Special AT-rich sequence-binding protein (SATB) is a global chromatin organizer and gene expression regulator essential for T-cell development and breast cancer tumor growth and metastasis. This entry represents the N-terminal oligomerisation domain, also known as ULD domain, of the SATB protein which enables tetramer formation, essential for the recognition of DNA sequences (such as multiple AT-rich DNA fragments). Thus, it is believed that SATBs regulate gene expression directly by binding to various promoters and upstream regions and thereby influencing promoter activity PMID:22241778,PMID:25124042.