The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Cadherins
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 9: Cadherin 24

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 10 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
3 P70407 (/IPI) P97291 (/IPI) Q3KNZ1 (/IPI)
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
1 Q86UP0 (/IDA)
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
1 Q6PFX6 (/ISO)
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
1 Q2MLR9 (/ISS)
Beta-catenin binding GO:0008013
Interacting selectively and non-covalently with the beta subunit of the catenin complex.
1 Q6PFX6 (/ISO)
Beta-catenin binding GO:0008013
Interacting selectively and non-covalently with the beta subunit of the catenin complex.
1 O93319 (/NAS)
Alpha-catenin binding GO:0045294
Interacting selectively and non-covalently with the alpha subunit of the catenin complex.
1 Q6PFX6 (/ISO)
Protein dimerization activity GO:0046983
The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits.
1 O93319 (/NAS)
Delta-catenin binding GO:0070097
Interacting selectively and non-covalently with the delta subunit of the catenin complex.
1 Q6PFX6 (/ISO)
Cadherin binding involved in cell-cell adhesion GO:0098641
Any cadherin binding that occurs as part of the process of cell-cell adhesion.
1 P70407 (/IPI)
Showing 1 to 10 of 10 entries

There are 46 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Adherens junction organization GO:0034332
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an adherens junction. An adherens junction is a cell junction at which the cytoplasmic face of the plasma membrane is attached to actin filaments.
16 P55285 (/TAS) P55286 (/TAS) P55286 (/TAS) P55286 (/TAS) P55287 (/TAS) P55289 (/TAS) Q13634 (/TAS) Q86UP0 (/TAS) Q9ULB4 (/TAS) Q9ULB5 (/TAS)
(6 more)
Cell-cell adhesion GO:0098609
The attachment of one cell to another cell via adhesion molecules.
9 O54800 (/NAS) Q9ULB4 (/NAS) Q9ULB5 (/NAS) Q9ULB5 (/NAS) Q9Y6N8 (/NAS) Q9Y6N8 (/NAS) Q9Y6N8 (/NAS) Q9Y6N8 (/NAS) Q9Y6N8 (/NAS)
Cell adhesion GO:0007155
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.
5 P55285 (/TAS) P55286 (/TAS) P55286 (/TAS) P55286 (/TAS) P55287 (/TAS)
Neural tube formation GO:0001841
The formation of a tube from the flat layer of ectodermal cells known as the neural plate. This will give rise to the central nervous system.
4 F1P1D3 (/IMP) F1P1D4 (/IMP) Q8AWW2 (/IMP) Q90763 (/IMP)
Neural crest cell delamination GO:0036032
The negative regulation of cell adhesion process in which a neural crest cell physically separates from the rest of the neural tube.
4 F1P1D3 (/IMP) F1P1D4 (/IMP) Q8AWW2 (/IMP) Q90763 (/IMP)
Synapse assembly GO:0007416
The aggregation, arrangement and bonding together of a set of components to form a synapse. This process ends when the synapse is mature (functional).
2 D3ZFQ5 (/IMP) P70407 (/IMP)
Notochord development GO:0030903
The process whose specific outcome is the progression of the notochord over time, from its formation to the mature structure. The notochord is a mesoderm-derived structure located ventral of the developing nerve cord. In vertebrates, the notochord serves as a core around which other mesodermal cells form the vertebrae. In the most primitive chordates, which lack vertebrae, the notochord persists as a substitute for a vertebral column.
2 B0S6D4 (/IMP) Q203V7 (/IMP)
Pronephros development GO:0048793
The process whose specific outcome is the progression of the pronephros over time, from its formation to the mature structure. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life.
2 Q5BKW2 (/IMP) Q5WN09 (/IMP)
Notochord cell differentiation GO:0060034
The process in which relatively unspecialized cells acquire specialized structural and/or functional features cells that make up the notochord. Differentiation includes the processes involved in commitment of a cell to a notochord cell fate.
2 B0S6D4 (/IMP) Q203V7 (/IMP)
Retina morphogenesis in camera-type eye GO:0060042
The process in which the anatomical structure of the retina is generated and organized.
2 Q5BKW2 (/IMP) Q5WN09 (/IMP)
Showing 1 to 10 of 46 entries

There are 33 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
16 P55285 (/TAS) P55286 (/TAS) P55286 (/TAS) P55286 (/TAS) P55287 (/TAS) P55289 (/TAS) Q13634 (/TAS) Q86UP0 (/TAS) Q9ULB4 (/TAS) Q9ULB5 (/TAS)
(6 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
7 F1P1D3 (/IDA) F1P1D4 (/IDA) O93319 (/IDA) P55288 (/IDA) P97326 (/IDA) Q8AWW2 (/IDA) Q90763 (/IDA)
Glutamatergic synapse GO:0098978
A synapse that uses glutamate as a neurotransmitter.
4 F1LR98 (/IDA) P55288 (/IDA) P70407 (/IDA) P97291 (/IDA)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
2 O54800 (/TAS) P55280 (/TAS)
Cell-cell junction GO:0005911
A cell junction that forms a connection between two or more cells in a multicellular organism; excludes direct cytoplasmic junctions such as ring canals.
2 O93319 (/IDA) Q86UP0 (/IDA)
Integral component of postsynaptic membrane GO:0099055
The component of the postsynaptic membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
2 D3ZFQ5 (/IDA) P70407 (/IDA)
Integral component of presynaptic membrane GO:0099056
The component of the presynaptic membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
2 D3ZFQ5 (/IDA) P70407 (/IDA)
Cell GO:0005623
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
1 Q90762 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 P55288 (/IDA)
Cell-cell junction GO:0005911
A cell junction that forms a connection between two or more cells in a multicellular organism; excludes direct cytoplasmic junctions such as ring canals.
1 Q6PFX6 (/ISO)
Showing 1 to 10 of 33 entries
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