The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Polyketide synthase dehydratase
".
FunFam 8: Phenolpthiocerol synthesis type-I polyketide synth...
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Acyl carrier activity GO:0000036
Binding an acyl group and presenting it for processing or offloading to a cognate enzyme. Covalently binds the acyl group via a phosphopantetheine prosthetic group and mediates protein-protein interactions with the enzyme conferring specificity. The acyl carrier protein (ACP) presents substrates to enzymes involved in fatty acid biosynthesis or in polyketide secondary metabolite biosynthesis.
|
2 | P9WQE7 (/IDA) P9WQE7 (/IDA) |
|
3-oxoacyl-[acyl-carrier-protein] synthase activity GO:0004315
Catalysis of the reaction: acyl-
|
2 | P9WQE7 (/IDA) P9WQE7 (/IDA) |
|
3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity GO:0004316
Catalysis of the reaction: (3R)-3-hydroxyacyl-
|
2 | P9WQE7 (/IDA) P9WQE7 (/IDA) |
|
Phosphopantetheine binding GO:0031177
Interacting selectively and non-covalently with phosphopantetheine, the vitamin pantetheine 4'-(dihydrogen phosphate).
|
2 | P9WQE7 (/IDA) P9WQE7 (/IDA) |
There are 9 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Phthiocerol biosynthetic process GO:0097040
The chemical reactions and pathways resulting in the formation of phthiocerol, a lipid-based 1,3-glycol consisting of (3S,4R)-3-methoxy-4-methylnonacosane having (9R)- and (11S)-hydroxy substituents.
|
3 | P9WQE6 (/ISS) P9WQE7 (/ISS) P9WQE7 (/ISS) |
|
Phenolic phthiocerol biosynthetic process GO:0097041
The chemical reactions and pathways resulting in the formation of phenolic phthiocerol, a phthiocerol derivative having a 4-hydroxyphenyl substituent at the 29-position.
|
3 | P9WQE6 (/ISS) P9WQE7 (/ISS) P9WQE7 (/ISS) |
|
Fatty acid biosynthetic process GO:0006633
The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.
|
2 | P9WQE7 (/IDA) P9WQE7 (/IDA) |
|
Oxidation-reduction process GO:0055114
A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
|
2 | P9WQE7 (/IDA) P9WQE7 (/IDA) |
|
Actinobacterium-type cell wall biogenesis GO:0071766
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cell wall of the type found in Actinobacteria. The cell wall is the rigid or semi-rigid envelope lying outside the cell membrane. Actinobacterial cell walls contain characteristic mycolic acids, of which some are covalently linked to the cell wall peptidoglycan and others accumulate at the cell surface.
|
2 | Q7TXM0 (/IMP) Q7TXM0 (/IMP) |
|
DIM/DIP cell wall layer assembly GO:0071770
The aggregation, arrangement and bonding together of a set of components, including (phenyl)phthiocerol, phthiodiolone, phthiotriol dimycocerosate and diphthioceranate, to form the DIM/DIP layer of the Actinobacterium-type cell wall.
|
2 | P9WQE7 (/IDA) P9WQE7 (/IDA) |
|
Phthiocerol biosynthetic process GO:0097040
The chemical reactions and pathways resulting in the formation of phthiocerol, a lipid-based 1,3-glycol consisting of (3S,4R)-3-methoxy-4-methylnonacosane having (9R)- and (11S)-hydroxy substituents.
|
2 | Q7TXM0 (/IMP) Q7TXM0 (/IMP) |
|
Phenolic phthiocerol biosynthetic process GO:0097041
The chemical reactions and pathways resulting in the formation of phenolic phthiocerol, a phthiocerol derivative having a 4-hydroxyphenyl substituent at the 29-position.
|
2 | Q7TXM0 (/IMP) Q7TXM0 (/IMP) |
|
Actinobacterium-type cell wall biogenesis GO:0071766
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cell wall of the type found in Actinobacteria. The cell wall is the rigid or semi-rigid envelope lying outside the cell membrane. Actinobacterial cell walls contain characteristic mycolic acids, of which some are covalently linked to the cell wall peptidoglycan and others accumulate at the cell surface.
|
1 | P9WQE6 (/ISS) |
There are 3 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Polyketide synthase complex GO:0034081
A protein complex that carries out enzymatic reactions involved in the biosynthesis of polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones.
|
3 | P9WQE6 (/ISS) P9WQE7 (/ISS) P9WQE7 (/ISS) |
|
Cell wall GO:0005618
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
|
2 | P9WQE7 (/HDA) P9WQE7 (/HDA) |
|
Polyketide synthase complex GO:0034081
A protein complex that carries out enzymatic reactions involved in the biosynthesis of polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones.
|
2 | Q7TXM0 (/IMP) Q7TXM0 (/IMP) |
