The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 5: Arrestin domain-containing protein 3

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
5 Q8NCT1 (/IPI) Q8NCT1 (/IPI) Q96B67 (/IPI) Q96B67 (/IPI) Q96B67 (/IPI)
Beta-3 adrenergic receptor binding GO:0031699
Interacting selectively and non-covalently with a beta-3 adrenergic receptor.
3 Q96B67 (/IDA) Q96B67 (/IDA) Q96B67 (/IDA)
Protein binding, bridging involved in substrate recognition for ubiquitination GO:1990756
The binding activity of a molecule that brings together a ubiquitin ligase and its substrate. Usually mediated by F-box BTB/POZ domain proteins.
3 Q7TP90 (/ISS) Q8NCT1 (/ISS) Q8NCT1 (/ISS)
Beta-3 adrenergic receptor binding GO:0031699
Interacting selectively and non-covalently with a beta-3 adrenergic receptor.
1 Q7TPQ9 (/ISO)
Protein binding, bridging involved in substrate recognition for ubiquitination GO:1990756
The binding activity of a molecule that brings together a ubiquitin ligase and its substrate. Usually mediated by F-box BTB/POZ domain proteins.
1 A0A0B4J1F4 (/IMP)

There are 16 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Positive regulation of ubiquitin-protein transferase activity GO:0051443
Any process that activates, maintains or increases the rate of ubiquitin transferase activity.
5 Q8NCT1 (/IPI) Q8NCT1 (/IPI) Q96B67 (/IPI) Q96B67 (/IPI) Q96B67 (/IPI)
Negative regulation of cold-induced thermogenesis GO:0120163
Any process that stops, prevents, or reduces the rate of cold-induced thermogenesis.
4 Q6TXF1 (/ISS) Q96B67 (/ISS) Q96B67 (/ISS) Q96B67 (/ISS)
Protein transport GO:0015031
The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
3 Q7TP90 (/ISS) Q8NCT1 (/ISS) Q8NCT1 (/ISS)
Protein ubiquitination GO:0016567
The process in which one or more ubiquitin groups are added to a protein.
3 Q7TP90 (/ISS) Q8NCT1 (/ISS) Q8NCT1 (/ISS)
Extracellular vesicle biogenesis GO:0140112
The assembly and secretion a set of components to form an extracellular vesicule, a membrane-bounded vesicle that is released into the extracellular region. Extracellular vesicles include exosomes, microvesicles and apoptotic bodies, based on the mechanism by which they are released from cells and differentiated based on their size and content.
3 Q7TP90 (/ISS) Q8NCT1 (/ISS) Q8NCT1 (/ISS)
Positive regulation of ubiquitin-protein transferase activity GO:0051443
Any process that activates, maintains or increases the rate of ubiquitin transferase activity.
2 A0A0B4J1F4 (/ISO) Q7TPQ9 (/ISO)
Temperature homeostasis GO:0001659
A homeostatic process in which an organism modulates its internal body temperature.
1 Q7TPQ9 (/IMP)
Protein transport GO:0015031
The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 A0A0B4J1F4 (/IMP)
Protein ubiquitination GO:0016567
The process in which one or more ubiquitin groups are added to a protein.
1 A0A0B4J1F4 (/IMP)
Negative regulation of heat generation GO:0031651
Any process that stops, prevents, or reduces the rate or extent of heat generation.
1 Q7TPQ9 (/IMP)
Skin development GO:0043588
The process whose specific outcome is the progression of the skin over time, from its formation to the mature structure. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner vascular dermis (cutis, corium or true skin) composed mostly of connective tissue.
1 Q7TPQ9 (/IMP)
Fat pad development GO:0060613
The progression of a fat pad from its initial formation to its mature structure. A fat pad is an accumulation of adipose tissue.
1 Q7TPQ9 (/IMP)
Negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway GO:0071878
Any process that stops, prevents, or reduces the frequency, rate or extent of an adenylate cyclase-activating adrenergic receptor protein signaling pathway activity. An adrenergic receptor signaling pathway is the series of molecular signals generated as a consequence of an adrenergic receptor binding to one of its physiological ligands.
1 Q7TPQ9 (/IMP)
Negative regulation of locomotion involved in locomotory behavior GO:0090327
Any process that decreases the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement.
1 Q7TPQ9 (/IMP)
Negative regulation of cold-induced thermogenesis GO:0120163
Any process that stops, prevents, or reduces the rate of cold-induced thermogenesis.
1 Q7TPQ9 (/IMP)
Extracellular vesicle biogenesis GO:0140112
The assembly and secretion a set of components to form an extracellular vesicule, a membrane-bounded vesicle that is released into the extracellular region. Extracellular vesicles include exosomes, microvesicles and apoptotic bodies, based on the mechanism by which they are released from cells and differentiated based on their size and content.
1 A0A0B4J1F4 (/IMP)

There are 7 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
6 A0A0B4J1F4 (/IDA) Q8NCT1 (/IDA) Q8NCT1 (/IDA) Q96B67 (/IDA) Q96B67 (/IDA) Q96B67 (/IDA)
Endosome GO:0005768
A vacuole to which materials ingested by endocytosis are delivered.
5 Q8NCT1 (/IDA) Q8NCT1 (/IDA) Q96B67 (/IDA) Q96B67 (/IDA) Q96B67 (/IDA)
Extracellular vesicle GO:1903561
Any vesicle that is part of the extracellular region.
3 Q7TP90 (/ISS) Q8NCT1 (/ISS) Q8NCT1 (/ISS)
Endosome GO:0005768
A vacuole to which materials ingested by endocytosis are delivered.
2 A0A0B4J1F4 (/ISO) Q7TPQ9 (/ISO)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 A0A0B4J1F4 (/ISO) Q7TPQ9 (/ISO)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q7TP90 (/ISS)
Extracellular vesicle GO:1903561
Any vesicle that is part of the extracellular region.
1 A0A0B4J1F4 (/IDA)
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