The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Acid-sensing ion channels like domains
".
FunFam 3: Amiloride-sensitive sodium channel subunit beta
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 7 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
4 | P51168 (/IPI) P51168 (/IPI) Q9WU38 (/IPI) Q9WU38 (/IPI) |
|
WW domain binding GO:0050699
Interacting selectively and non-covalently with a WW domain of a protein, a small module composed of 40 amino acids and plays a role in mediating protein-protein interactions via proline-rich regions.
|
4 | P51168 (/IPI) P51168 (/IPI) Q9WU38 (/IPI) Q9WU38 (/IPI) |
|
Ligand-gated sodium channel activity GO:0015280
Enables the transmembrane transfer of a sodium ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.
|
2 | Q9WU38 (/IDA) Q9WU38 (/IDA) |
|
Ligand-gated sodium channel activity GO:0015280
Enables the transmembrane transfer of a sodium ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.
|
2 | Q9WU38 (/IGI) Q9WU38 (/IGI) |
|
Ligand-gated sodium channel activity GO:0015280
Enables the transmembrane transfer of a sodium ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.
|
2 | Q9WU38 (/ISO) Q9WU38 (/ISO) |
|
Ligand-gated sodium channel activity GO:0015280
Enables the transmembrane transfer of a sodium ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.
|
2 | P51168 (/TAS) P51168 (/TAS) |
|
WW domain binding GO:0050699
Interacting selectively and non-covalently with a WW domain of a protein, a small module composed of 40 amino acids and plays a role in mediating protein-protein interactions via proline-rich regions.
|
2 | Q9WU38 (/ISO) Q9WU38 (/ISO) |
There are 17 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Sodium ion transmembrane transport GO:0035725
A process in which a sodium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
|
7 | A5D7U4 (/ISS) H2QAR6 (/ISS) K7FQW8 (/ISS) O62816 (/ISS) O97742 (/ISS) P51169 (/ISS) Q95165 (/ISS) |
|
Multicellular organismal water homeostasis GO:0050891
Any process involved in the maintenance of an internal steady state of water within a tissue, organ, or a multicellular organism.
|
6 | O62816 (/ISS) O97742 (/ISS) P51169 (/ISS) Q95165 (/ISS) Q9WU38 (/ISS) Q9WU38 (/ISS) |
|
Sodium ion homeostasis GO:0055078
Any process involved in the maintenance of an internal steady state of sodium ions within an organism or cell.
|
6 | O62816 (/ISS) O97742 (/ISS) P51169 (/ISS) Q95165 (/ISS) Q9WU38 (/ISS) Q9WU38 (/ISS) |
|
Regulation of sodium ion transport GO:0002028
Any process that modulates the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
2 | Q9WU38 (/ISO) Q9WU38 (/ISO) |
|
Sodium ion transport GO:0006814
The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
2 | Q9WU38 (/IDA) Q9WU38 (/IDA) |
|
Sodium ion transport GO:0006814
The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
2 | Q9WU38 (/IGI) Q9WU38 (/IGI) |
|
Sodium ion transport GO:0006814
The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
2 | Q9WU38 (/ISO) Q9WU38 (/ISO) |
|
Sodium ion transport GO:0006814
The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
2 | P51168 (/TAS) P51168 (/TAS) |
|
Excretion GO:0007588
The elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds.
|
2 | P51168 (/TAS) P51168 (/TAS) |
|
Ion transmembrane transport GO:0034220
A process in which an ion is transported across a membrane.
|
2 | P51168 (/TAS) P51168 (/TAS) |
|
Wound healing, spreading of epidermal cells GO:0035313
The migration of an epidermal cell along or through a wound gap that contributes to the reestablishment of a continuous epidermis.
|
2 | Q9WU38 (/ISO) Q9WU38 (/ISO) |
|
Sodium ion transmembrane transport GO:0035725
A process in which a sodium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
|
2 | P51168 (/IDA) P51168 (/IDA) |
|
Sodium ion transmembrane transport GO:0035725
A process in which a sodium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
|
2 | Q9WU38 (/ISO) Q9WU38 (/ISO) |
|
Multicellular organismal water homeostasis GO:0050891
Any process involved in the maintenance of an internal steady state of water within a tissue, organ, or a multicellular organism.
|
2 | P51168 (/IDA) P51168 (/IDA) |
|
Multicellular organismal water homeostasis GO:0050891
Any process involved in the maintenance of an internal steady state of water within a tissue, organ, or a multicellular organism.
|
2 | Q9WU38 (/ISO) Q9WU38 (/ISO) |
|
Sodium ion homeostasis GO:0055078
Any process involved in the maintenance of an internal steady state of sodium ions within an organism or cell.
|
2 | P51168 (/IDA) P51168 (/IDA) |
|
Sodium ion homeostasis GO:0055078
Any process involved in the maintenance of an internal steady state of sodium ions within an organism or cell.
|
2 | Q9WU38 (/ISO) Q9WU38 (/ISO) |
There are 15 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
6 | O62816 (/ISS) O97742 (/ISS) P51169 (/ISS) Q95165 (/ISS) Q9WU38 (/ISS) Q9WU38 (/ISS) |
|
Sodium channel complex GO:0034706
An ion channel complex through which sodium ions pass.
|
4 | O62816 (/ISS) O97742 (/ISS) P51169 (/ISS) Q95165 (/ISS) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
2 | P51168 (/TAS) P51168 (/TAS) |
|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
2 | P51168 (/IDA) P51168 (/IDA) |
|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
2 | Q9WU38 (/ISO) Q9WU38 (/ISO) |
|
External side of plasma membrane GO:0009897
The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface.
|
2 | Q9WU38 (/IDA) Q9WU38 (/IDA) |
|
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
2 | Q9WU38 (/ISO) Q9WU38 (/ISO) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
2 | Q9WU38 (/IDA) Q9WU38 (/IDA) |
|
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
2 | Q9WU38 (/IDA) Q9WU38 (/IDA) |
|
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
|
2 | Q9WU38 (/ISO) Q9WU38 (/ISO) |
|
Sodium channel complex GO:0034706
An ion channel complex through which sodium ions pass.
|
2 | P51168 (/IDA) P51168 (/IDA) |
|
Sodium channel complex GO:0034706
An ion channel complex through which sodium ions pass.
|
2 | Q9WU38 (/IGI) Q9WU38 (/IGI) |
|
Sodium channel complex GO:0034706
An ion channel complex through which sodium ions pass.
|
2 | Q9WU38 (/ISO) Q9WU38 (/ISO) |
|
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
2 | P51168 (/IDA) P51168 (/IDA) |
|
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
2 | Q9WU38 (/ISO) Q9WU38 (/ISO) |
