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CATH Superfamily 3.10.290.60

Ubiquitin-activating enzyme E1, UFD domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Ubiquitin-activating enzyme E1, UFD domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Ubiquitin-activating enzyme E1, UFD domain

The negatively charged C-terminal ubiquitin-fold domain (UFD) is primed for binding of E2s and recognises their positively charged first alpha-helix via electrostatic interactions.

GO Diversity

Unique GO annotations
53 Unique GO terms

EC Diversity

Unique EC annotations
1 Unique EC terms

Species Diversity

Unique species annotations
1420 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Structures
Domains: 20
Domain clusters (>95% seq id): 3
Domain clusters (>35% seq id): 1
Unique PDBs: 11
Alignments
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 10
Function
Unique EC: 1
Unique GO: 53
Taxonomy
Unique Species: 1420
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