The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
STAT transcription factor, DNA-binding domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 7: Signal transducer and activator of transcription 3

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 0 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

There are 20 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Skeletal system development GO:0001501
The process whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure. The skeleton is the bony framework of the body in vertebrates (endoskeleton) or the hard outer envelope of insects (exoskeleton or dermoskeleton).
1 Q7ZTS5 (/IMP)
Establishment of planar polarity GO:0001736
Coordinated organization of groups of cells in the plane of an epithelium, such that they all orient to similar coordinates.
1 Q7ZTS5 (/IMP)
Epithelial to mesenchymal transition GO:0001837
A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
1 Q7ZTS5 (/IMP)
Axis elongation GO:0003401
The developmental growth that results in the elongation of a line that defines polarity or symmetry in an anatomical structure.
1 Q7ZTS5 (/IMP)
Receptor signaling pathway via JAK-STAT GO:0007259
Any process in which STAT proteins (Signal Transducers and Activators of Transcription) and JAK (Janus Activated Kinase) proteins convey a signal to trigger a change in the activity or state of a cell. The receptor signaling pathway via JAK-STAT begins with activation of a receptor and proceeeds through STAT protein activation by members of the JAK family of tyrosine kinases. STAT proteins dimerize and subsequently translocate to the nucleus. The pathway ends with regulation of target gene expression by STAT proteins.
1 Q7ZTS5 (/IMP)
Motor neuron axon guidance GO:0008045
The process in which the migration of an axon growth cone of a motor neuron is directed to a specific target site in response to a combination of attractive and repulsive cues.
1 Q7ZTS5 (/IMP)
Cell population proliferation GO:0008283
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
1 Q7ZTS5 (/IMP)
Regulation of cell shape GO:0008360
Any process that modulates the surface configuration of a cell.
1 Q7ZTS5 (/IMP)
Regulation of cell size GO:0008361
Any process that modulates the size of a cell.
1 Q7ZTS5 (/IMP)
Establishment of cell polarity GO:0030010
The specification and formation of anisotropic intracellular organization or cell growth patterns.
1 Q7ZTS5 (/IMP)
Hemopoiesis GO:0030097
The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates.
1 Q8JFU8 (/IMP)
Regeneration GO:0031099
The regrowth of a lost or destroyed body part, such as an organ or tissue. This process may occur via renewal, repair, and/or growth alone (i.e. increase in size or mass).
1 Q7ZTS5 (/IGI)
Posterior lateral line neuromast hair cell development GO:0035677
The process whose specific outcome is the progression of a posterior lateral line neuromast hair cell over time, from its formation to the mature structure. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. Cell development does not include the steps involved in committing a cell to a specific fate.
1 Q7ZTS5 (/IMP)
Cell migration involved in gastrulation GO:0042074
The migration of individual cells within the blastocyst to help establish the multi-layered body plan of the organism (gastrulation). For example, the migration of cells from the surface to the interior of the embryo (ingression).
1 Q7ZTS5 (/IMP)
Regulation of cell population proliferation GO:0042127
Any process that modulates the frequency, rate or extent of cell proliferation.
1 Q7ZTS5 (/IMP)
Retina morphogenesis in camera-type eye GO:0060042
The process in which the anatomical structure of the retina is generated and organized.
1 Q7ZTS5 (/IMP)
Inner ear receptor cell development GO:0060119
The process whose specific outcome is the progression of an inner ear receptor cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.
1 Q7ZTS5 (/IMP)
Positive regulation of glial cell proliferation GO:0060252
Any process that activates or increases the rate or extent of glial cell proliferation.
1 Q7ZTS5 (/IMP)
Cardiac muscle tissue regeneration GO:0061026
The regrowth of cardiac muscle tissue to repair injured or damaged muscle fibers in the postnatal stage.
1 Q7ZTS5 (/IMP)
Hepatocyte differentiation GO:0070365
The process in which a relatively unspecialized cell acquires the specialized features of a hepatocyte. A hepatocyte is specialized epithelial cell that is organized into interconnected plates called lobules, and is the main structural component of the liver.
1 Q7ZTS5 (/IMP)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
CATH-Gene3D is a Global Biodata Core Resource Learn more...