The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Neurotransmitter-gated ion-channel ligand-binding domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
SC:1Gamma-aminobutyric acid A receptor subunit alpha-2Glycine receptor alpha 1 subunitPutative gamma-aminobutyric acid receptor subunit gamma-2Neuronal nicotinic acetylcholine receptor alpha4 subunitneuronal acetylcholine receptor subunit alpha-9Nicotinic acetylcholine receptor subunit gamma5-hydroxytryptamine receptor 3APutative acetylcholine receptor subunit alphaGlutamate-gated chloride channel alphaProton-gated ion channelGamma-aminobutyric-acid receptor subunit beta-1AchbpGamma-aminobutyric acid receptor subunit beta-2 isoform ACholinergic receptor nicotinic beta 2 subunitGamma-aminobutyric acid type A receptor rho2 subunitCholinergic receptor nicotinic alpha 6 subunitNeuronal acetylcholine receptor subunit alpha-7Gamma-aminobutyric acid receptor subunit pi isoform X1Acetylcholine receptor subunit alphaGlycine receptor subunit betagamma-aminobutyric acid receptor subunit rho-1 isoform X1Nicotinic acetylcholine receptor subunitGamma-aminobutyric acid (GABA-A) receptor, subunit deltaglutamate-gated chloride channel isoform X12Gamma-aminobutyric acid receptor isoform 3bglutamate-gated chloride channel isoform X1Acetylcholine receptor subunit beta-like 1Histamine-gated chloride channel subunitGamma-aminobutyric acid type A receptor beta3 subunit5-hydroxytryptamine receptor 3CLigand-Gated ion ChannelAcetylCholine ReceptorCholinergic receptor nicotinic alpha 10 subunitAcetylCholine ReceptorAcetylCholine ReceptorUncharacterized protein, isoform BGamma-aminobutyric acid (GABA-A) receptor, subunit thetaLigand-Gated ion ChannelLigand-Gated ion ChannelGamma-aminobutyric acid receptor subunit beta-likezinc-activated ligand-gated ion channelLigand-Gated ion ChannelCholinergic receptor nicotinic gamma subunitAcetylcholine receptor subunit gammaBlast:Glycine receptor subunit alpha-3Gamma-aminobutyric acid receptor alpha-likeAcetylCholine ReceptorPredicted proteinCholinergic receptor nicotinic alpha 1 subunitneuronal acetylcholine receptor subunit alpha-5 isoform X2Cholinergic receptor nicotinic alpha 1 subunitLigand-Gated ion ChannelNicotinic acetylcholine receptor alpha4, isoform DLigand-Gated ion ChannelLigand-Gated ion ChannelPredicted proteinLigand-Gated ion ChannelProton-gated ion channel subunit pbo-6Ligand-Gated ion ChannelLigand-Gated ion ChannelLigand-gated chloride channelUncharacterized protein, isoform FNicotinic acetylcholine receptor subunit alpha4Ligand-gated ion channel 4Histamine-gated chloride channel subunitLigand-Gated ion ChannelUncharacterized proteinGlutamate-gated chloride channel, putativeGlutamate-gated ChLoride channelLigand-Gated ion ChannelLOW QUALITY PROTEIN: 5-hydroxytryptamine receptor 3C-likeAcetylcholine-gated chloride channel subunit acc-1Ligand-Gated ion ChannelNicotinic acetylcholine receptor Dalpha7 subunitUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinGamma-aminobutyric acid receptor subunit gamma-3Acetylcholine-gated chloride channel subunit acc-3Gamma-aminobutyric acid receptor subunit alpha-4Uncharacterized proteinAcetylcholine receptor subunit alpha-type unc-63Ligand-Gated ion ChannelUncharacterized proteinAcetylCholine ReceptorLigand-Gated ion ChannelProbable ligand-gated ion channel 46NtR, isoform AGamma-aminobutyric acid type A receptor alpha6 subunitLigand-Gated ion ChannelUncharacterized proteingamma-aminobutyric acid receptor subunit rho-1-like isoform X2Gamma-aminobutyric acid type A receptor alpha2 subunitGamma-aminobutyric acid type A receptor alpha6 subunitcDNA FLJ56966, highly similar to Gamma-aminobutyric-acid receptor alpha-5 subunitUncharacterized proteinGamma-aminobutyric acid receptor subunit betaUncharacterized protein, isoform DNeuronal acetylcholine receptor subunit alpha-9Gamma-aminobutyric acid type A receptor rho1 subunitProtein CBR-LGC-28Uncharacterized proteinPredicted proteinPredicted proteinUncharacterized proteinNicotinic acetylcholine receptor a9 subunit splice variantSi:ch211-39a7.1Uncharacterized proteinLigand-Gated ion ChannelUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinGamma-aminobutyric acid type A receptor pi subunitLigand-Gated ion ChannelSi:ch73-380n15.2CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusionGH14445pAGAP010057-PAAcetylcholine receptor subunit alphaCholinergic receptor nicotinic epsilon subunitPredicted proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinPredicted proteinUncharacterized proteinUncharacterized proteinPredicted proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinPredicted proteinGlutamate-gated chloride channel, putativeUncharacterized proteinUncharacterized proteinUncharacterized proteinTransmembrane ion channelNicotinic acetylcholine receptor a10 subunit splice variantLigand-Gated ion Channelgamma-aminobutyric acid receptor subunit beta-3-likeTransmembrane ion channelTransmembrane ion channelProtein CBR-LGC-31Uncharacterized protein5-hydroxytryptamine receptor 3DLigand-Gated ion ChannelNicotinic acetylcholine receptor subunitCHRNA7-FAM7A fusion proteinUncharacterized proteinMacaca fascicularis brain cDNA clone: QflA-17345, similar to human cholinergic receptor, nicotinic, beta polypeptide 2(neuronal) (CHRNB2), mRNA, RefSeq: NM_000748.1Uncharacterized proteinUncharacterized proteinNicotinic acetylcyoline receptor Dalpha 4 subunitUncharacterized proteinCHRNA7-FAM7A fusion proteinPredicted proteinTransmembrane ion channelTransmembrane ion channelNeurotransmitter gated ion channel, putativeUncharacterized proteinNeurotransmitter gated ion channel, putativeProtein CBR-ACR-8Protein CBR-DEG-3Uncharacterized proteinProtein CBR-ACR-8Nicotinic acetylcholine receptor alpha 9 subunitUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinSi:ch211-256e16.10Uncharacterized proteinProtein CBR-DEG-3Glycine receptor alpha 2Uncharacterized proteinProtein CBG10414Neuronal acetylcholine receptor subunit alpha-3, putativeUncharacterized proteinPredicted proteinUncharacterized proteinUncharacterized proteinPredicted proteinPredicted proteinAGAP009493-PAUncharacterized proteinUncharacterized proteinUncharacterized proteinPredicted proteinUncharacterized proteinPredicted proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinGamma-aminobutyric acid type A receptor alpha2 subunit aUncharacterized proteinPredicted proteinUncharacterized proteinPredicted proteinGaba-gated chloride channel, putativeUncharacterized proteinUncharacterized proteinUncharacterized proteinGlutamate-gated chloride channel, putativeUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinProtein CBR-PBO-6Uncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinProtein CBR-EXP-1Predicted proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinGlycine receptor alpha 1 variant, putativeUncharacterized proteinPredicted proteinUncharacterized proteinUncharacterized proteinCholinergic receptor, nicotinic alpha 9Uncharacterized proteinUncharacterized proteinCholinergic receptor, nicotinic, beta 2Uncharacterized proteinCholinergic receptor nicotinic beta 1 subunitUncharacterized proteinCholinergic receptor nicotinic alpha 10 subunitNicotinic acetylcholine receptor subunitSoluble acetylcholine receptorUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinProtein CBG01602Uncharacterized proteinUncharacterized proteinProtein CBG24733Uncharacterized proteinPredicted proteinAcetylcholine receptor subunit deltaGABA receptor alpha 6 subunitUncharacterized proteinPredicted proteinGamma-aminobutyric acid (GABA) A receptor, rho 1Uncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinPredicted proteinSD10415pPredicted proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinProtein CBG01074Predicted proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinSi:ch211-39a7.1Uncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinCholinergic receptor, nicotinic, alpha 6Uncharacterized proteinProtein CBG26995Uncharacterized proteinUncharacterized proteinCholinergic receptor nicotinic alpha 10 subunitUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinProtein CBG01074Protein CBG26995Uncharacterized proteinUncharacterized proteinUncharacterized protein
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FunFam 108: Ligand-Gated ion Channel

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 0 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

There are 0 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
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