The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Mannose-6-phosphate receptor binding domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
SC:1protein OS-9 isoform X1Insulin-like growth factor 2 receptorInsulin-like growth factor 2 receptorCation-dependent mannose-6-phosphate receptorInsulin-like growth factor 2 receptorInsulin-like growth factor 2 receptorInsulin-like growth factor 2 receptorInsulin-like growth factor 2 receptorInsulin-like growth factor 2 receptorInsulin-like growth factor 2 receptorEndoplasmic reticulum lectin 1Endoplasmic reticulum lectin 1Insulin-like growth factor 2 receptorInsulin-like growth factor 2 receptorInsulin-like growth factor 2 receptorInsulin-like growth factor 2 receptorglucosidase 2 subunit beta isoform X1Insulin-like growth factor 2 receptorN-acetylglucosamine-1-phosphotransferase subunit gammaInsulin-like growth factor 2 receptorProtein OS-9 homologInsulin-like growth factor 2 receptorUPF0577 protein KIAA1324 homologPutative vacuolar sorting receptorProtein OS-9 homologcation-independent mannose-6-phosphate receptor isoform X2Glucosidase 2 subunit betaMannose-6-phosphate/insulin-like growth factor II receptoruncharacterized protein LOC100184158Endoplasmic reticulum lectin 1Yos9pLysosomal enzyme receptor proteinLysosomal enzyme receptor proteinGlucosidase II beta subunitAutophagy protein Atg27, putativeEndoplasmic reticulum lectin 1Lysosomal enzyme receptor proteinInsulin-like growth factor 2 receptorAGAP000998-PAEndoplasmic reticulum lectin 1-like isoform 2Protein OS-9 homologUncharacterized proteinInsulin like growth factor 2 receptorMannose 6-phosphate receptor domain-containing proteinPutative mannose-6-phosphate/insulin receptor type ii
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FunFam 26: cation-independent mannose-6-phosphate receptor is...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
4 A0A0B4KH68 (/IPI) B7Z0Q8 (/IPI) Q8IMR0 (/IPI) Q8IMR1 (/IPI)
Showing 1 to 1 of 1 entries

There are 3 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Post-Golgi vesicle-mediated transport GO:0006892
The directed movement of substances from the Golgi to other parts of the cell, including organelles and the plasma membrane, mediated by small transport vesicles.
4 A0A0B4KH68 (/IDA) B7Z0Q8 (/IDA) Q8IMR0 (/IDA) Q8IMR1 (/IDA)
Lysosomal transport GO:0007041
The directed movement of substances into, out of or within a lysosome.
4 A0A0B4KH68 (/IDA) B7Z0Q8 (/IDA) Q8IMR0 (/IDA) Q8IMR1 (/IDA)
Positive regulation of autophagy GO:0010508
Any process that activates, maintains or increases the rate of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.
4 A0A0B4KH68 (/IMP) B7Z0Q8 (/IMP) Q8IMR0 (/IMP) Q8IMR1 (/IMP)
Showing 1 to 3 of 3 entries

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
4 A0A0B4KH68 (/IC) B7Z0Q8 (/IC) Q8IMR0 (/IC) Q8IMR1 (/IC)
Trans-Golgi network GO:0005802
The network of interconnected tubular and cisternal structures located within the Golgi apparatus on the side distal to the endoplasmic reticulum, from which secretory vesicles emerge. The trans-Golgi network is important in the later stages of protein secretion where it is thought to play a key role in the sorting and targeting of secreted proteins to the correct destination.
4 A0A0B4KH68 (/IDA) B7Z0Q8 (/IDA) Q8IMR0 (/IDA) Q8IMR1 (/IDA)
Clathrin-coated vesicle GO:0030136
A vesicle with a coat formed of clathrin connected to the membrane via one of the clathrin adaptor complexes.
4 A0A0B4KH68 (/IDA) B7Z0Q8 (/IDA) Q8IMR0 (/IDA) Q8IMR1 (/IDA)
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
4 A0A0B4KH68 (/IDA) B7Z0Q8 (/IDA) Q8IMR0 (/IDA) Q8IMR1 (/IDA)
Showing 1 to 4 of 4 entries
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