The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1
".
FunFam 2: Lactoylglutathione lyase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Lactoylglutathione lyase activity GO:0004462
Catalysis of the reaction: (R)-S-lactoylglutathione = glutathione + methylglyoxal.
|
143 |
P0AC81 (/IDA)
P0AC81 (/IDA)
P0AC81 (/IDA)
P0AC81 (/IDA)
P0AC81 (/IDA)
P0AC81 (/IDA)
P0AC81 (/IDA)
P0AC81 (/IDA)
P0AC81 (/IDA)
P0AC81 (/IDA)
(133 more) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
143 |
P0AC81 (/IPI)
P0AC81 (/IPI)
P0AC81 (/IPI)
P0AC81 (/IPI)
P0AC81 (/IPI)
P0AC81 (/IPI)
P0AC81 (/IPI)
P0AC81 (/IPI)
P0AC81 (/IPI)
P0AC81 (/IPI)
(133 more) |
|
Nickel cation binding GO:0016151
Interacting selectively and non-covalently with nickel (Ni) cations.
|
143 |
P0AC81 (/IDA)
P0AC81 (/IDA)
P0AC81 (/IDA)
P0AC81 (/IDA)
P0AC81 (/IDA)
P0AC81 (/IDA)
P0AC81 (/IDA)
P0AC81 (/IDA)
P0AC81 (/IDA)
P0AC81 (/IDA)
(133 more) |
|
Lactoylglutathione lyase activity GO:0004462
Catalysis of the reaction: (R)-S-lactoylglutathione = glutathione + methylglyoxal.
|
7 | Q54EY7 (/ISS) Q9KT93 (/ISS) Q9KT93 (/ISS) Q9KT93 (/ISS) Q9KT93 (/ISS) Q9KT93 (/ISS) Q9KT93 (/ISS) |
There are 2 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione GO:0019243
The chemical reactions and pathways resulting in the breakdown of methylglyoxal, CH3-CO-CHO, into D-lactate via the intermediate S-lactoyl-glutathione. Glutathione is used in the first step of the pathway and then regenerated in the second step.
|
143 |
P0AC81 (/IMP)
P0AC81 (/IMP)
P0AC81 (/IMP)
P0AC81 (/IMP)
P0AC81 (/IMP)
P0AC81 (/IMP)
P0AC81 (/IMP)
P0AC81 (/IMP)
P0AC81 (/IMP)
P0AC81 (/IMP)
(133 more) |
|
Glutathione metabolic process GO:0006749
The chemical reactions and pathways involving glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins; it has a specific role in the reduction of hydrogen peroxide (H2O2) and oxidized ascorbate, and it participates in the gamma-glutamyl cycle.
|
7 | Q54EY7 (/ISS) Q9KT93 (/ISS) Q9KT93 (/ISS) Q9KT93 (/ISS) Q9KT93 (/ISS) Q9KT93 (/ISS) Q9KT93 (/ISS) |
There are 1 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
143 |
P0AC81 (/IDA)
P0AC81 (/IDA)
P0AC81 (/IDA)
P0AC81 (/IDA)
P0AC81 (/IDA)
P0AC81 (/IDA)
P0AC81 (/IDA)
P0AC81 (/IDA)
P0AC81 (/IDA)
P0AC81 (/IDA)
(133 more) |
