preinitiation complex (PIC) at the core promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. The initiation phase ends just before and does not include promoter clearance, or release, which is the transition between the initiation and elongation phases of transcription.
37 P30128 (/IDA) P30128 (/IDA) P30128 (/IDA) P30128 (/IDA) P30128 (/IDA) P30128 (/IDA) P30128 (/IDA) P30128 (/IDA) P30128 (/IDA) P30128 (/IDA)
(27 more)
Positive regulation of mRNA cleavage GO:0031439
Any process that activates or increases the frequency, rate or extent of mRNA cleavage.
37 P30128 (/IMP) P30128 (/IMP) P30128 (/IMP) P30128 (/IMP) P30128 (/IMP) P30128 (/IMP) P30128 (/IMP) P30128 (/IMP) P30128 (/IMP) P30128 (/IMP)
(27 more)
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
18 Q60BR4 (/ISS) Q71ZH4 (/ISS) Q71ZH4 (/ISS) Q71ZH4 (/ISS) Q71ZH4 (/ISS) Q71ZH4 (/ISS) Q71ZH4 (/ISS) Q71ZH4 (/ISS) Q71ZH4 (/ISS) Q71ZH4 (/ISS)
(8 more)
Transcription, DNA-templated GO:0006351
The cellular synthesis of RNA on a template of DNA.
1 Q8E8N1 (/ISS)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
172 P0A6W5 (/HDA) P0A6W5 (/HDA) P0A6W5 (/HDA) P0A6W5 (/HDA) P0A6W5 (/HDA) P0A6W5 (/HDA) P0A6W5 (/HDA) P0A6W5 (/HDA) P0A6W5 (/HDA) P0A6W5 (/HDA)
(162 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
172 P0A6W5 (/IDA) P0A6W5 (/IDA) P0A6W5 (/IDA) P0A6W5 (/IDA) P0A6W5 (/IDA) P0A6W5 (/IDA) P0A6W5 (/IDA) P0A6W5 (/IDA) P0A6W5 (/IDA) P0A6W5 (/IDA)
(162 more)
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