The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Hotdog Thioesterase
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 20: Acyl-coenzyme A thioesterase 11

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 7 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Acyl-CoA hydrolase activity GO:0047617
Catalysis of the reaction: acyl-CoA + H2O = CoA + a carboxylate.
3 Q8VHQ9 (/TAS) Q8VHQ9 (/TAS) Q8WXI4 (/TAS)
Palmitoyl-CoA hydrolase activity GO:0016290
Catalysis of the reaction: palmitoyl-CoA + H2O = CoA + palmitate.
2 Q8VHQ9 (/ISO) Q8VHQ9 (/ISO)
Palmitoyl-CoA hydrolase activity GO:0016290
Catalysis of the reaction: palmitoyl-CoA + H2O = CoA + palmitate.
2 Q8VHQ9 (/ISS) Q8VHQ9 (/ISS)
Acyl-CoA hydrolase activity GO:0047617
Catalysis of the reaction: acyl-CoA + H2O = CoA + a carboxylate.
2 Q8VHQ9 (/ISO) Q8VHQ9 (/ISO)
Acyl-CoA hydrolase activity GO:0047617
Catalysis of the reaction: acyl-CoA + H2O = CoA + a carboxylate.
2 Q8VHQ9 (/ISS) Q8VHQ9 (/ISS)
Long-chain acyl-CoA hydrolase activity GO:0052816
Catalysis of the reaction: H2O + a long-chain acyl-CoA = a long-chain carboxylate + CoA. A long chain is a chain of greater than 12 carbons in length.
2 Q8VHQ9 (/ISO) Q8VHQ9 (/ISO)
Long-chain acyl-CoA hydrolase activity GO:0052816
Catalysis of the reaction: H2O + a long-chain acyl-CoA = a long-chain carboxylate + CoA. A long chain is a chain of greater than 12 carbons in length.
2 Q8VHQ9 (/ISS) Q8VHQ9 (/ISS)

There are 9 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Fatty acid metabolic process GO:0006631
The chemical reactions and pathways involving fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.
3 Q8VHQ9 (/NAS) Q8VHQ9 (/NAS) Q8WXI4 (/NAS)
Intracellular signal transduction GO:0035556
The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.
3 Q8VHQ9 (/NAS) Q8VHQ9 (/NAS) Q8WXI4 (/NAS)
Response to temperature stimulus GO:0009266
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus.
2 Q8VHQ9 (/IEP) Q8VHQ9 (/IEP)
Response to cold GO:0009409
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.
2 Q8VHQ9 (/IEP) Q8VHQ9 (/IEP)
Negative regulation of cold-induced thermogenesis GO:0120163
Any process that stops, prevents, or reduces the rate of cold-induced thermogenesis.
2 Q8VHQ9 (/IMP) Q8VHQ9 (/IMP)
Negative regulation of cold-induced thermogenesis GO:0120163
Any process that stops, prevents, or reduces the rate of cold-induced thermogenesis.
2 F1LX28 (/ISS) Q8WXI4 (/ISS)
Acyl-CoA metabolic process GO:0006637
The chemical reactions and pathways involving acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with an acyl group.
1 Q8WXI4 (/TAS)
Response to temperature stimulus GO:0009266
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus.
1 Q8WXI4 (/ISS)
Response to cold GO:0009409
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.
1 Q8WXI4 (/ISS)

There are 8 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 Q8VHQ9 (/ISO) Q8VHQ9 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 Q8VHQ9 (/ISS) Q8VHQ9 (/ISS)
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
2 Q8VHQ9 (/ISO) Q8VHQ9 (/ISO)
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
2 Q8VHQ9 (/ISS) Q8VHQ9 (/ISS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 Q8VHQ9 (/ISO) Q8VHQ9 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q8WXI4 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q8WXI4 (/TAS)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
1 Q8WXI4 (/HDA)
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