The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 12: 2,3-dihydroxybiphenyl 1,2-dioxygenase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Iron ion binding GO:0005506
Interacting selectively and non-covalently with iron (Fe) ions.
9 P9WNW7 (/IDA) P9WNW7 (/IDA) P9WNW7 (/IDA) P9WNW7 (/IDA) P9WNW7 (/IDA) P9WNW7 (/IDA) P9WNW7 (/IDA) P9WNW7 (/IDA) P9WNW7 (/IDA)
3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione 4,5-dioxygenase activity GO:0047071
Catalysis of the reaction: 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + O(2) = 3-hydroxy-5,9,17-trioxo-4,5:9,10-disecoandrosta-1(10),2-dien-4-oate + H(+).
9 P9WNW7 (/IDA) P9WNW7 (/IDA) P9WNW7 (/IDA) P9WNW7 (/IDA) P9WNW7 (/IDA) P9WNW7 (/IDA) P9WNW7 (/IDA) P9WNW7 (/IDA) P9WNW7 (/IDA)
Oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen GO:0016702
Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from one donor, and two oxygen atoms is incorporated into a donor.
1 Q9KWQ5 (/IDA)

There are 3 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Response to cholesterol GO:0070723
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholesterol stimulus.
10 P9WNW7 (/IEP) P9WNW7 (/IEP) P9WNW7 (/IEP) P9WNW7 (/IEP) P9WNW7 (/IEP) P9WNW7 (/IEP) P9WNW7 (/IEP) P9WNW7 (/IEP) P9WNW7 (/IEP) Q9KWQ5 (/IEP)
Cholesterol catabolic process GO:0006707
The chemical reactions and pathways resulting in the breakdown of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
9 P9WNW7 (/IDA) P9WNW7 (/IDA) P9WNW7 (/IDA) P9WNW7 (/IDA) P9WNW7 (/IDA) P9WNW7 (/IDA) P9WNW7 (/IDA) P9WNW7 (/IDA) P9WNW7 (/IDA)
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
9 P9WNW7 (/IDA) P9WNW7 (/IDA) P9WNW7 (/IDA) P9WNW7 (/IDA) P9WNW7 (/IDA) P9WNW7 (/IDA) P9WNW7 (/IDA) P9WNW7 (/IDA) P9WNW7 (/IDA)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
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