The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Glutamine synthetase, N-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 1: Glutamine synthetase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Glutamate-ammonia ligase activity GO:0004356
Catalysis of the reaction: L-glutamate + ATP + NH(3) = L-glutamine + ADP + 2 H(+) + phosphate.
172 P0A9C5 (/IDA) P0A9C5 (/IDA) P0A9C5 (/IDA) P0A9C5 (/IDA) P0A9C5 (/IDA) P0A9C5 (/IDA) P0A9C5 (/IDA) P0A9C5 (/IDA) P0A9C5 (/IDA) P0A9C5 (/IDA)
(162 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
163 P0A9C5 (/IPI) P0A9C5 (/IPI) P0A9C5 (/IPI) P0A9C5 (/IPI) P0A9C5 (/IPI) P0A9C5 (/IPI) P0A9C5 (/IPI) P0A9C5 (/IPI) P0A9C5 (/IPI) P0A9C5 (/IPI)
(153 more)
Glutamate-ammonia ligase activity GO:0004356
Catalysis of the reaction: L-glutamate + ATP + NH(3) = L-glutamine + ADP + 2 H(+) + phosphate.
9 Q9KNJ2 (/ISS) Q9KNJ2 (/ISS) Q9KNJ2 (/ISS) Q9KNJ2 (/ISS) Q9KNJ2 (/ISS) Q9KNJ2 (/ISS) Q9KNJ2 (/ISS) Q9KNJ2 (/ISS) Q9KNJ2 (/ISS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 P77961 (/IPI)
3-(hydroxyamino)phenol mutase activity GO:0034022
Catalysis of the reaction: 3-hydroxyaminophenol = aminohydroquinone.
1 Q46ZL2 (/IDA)

There are 5 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Response to radiation GO:0009314
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation.
163 P0A9C5 (/IMP) P0A9C5 (/IMP) P0A9C5 (/IMP) P0A9C5 (/IMP) P0A9C5 (/IMP) P0A9C5 (/IMP) P0A9C5 (/IMP) P0A9C5 (/IMP) P0A9C5 (/IMP) P0A9C5 (/IMP)
(153 more)
Ammonia assimilation cycle GO:0019676
The pathway by which ammonia is processed and incorporated into a cell. In an energy-rich (glucose-containing), nitrogen-poor environment, glutamine synthetase and glutamate synthase form an ammonia assimilatory cycle, in which ammonia is incorporated into L-glutamate to form L-glutamine, which then combines with alpha-ketoglutarate to regenerate L-glutamate. This ATP-dependent cycle is essential for nitrogen-limited growth and for steady-state growth with some sources of nitrogen.
163 P0A9C5 (/IDA) P0A9C5 (/IDA) P0A9C5 (/IDA) P0A9C5 (/IDA) P0A9C5 (/IDA) P0A9C5 (/IDA) P0A9C5 (/IDA) P0A9C5 (/IDA) P0A9C5 (/IDA) P0A9C5 (/IDA)
(153 more)
Nitrogen utilization GO:0019740
A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary nitrogen source, usually ammonia, and then activates genes to scavenge the last traces of the primary nitrogen source and to transport and metabolize alternative nitrogen sources. The utilization process begins when the cell or organism detects nitrogen levels, includes the activation of genes whose products detect, transport or metabolize nitrogen-containing substances, and ends when nitrogen is incorporated into the cell or organism's metabolism.
163 P0A9C5 (/IDA) P0A9C5 (/IDA) P0A9C5 (/IDA) P0A9C5 (/IDA) P0A9C5 (/IDA) P0A9C5 (/IDA) P0A9C5 (/IDA) P0A9C5 (/IDA) P0A9C5 (/IDA) P0A9C5 (/IDA)
(153 more)
Glutamine biosynthetic process GO:0006542
The chemical reactions and pathways resulting in the formation of glutamine, 2-amino-4-carbamoylbutanoic acid.
9 Q9KNJ2 (/ISS) Q9KNJ2 (/ISS) Q9KNJ2 (/ISS) Q9KNJ2 (/ISS) Q9KNJ2 (/ISS) Q9KNJ2 (/ISS) Q9KNJ2 (/ISS) Q9KNJ2 (/ISS) Q9KNJ2 (/ISS)
Benzene-containing compound metabolic process GO:0042537
The chemical reactions and pathways involving benzene, C6H6, a volatile, very inflammable liquid, contained in the naphtha produced by the destructive distillation of coal, from which it is separated by fractional distillation, or any of its derivatives.
1 Q46ZL2 (/IDA)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
163 P0A9C5 (/HDA) P0A9C5 (/HDA) P0A9C5 (/HDA) P0A9C5 (/HDA) P0A9C5 (/HDA) P0A9C5 (/HDA) P0A9C5 (/HDA) P0A9C5 (/HDA) P0A9C5 (/HDA) P0A9C5 (/HDA)
(153 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
163 P0A9C5 (/IDA) P0A9C5 (/IDA) P0A9C5 (/IDA) P0A9C5 (/IDA) P0A9C5 (/IDA) P0A9C5 (/IDA) P0A9C5 (/IDA) P0A9C5 (/IDA) P0A9C5 (/IDA) P0A9C5 (/IDA)
(153 more)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
163 P0A9C5 (/HDA) P0A9C5 (/HDA) P0A9C5 (/HDA) P0A9C5 (/HDA) P0A9C5 (/HDA) P0A9C5 (/HDA) P0A9C5 (/HDA) P0A9C5 (/HDA) P0A9C5 (/HDA) P0A9C5 (/HDA)
(153 more)
CATH-Gene3D is a Global Biodata Core Resource Learn more...