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CATH Superfamily 2.70.170.10

Neurotransmitter-gated ion-channel ligand-binding domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Neurotransmitter-gated ion-channel ligand-binding domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
SC:1Gamma-aminobutyric acid A receptor subunit alpha-2Glycine receptor alpha 1 subunitPutative gamma-aminobutyric acid receptor subunit gamma-2Neuronal nicotinic acetylcholine receptor alpha4 subunitneuronal acetylcholine receptor subunit alpha-9Nicotinic acetylcholine receptor subunit gamma5-hydroxytryptamine receptor 3APutative acetylcholine receptor subunit alphaGlutamate-gated chloride channel alphaProton-gated ion channelGamma-aminobutyric-acid receptor subunit beta-1AchbpGamma-aminobutyric acid receptor subunit beta-2 isoform ACholinergic receptor nicotinic beta 2 subunitGamma-aminobutyric acid type A receptor rho2 subunitCholinergic receptor nicotinic alpha 6 subunitNeuronal acetylcholine receptor subunit alpha-7Gamma-aminobutyric acid receptor subunit pi isoform X1Acetylcholine receptor subunit alphaGlycine receptor subunit betagamma-aminobutyric acid receptor subunit rho-1 isoform X1Nicotinic acetylcholine receptor subunitGamma-aminobutyric acid (GABA-A) receptor, subunit deltaglutamate-gated chloride channel isoform X12Gamma-aminobutyric acid receptor isoform 3bglutamate-gated chloride channel isoform X1Acetylcholine receptor subunit beta-like 1Histamine-gated chloride channel subunitGamma-aminobutyric acid type A receptor beta3 subunit5-hydroxytryptamine receptor 3CLigand-Gated ion ChannelAcetylCholine ReceptorCholinergic receptor nicotinic alpha 10 subunitAcetylCholine ReceptorAcetylCholine ReceptorUncharacterized protein, isoform BGamma-aminobutyric acid (GABA-A) receptor, subunit thetaLigand-Gated ion ChannelLigand-Gated ion ChannelGamma-aminobutyric acid receptor subunit beta-likezinc-activated ligand-gated ion channelLigand-Gated ion ChannelCholinergic receptor nicotinic gamma subunitAcetylcholine receptor subunit gammaBlast:Glycine receptor subunit alpha-3Gamma-aminobutyric acid receptor alpha-likeAcetylCholine ReceptorPredicted proteinCholinergic receptor nicotinic alpha 1 subunitneuronal acetylcholine receptor subunit alpha-5 isoform X2Cholinergic receptor nicotinic alpha 1 subunitLigand-Gated ion ChannelNicotinic acetylcholine receptor alpha4, isoform DLigand-Gated ion ChannelLigand-Gated ion ChannelPredicted proteinLigand-Gated ion ChannelProton-gated ion channel subunit pbo-6Ligand-Gated ion ChannelLigand-Gated ion ChannelLigand-gated chloride channelUncharacterized protein, isoform FNicotinic acetylcholine receptor subunit alpha4Ligand-gated ion channel 4Histamine-gated chloride channel subunitLigand-Gated ion ChannelUncharacterized proteinGlutamate-gated chloride channel, putativeGlutamate-gated ChLoride channelLigand-Gated ion ChannelLOW QUALITY PROTEIN: 5-hydroxytryptamine receptor 3C-likeAcetylcholine-gated chloride channel subunit acc-1Ligand-Gated ion ChannelNicotinic acetylcholine receptor Dalpha7 subunitUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinGamma-aminobutyric acid receptor subunit gamma-3Acetylcholine-gated chloride channel subunit acc-3Gamma-aminobutyric acid receptor subunit alpha-4Uncharacterized proteinAcetylcholine receptor subunit alpha-type unc-63Ligand-Gated ion ChannelUncharacterized proteinAcetylCholine ReceptorLigand-Gated ion ChannelProbable ligand-gated ion channel 46NtR, isoform AGamma-aminobutyric acid type A receptor alpha6 subunitLigand-Gated ion ChannelUncharacterized proteingamma-aminobutyric acid receptor subunit rho-1-like isoform X2Gamma-aminobutyric acid type A receptor alpha2 subunitGamma-aminobutyric acid type A receptor alpha6 subunitcDNA FLJ56966, highly similar to Gamma-aminobutyric-acid receptor alpha-5 subunitUncharacterized proteinGamma-aminobutyric acid receptor subunit betaUncharacterized protein, isoform DNeuronal acetylcholine receptor subunit alpha-9Gamma-aminobutyric acid type A receptor rho1 subunitProtein CBR-LGC-28Uncharacterized proteinPredicted proteinPredicted proteinUncharacterized proteinNicotinic acetylcholine receptor a9 subunit splice variantSi:ch211-39a7.1Uncharacterized proteinLigand-Gated ion ChannelUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinGamma-aminobutyric acid type A receptor pi subunitLigand-Gated ion ChannelSi:ch73-380n15.2CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusionGH14445pAGAP010057-PAAcetylcholine receptor subunit alphaCholinergic receptor nicotinic epsilon subunitPredicted proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinPredicted proteinUncharacterized proteinUncharacterized proteinPredicted proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinPredicted proteinGlutamate-gated chloride channel, putativeUncharacterized proteinUncharacterized proteinUncharacterized proteinTransmembrane ion channelNicotinic acetylcholine receptor a10 subunit splice variantLigand-Gated ion Channelgamma-aminobutyric acid receptor subunit beta-3-likeTransmembrane ion channelTransmembrane ion channelProtein CBR-LGC-31Uncharacterized protein5-hydroxytryptamine receptor 3DLigand-Gated ion ChannelNicotinic acetylcholine receptor subunitCHRNA7-FAM7A fusion proteinUncharacterized proteinMacaca fascicularis brain cDNA clone: QflA-17345, similar to human cholinergic receptor, nicotinic, beta polypeptide 2(neuronal) (CHRNB2), mRNA, RefSeq: NM_000748.1Uncharacterized proteinUncharacterized proteinNicotinic acetylcyoline receptor Dalpha 4 subunitUncharacterized proteinCHRNA7-FAM7A fusion proteinPredicted proteinTransmembrane ion channelTransmembrane ion channelNeurotransmitter gated ion channel, putativeUncharacterized proteinNeurotransmitter gated ion channel, putativeProtein CBR-ACR-8Protein CBR-DEG-3Uncharacterized proteinProtein CBR-ACR-8Nicotinic acetylcholine receptor alpha 9 subunitUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinSi:ch211-256e16.10Uncharacterized proteinProtein CBR-DEG-3Glycine receptor alpha 2Uncharacterized proteinProtein CBG10414Neuronal acetylcholine receptor subunit alpha-3, putativeUncharacterized proteinPredicted proteinUncharacterized proteinUncharacterized proteinPredicted proteinPredicted proteinAGAP009493-PAUncharacterized proteinUncharacterized proteinUncharacterized proteinPredicted proteinUncharacterized proteinPredicted proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinGamma-aminobutyric acid type A receptor alpha2 subunit aUncharacterized proteinPredicted proteinUncharacterized proteinPredicted proteinGaba-gated chloride channel, putativeUncharacterized proteinUncharacterized proteinUncharacterized proteinGlutamate-gated chloride channel, putativeUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinProtein CBR-PBO-6Uncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinProtein CBR-EXP-1Predicted proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinGlycine receptor alpha 1 variant, putativeUncharacterized proteinPredicted proteinUncharacterized proteinUncharacterized proteinCholinergic receptor, nicotinic alpha 9Uncharacterized proteinUncharacterized proteinCholinergic receptor, nicotinic, beta 2Uncharacterized proteinCholinergic receptor nicotinic beta 1 subunitUncharacterized proteinCholinergic receptor nicotinic alpha 10 subunitNicotinic acetylcholine receptor subunitSoluble acetylcholine receptorUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinProtein CBG01602Uncharacterized proteinUncharacterized proteinProtein CBG24733Uncharacterized proteinPredicted proteinAcetylcholine receptor subunit deltaGABA receptor alpha 6 subunitUncharacterized proteinPredicted proteinGamma-aminobutyric acid (GABA) A receptor, rho 1Uncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinPredicted proteinSD10415pPredicted proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinProtein CBG01074Predicted proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinSi:ch211-39a7.1Uncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinCholinergic receptor, nicotinic, alpha 6Uncharacterized proteinProtein CBG26995Uncharacterized proteinUncharacterized proteinCholinergic receptor nicotinic alpha 10 subunitUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinProtein CBG01074Protein CBG26995Uncharacterized proteinUncharacterized proteinUncharacterized protein
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FunFam 69: Acetylcholine-gated chloride channel subunit acc-1

GO Diversity

Unique GO annotations
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0 Unique GO terms

EC Diversity

Unique EC annotations
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0 Unique EC terms

Species Diversity

Unique species annotations
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6 Unique species

Statistics

Members
CATH Domains: 0
Sequences: 8
Annotations
Unique GO:
Unique EC: 0
Unique Species: 6
Representative
Rep ID: Q21005/23-235
Inherited Annotations: 0
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