The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Antimicrobial Peptide, Beta-defensin 2; Chain A
".
FunFam 2: Beta-defensin 106A
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Lipopolysaccharide binding GO:0001530
Interacting selectively and non-covalently with lipopolysaccharide.
|
4 | Q8N104 (/IDA) Q8N104 (/IDA) Q8N104 (/IDA) Q8N104 (/IDA) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
4 | Q8N104 (/IPI) Q8N104 (/IPI) Q8N104 (/IPI) Q8N104 (/IPI) |
|
Heparin binding GO:0008201
Interacting selectively and non-covalently with heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells and which consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
|
4 | Q8N104 (/IDA) Q8N104 (/IDA) Q8N104 (/IDA) Q8N104 (/IDA) |
|
CCR2 chemokine receptor binding GO:0031727
Interacting selectively and non-covalently with a CCR2 chemokine receptor.
|
4 | Q8N104 (/IDA) Q8N104 (/IDA) Q8N104 (/IDA) Q8N104 (/IDA) |
There are 4 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Innate immune response GO:0045087
Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens.
|
4 | Q8N104 (/IDA) Q8N104 (/IDA) Q8N104 (/IDA) Q8N104 (/IDA) |
|
Defense response to Gram-negative bacterium GO:0050829
Reactions triggered in response to the presence of a Gram-negative bacterium that act to protect the cell or organism.
|
4 | Q8N104 (/IDA) Q8N104 (/IDA) Q8N104 (/IDA) Q8N104 (/IDA) |
|
Defense response to Gram-positive bacterium GO:0050830
Reactions triggered in response to the presence of a Gram-positive bacterium that act to protect the cell or organism.
|
4 | Q8N104 (/IDA) Q8N104 (/IDA) Q8N104 (/IDA) Q8N104 (/IDA) |
|
Antifungal innate immune response GO:0061760
An defense response against a fungus mediated through an innate immune response. An innate immune response is mediated by germline encoded components that directly recognize components of potential pathogens.
|
4 | Q8N104 (/IDA) Q8N104 (/IDA) Q8N104 (/IDA) Q8N104 (/IDA) |
There are 3 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
4 | Q8N104 (/IDA) Q8N104 (/IDA) Q8N104 (/IDA) Q8N104 (/IDA) |
|
Extrinsic component of membrane GO:0019898
The component of a membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
|
4 | Q8N104 (/IDA) Q8N104 (/IDA) Q8N104 (/IDA) Q8N104 (/IDA) |
|
Microvesicle GO:1990742
An extracellular vesicle released from the plasma membrane and ranging in size from about 100 nm to 1000 nm.
|
4 | Q8N104 (/IDA) Q8N104 (/IDA) Q8N104 (/IDA) Q8N104 (/IDA) |
