The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Cadherins
".
FunFam 29: Cadherin EGF LAG seven-pass G-type receptor 3
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 9 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
7 | O35161 (/IPI) P33450 (/IPI) Q2PZL6 (/IPI) Q6V0I7 (/IPI) Q9NYQ7 (/IPI) Q9V5N8 (/IPI) Q9V5N8 (/IPI) |
Transmembrane signaling receptor activity GO:0004888
Combining with an extracellular or intracellular signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity or state as part of signal transduction.
|
3 | O35161 (/NAS) Q9V5N8 (/NAS) Q9V5N8 (/NAS) |
Cell adhesion molecule binding GO:0050839
Interacting selectively and non-covalently with a cell adhesion molecule.
|
2 | Q9V5N8 (/ISS) Q9V5N8 (/ISS) |
G protein-coupled receptor activity GO:0004930
Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
|
1 | O35161 (/NAS) |
G protein-coupled receptor activity GO:0004930
Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
|
1 | Q9NYQ7 (/TAS) |
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
|
1 | P33450 (/IDA) |
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
|
1 | O35161 (/TAS) |
Cadherin binding GO:0045296
Interacting selectively and non-covalently with cadherin, a type I membrane protein involved in cell adhesion.
|
1 | P33450 (/IPI) |
Protein dimerization activity GO:0046983
The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits.
|
1 | O35161 (/NAS) |
There are 128 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Cell migration involved in gastrulation GO:0042074
The migration of individual cells within the blastocyst to help establish the multi-layered body plan of the organism (gastrulation). For example, the migration of cells from the surface to the interior of the embryo (ingression).
|
5 | A0A286Y9U4 (/IGI) A0A2R8Q4B0 (/IGI) F1QBS8 (/IGI) F1QKG4 (/IGI) F1R9W4 (/IGI) |
Cell migration involved in gastrulation GO:0042074
The migration of individual cells within the blastocyst to help establish the multi-layered body plan of the organism (gastrulation). For example, the migration of cells from the surface to the interior of the embryo (ingression).
|
5 | A0A286Y9U4 (/IMP) A0A2R8Q4B0 (/IMP) F1QBS8 (/IMP) F1QKG4 (/IMP) F1R9W4 (/IMP) |
Establishment of planar polarity GO:0001736
Coordinated organization of groups of cells in the plane of an epithelium, such that they all orient to similar coordinates.
|
4 | O35161 (/IMP) P33450 (/IMP) Q9V5N8 (/IMP) Q9V5N8 (/IMP) |
Regulation of tube length, open tracheal system GO:0035159
Ensuring that a tube in an open tracheal system is of the correct length.
|
3 | P33450 (/IMP) Q9V5N8 (/IMP) Q9V5N8 (/IMP) |
Establishment of ommatidial planar polarity GO:0042067
The specification of polarized ommatidia. Ommatidia occur in two chiral forms. The trapezoidal arrangement of photoreceptors in the dorsal part of the eye is the mirror image of that in the ventral part.
|
3 | P33450 (/IMP) Q9V5N8 (/IMP) Q9V5N8 (/IMP) |
Dendrite morphogenesis GO:0048813
The process in which the anatomical structures of a dendrite are generated and organized.
|
3 | Q9QYP2 (/IMP) Q9V5N8 (/IMP) Q9V5N8 (/IMP) |
Wnt signaling pathway, planar cell polarity pathway GO:0060071
The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity.
|
3 | P33450 (/TAS) Q9V5N8 (/TAS) Q9V5N8 (/TAS) |
Cell-cell adhesion GO:0098609
The attachment of one cell to another cell via adhesion molecules.
|
3 | A0JBX1 (/IMP) F1QT64 (/IMP) P33450 (/IMP) |
Establishment of planar polarity GO:0001736
Coordinated organization of groups of cells in the plane of an epithelium, such that they all orient to similar coordinates.
|
2 | Q9V5N8 (/TAS) Q9V5N8 (/TAS) |
Morphogenesis of a polarized epithelium GO:0001738
The morphogenetic process in which the anatomical structures of a polarized epithelium are generated and organized. A polarized epithelium is an epithelium where the epithelial sheet is oriented with respect to the planar axis.
|
2 | Q9V5N8 (/IMP) Q9V5N8 (/IMP) |
Neuron migration GO:0001764
The characteristic movement of an immature neuron from germinal zones to specific positions where they will reside as they mature.
|
2 | O35161 (/IMP) Q91ZI0 (/IMP) |
Homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156
The attachment of a plasma membrane adhesion molecule in one cell to an identical molecule in an adjacent cell.
|
2 | Q9V5N8 (/IDA) Q9V5N8 (/IDA) |
Homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156
The attachment of a plasma membrane adhesion molecule in one cell to an identical molecule in an adjacent cell.
|
2 | Q9V5N8 (/TAS) Q9V5N8 (/TAS) |
Segment polarity determination GO:0007367
Division of the 14 parasegments of the embryo into anterior and posterior compartments; exemplified by the actions of the segment polarity gene products.
|
2 | Q9V5N8 (/IEP) Q9V5N8 (/IEP) |
Segment polarity determination GO:0007367
Division of the 14 parasegments of the embryo into anterior and posterior compartments; exemplified by the actions of the segment polarity gene products.
|
2 | Q9V5N8 (/IMP) Q9V5N8 (/IMP) |
Axonogenesis GO:0007409
De novo generation of a long process of a neuron, including the terminal branched region. Refers to the morphogenesis or creation of shape or form of the developing axon, which carries efferent (outgoing) action potentials from the cell body towards target cells.
|
2 | Q9V5N8 (/IMP) Q9V5N8 (/IMP) |
Axon guidance GO:0007411
The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.
|
2 | Q9V5N8 (/IMP) Q9V5N8 (/IMP) |
R3/R4 cell fate commitment GO:0007464
The process in which the R3/R4 photoreceptors commit to their cell fate. R3 and R4 are paired photoreceptors which contribute the outer rhabdomeres.
|
2 | Q9V5N8 (/NAS) Q9V5N8 (/NAS) |
Protein localization GO:0008104
Any process in which a protein is transported to, or maintained in, a specific location.
|
2 | A0JBX1 (/IGI) F1QT64 (/IGI) |
Ommatidial rotation GO:0016318
The process in which photoreceptors are arranged in ommatidia in the dorsal and ventral fields to be mirror images. The polarity is established in the imaginal discs concurrently with cell fate specification.
|
2 | Q9V5N8 (/IMP) Q9V5N8 (/IMP) |
Mushroom body development GO:0016319
The process whose specific outcome is the progression of the mushroom body over time, from its formation to the mature structure. The mushroom body is composed of the prominent neuropil structures of the insect central brain, thought to be crucial for olfactory associated learning. These consist mainly of a bulbous calyx and tightly packaged arrays of thin parallel fibers of the Kenyon cells.
|
2 | Q9V5N8 (/IMP) Q9V5N8 (/IMP) |
Calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules GO:0016339
The attachment of one cell to another cell via adhesion molecules that require the presence of calcium for the interaction.
|
2 | Q9V5N8 (/IMP) Q9V5N8 (/IMP) |
Dendrite development GO:0016358
The process whose specific outcome is the progression of the dendrite over time, from its formation to the mature structure.
|
2 | Q9V5N8 (/IEP) Q9V5N8 (/IEP) |
Facial nucleus development GO:0021754
The process whose specific outcome is the progression of the facial nucleus over time, from its formation to the mature structure.
|
2 | A0JBX1 (/IMP) F1QT64 (/IMP) |
Establishment of ommatidial planar polarity GO:0042067
The specification of polarized ommatidia. Ommatidia occur in two chiral forms. The trapezoidal arrangement of photoreceptors in the dorsal part of the eye is the mirror image of that in the ventral part.
|
2 | Q9V5N8 (/TAS) Q9V5N8 (/TAS) |
Positive regulation of axon extension GO:0045773
Any process that activates or increases the frequency, rate or extent of axon extension.
|
2 | Q9V5N8 (/IGI) Q9V5N8 (/IGI) |
R3/R4 development GO:0048057
The process whose specific outcome is the progression of the R3 and R4 pair of photoreceptors in the eye over time, from their formation to the mature structures. R3 and R4 are paired photoreceptors that contribute to the outer rhabdomeres. An example of this process is found in Drosophila melanogaster.
|
2 | Q9V5N8 (/IMP) Q9V5N8 (/IMP) |
Establishment of body hair planar orientation GO:0048105
Orientation of body hairs, projections from the surface of an organism, such that the hairs all point in a uniform direction along the surface.
|
2 | O35161 (/IMP) P33450 (/IMP) |
Dendrite morphogenesis GO:0048813
The process in which the anatomical structures of a dendrite are generated and organized.
|
2 | Q9V5N8 (/TAS) Q9V5N8 (/TAS) |
Regulation of axonogenesis GO:0050770
Any process that modulates the frequency, rate or extent of axonogenesis, the generation of an axon, the long process of a neuron.
|
2 | Q9V5N8 (/IDA) Q9V5N8 (/IDA) |
Regulation of synapse assembly GO:0051963
Any process that modulates the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse.
|
2 | Q9V5N8 (/IDA) Q9V5N8 (/IDA) |
Epiboly involved in gastrulation with mouth forming second GO:0055113
The expansion of one cell sheet over other cells involved in deuterostomic gastrulation.
|
2 | A0JBX1 (/IGI) F1QT64 (/IGI) |
Dendrite self-avoidance GO:0070593
The process in which dendrites recognize and avoid contact with sister dendrites from the same cell.
|
2 | Q9V5N8 (/IMP) Q9V5N8 (/IMP) |
Regulation of establishment of planar polarity GO:0090175
Any process that modulates the rate, frequency or extent of the establishment of planar polarity, the coordinated organization of groups of cells in a tissue, such that they all orient to similar coordinates.
|
2 | Q9V5N8 (/IGI) Q9V5N8 (/IGI) |
Cell-cell adhesion GO:0098609
The attachment of one cell to another cell via adhesion molecules.
|
2 | A0JBX1 (/IDA) F1QT64 (/IDA) |
Cell-cell adhesion GO:0098609
The attachment of one cell to another cell via adhesion molecules.
|
2 | A0JBX1 (/IGI) F1QT64 (/IGI) |
Positive regulation of axon guidance GO:1902669
Any process that activates or increases the frequency, rate or extent of axon guidance.
|
2 | Q9V5N8 (/IMP) Q9V5N8 (/IMP) |
Cell morphogenesis involved in differentiation GO:0000904
The change in form (cell shape and size) that occurs when relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.
|
1 | P33450 (/IMP) |
Branching involved in ureteric bud morphogenesis GO:0001658
The process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules.
|
1 | Q2PZL6 (/IMP) |
Gastrulation with mouth forming second GO:0001702
A gastrulation process in which the initial invagination becomes the anus and the mouth forms second.
|
1 | O35161 (/NAS) |
Establishment of planar polarity GO:0001736
Coordinated organization of groups of cells in the plane of an epithelium, such that they all orient to similar coordinates.
|
1 | Q2PZL6 (/IC) |
Establishment of planar polarity GO:0001736
Coordinated organization of groups of cells in the plane of an epithelium, such that they all orient to similar coordinates.
|
1 | P33450 (/IGI) |
Establishment of imaginal disc-derived wing hair orientation GO:0001737
Orientation of hairs in the imaginal disc-derived wing along a proximal-distal axis, such that each cell of the wing produces one wing hair which points in a distal direction.
|
1 | P33450 (/IMP) |
Kidney development GO:0001822
The process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and/or excretes the end products of body metabolism in the form of urine.
|
1 | Q2PZL6 (/IMP) |
Neural tube closure GO:0001843
The last step in the formation of the neural tube, where the paired neural folds are brought together and fuse at the dorsal midline.
|
1 | O35161 (/IGI) |
Neural tube closure GO:0001843
The last step in the formation of the neural tube, where the paired neural folds are brought together and fuse at the dorsal midline.
|
1 | O35161 (/IMP) |
Regulation of protein phosphorylation GO:0001932
Any process that modulates the frequency, rate or extent of addition of phosphate groups into an amino acid in a protein.
|
1 | Q91ZI0 (/IMP) |
Hair follicle development GO:0001942
The process whose specific outcome is the progression of the hair follicle over time, from its formation to the mature structure. A hair follicle is a tube-like opening in the epidermis where the hair shaft develops and into which the sebaceous glands open.
|
1 | O35161 (/IMP) |
Heart morphogenesis GO:0003007
The developmental process in which the heart is generated and organized. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
|
1 | Q2PZL6 (/IMP) |
Plasma membrane organization GO:0007009
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the plasma membrane.
|
1 | Q2PZL6 (/IMP) |
Heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules GO:0007157
The attachment of an adhesion molecule in one cell to a nonidentical adhesion molecule in an adjacent cell.
|
1 | Q2PZL6 (/IDA) |
Heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules GO:0007157
The attachment of an adhesion molecule in one cell to a nonidentical adhesion molecule in an adjacent cell.
|
1 | P33450 (/IPI) |
Heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules GO:0007157
The attachment of an adhesion molecule in one cell to a nonidentical adhesion molecule in an adjacent cell.
|
1 | Q6V0I7 (/ISS) |
Establishment of tissue polarity GO:0007164
Coordinated organization of groups of cells in a tissue, such that they all orient to similar coordinates.
|
1 | P33450 (/IMP) |
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
|
1 | O35161 (/NAS) |
G protein-coupled receptor signaling pathway GO:0007186
A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. The pathway can start from the plasma membrane, Golgi or nuclear membrane (PMID:24568158 and PMID:16902576).
|
1 | O35161 (/NAS) |
G protein-coupled receptor signaling pathway GO:0007186
A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. The pathway can start from the plasma membrane, Golgi or nuclear membrane (PMID:24568158 and PMID:16902576).
|
1 | Q9NYQ7 (/TAS) |
Gamma-aminobutyric acid signaling pathway GO:0007214
The series of molecular signals generated by the binding of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms, to a cell surface receptor.
|
1 | A9C3S7 (/IMP) |
Notch signaling pathway GO:0007219
A series of molecular signals initiated by the binding of an extracellular ligand to the receptor Notch on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
1 | Q2PZL6 (/IMP) |
Rho protein signal transduction GO:0007266
A series of molecular signals within the cell that are mediated by a member of the Rho family of proteins switching to a GTP-bound active state.
|
1 | O35161 (/IMP) |
Cell-cell signaling GO:0007267
Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions.
|
1 | O35161 (/NAS) |
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
|
1 | Q9QYP2 (/IEP) |
Axonal fasciculation GO:0007413
The collection of axons into a bundle of rods, known as a fascicle.
|
1 | Q91ZI0 (/IMP) |
Central nervous system development GO:0007417
The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.
|
1 | O35161 (/NAS) |
Imaginal disc growth GO:0007446
The increase in mass of imaginal discs by cell proliferation prior to metamorphosis. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult structures (legs, antennae, wings, etc.) during metamorphosis from larval to adult form.
|
1 | P33450 (/IMP) |
Imaginal disc pattern formation GO:0007447
The regionalization process that results in defined areas of the imaginal disc that will undergo specific cell differentaiton. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult appendages (legs, antennae, wings, etc.) during metamorphosis from larval to adult form.
|
1 | P33450 (/IMP) |
Imaginal disc-derived wing morphogenesis GO:0007476
The process in which the anatomical structures of the imaginal disc-derived wing are generated and organized. The wing is an appendage modified for flying.
|
1 | P33450 (/IMP) |
Locomotory behavior GO:0007626
The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions.
|
1 | O35161 (/IMP) |
Cell population proliferation GO:0008283
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
|
1 | P33450 (/IMP) |
Negative regulation of cell population proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
|
1 | P33450 (/IMP) |
Fibroblast growth factor receptor signaling pathway GO:0008543
The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands.
|
1 | Q2PZL6 (/IMP) |
Tissue development GO:0009888
The process whose specific outcome is the progression of a tissue over time, from its formation to the mature structure.
|
1 | P33450 (/IMP) |
Anterior/posterior pattern specification GO:0009952
The regionalization process in which specific areas of cell differentiation are determined along the anterior-posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.
|
1 | O35161 (/IMP) |
Negative regulation of gene expression GO:0010629
Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
1 | P33450 (/IMP) |
Establishment or maintenance of polarity of larval imaginal disc epithelium GO:0016336
Any cellular process that results in the specification, formation or maintenance of a polarized larval imaginal disc epithelium.
|
1 | P33450 (/IMP) |
Calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules GO:0016339
The attachment of one cell to another cell via adhesion molecules that require the presence of calcium for the interaction.
|
1 | P33450 (/IDA) |
Calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules GO:0016339
The attachment of one cell to another cell via adhesion molecules that require the presence of calcium for the interaction.
|
1 | P33450 (/NAS) |
Peptide cross-linking GO:0018149
The formation of a covalent cross-link between or within protein chains.
|
1 | P33450 (/IPI) |
Cerebral cortex development GO:0021987
The progression of the cerebral cortex over time from its initial formation until its mature state. The cerebral cortex is the outer layered region of the telencephalon.
|
1 | Q2PZL6 (/IMP) |
Cerebral cortex development GO:0021987
The progression of the cerebral cortex over time from its initial formation until its mature state. The cerebral cortex is the outer layered region of the telencephalon.
|
1 | Q6V0I7 (/ISS) |
Neurogenesis GO:0022008
Generation of cells within the nervous system.
|
1 | Q2PZL6 (/IMP) |
Neurogenesis GO:0022008
Generation of cells within the nervous system.
|
1 | Q6V0I7 (/ISS) |
Regulation of cell-cell adhesion GO:0022407
Any process that modulates the frequency, rate or extent of attachment of a cell to another cell.
|
1 | Q9QYP2 (/IMP) |
Regulation of protein localization GO:0032880
Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location.
|
1 | Q91ZI0 (/IGI) |
Regulation of protein localization GO:0032880
Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location.
|
1 | P33450 (/IMP) |
Regulation of actin cytoskeleton organization GO:0032956
Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.
|
1 | O35161 (/IMP) |
Pupal development GO:0035209
The process whose specific outcome is the progression of the pupa over time, from its formation to the mature structure. The pupa is a dormant life stage interposed between the larval and the adult stages in insects that undergo a complete metamorphosis.
|
1 | P33450 (/IMP) |
Wing disc development GO:0035220
Progression of the wing disc over time, from its initial formation through to its metamorphosis to form adult structures including the wing hinge, wing blade and pleura.
|
1 | P33450 (/IMP) |
Hippo signaling GO:0035329
The series of molecular signals mediated by the serine/threonine kinase Hippo or one of its orthologs. In Drosophila, Hippo in complex with the scaffold protein Salvador (Sav), phosphorylates and activates Warts (Wts), which in turn phosphorylates and inactivates the Yorkie (Yki) transcriptional activator. The core fly components hippo, sav, wts and mats are conserved in mammals as STK4/3 (MST1/2), SAV1/WW45, LATS1/2 and MOB1.
|
1 | Q2PZL6 (/IMP) |
Hippo signaling GO:0035329
The series of molecular signals mediated by the serine/threonine kinase Hippo or one of its orthologs. In Drosophila, Hippo in complex with the scaffold protein Salvador (Sav), phosphorylates and activates Warts (Wts), which in turn phosphorylates and inactivates the Yorkie (Yki) transcriptional activator. The core fly components hippo, sav, wts and mats are conserved in mammals as STK4/3 (MST1/2), SAV1/WW45, LATS1/2 and MOB1.
|
1 | Q6V0I7 (/ISS) |
Positive regulation of hippo signaling GO:0035332
Any process that activates or increases the frequency, rate or extent of hippo signaling.
|
1 | P33450 (/IGI) |
Positive regulation of hippo signaling GO:0035332
Any process that activates or increases the frequency, rate or extent of hippo signaling.
|
1 | P33450 (/IMP) |
Dopaminergic neuron axon guidance GO:0036514
The chemotaxis process that directs the migration of an axon growth cone of a dopaminergic neuron to a specific target site in response to a combination of attractive and repulsive cues.
|
1 | Q91ZI0 (/IMP) |
Serotonergic neuron axon guidance GO:0036515
The chemotaxis process that directs the migration of an axon growth cone of a serotonergic neuron to a specific target site in response to a combination of attractive and repulsive cues.
|
1 | Q91ZI0 (/IMP) |
Regulation of growth GO:0040008
Any process that modulates the frequency, rate or extent of the growth of all or part of an organism so that it occurs at its proper speed, either globally or in a specific part of the organism's development.
|
1 | P33450 (/IGI) |
Regulation of growth GO:0040008
Any process that modulates the frequency, rate or extent of the growth of all or part of an organism so that it occurs at its proper speed, either globally or in a specific part of the organism's development.
|
1 | P33450 (/IMP) |
Wound healing GO:0042060
The series of events that restore integrity to a damaged tissue, following an injury.
|
1 | O35161 (/IGI) |
Establishment of ommatidial planar polarity GO:0042067
The specification of polarized ommatidia. Ommatidia occur in two chiral forms. The trapezoidal arrangement of photoreceptors in the dorsal part of the eye is the mirror image of that in the ventral part.
|
1 | P33450 (/IGI) |
Establishment of planar polarity of embryonic epithelium GO:0042249
Coordinated organization of groups of cells in the plane of an embryonic epithelium, such that they all orient to similar coordinates.
|
1 | O35161 (/IMP) |
Inner ear morphogenesis GO:0042472
The process in which the anatomical structures of the inner ear are generated and organized. The inner ear is the structure in vertebrates that contains the organs of balance and hearing. It consists of soft hollow sensory structures (the membranous labyrinth) containing fluid (endolymph) surrounded by fluid (perilymph) and encased in a bony cavity (the bony labyrinth). It consists of two chambers, the sacculus and utriculus, from which arise the cochlea and semicircular canals respectively.
|
1 | O35161 (/IMP) |
Positive regulation of apoptotic process GO:0043065
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
|
1 | P33450 (/IMP) |
Ossification involved in bone maturation GO:0043931
The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone, involved in the progression of the skeleton from its formation to its mature state.
|
1 | Q2PZL6 (/IMP) |
Cell-cell adhesion mediated by cadherin GO:0044331
The attachment of one cell to another cell via a cadherin, transmembrane proteins having repeating extracellular calcium ion binding domains.
|
1 | P33450 (/IDA) |
Apical protein localization GO:0045176
Any process in which a protein is transported to, or maintained in, apical regions of the cell.
|
1 | O35161 (/IMP) |
Establishment of epithelial cell apical/basal polarity GO:0045198
The specification and formation of the apicobasal polarity of an epithelial cell.
|
1 | P33450 (/IMP) |
Equator specification GO:0045317
The formation and development of the equator that forms the boundary between the photoreceptors in the dorsal sector of the eye and those in the ventral sector, dividing the eye into dorsal and ventral halves.
|
1 | P33450 (/IMP) |
Regulation of imaginal disc growth GO:0045570
Any process that modulates the frequency, rate or extent of the growth of the imaginal disc.
|
1 | P33450 (/IMP) |
Negative regulation of imaginal disc growth GO:0045571
Any process that stops, prevents, or reduces the frequency, rate or extent of imaginal disc growth.
|
1 | P33450 (/IMP) |
Negative regulation of growth GO:0045926
Any process that stops, prevents or reduces the rate or extent of growth, the increase in size or mass of all or part of an organism.
|
1 | P33450 (/IMP) |
Negative regulation of organ growth GO:0046621
Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organ of an organism.
|
1 | P33450 (/IGI) |
Negative regulation of organ growth GO:0046621
Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organ of an organism.
|
1 | P33450 (/IMP) |
Regulation of neurotransmitter secretion GO:0046928
Any process that modulates the frequency, rate or extent of the regulated release of a neurotransmitter from a cell.
|
1 | O35161 (/NAS) |
Digestive tract development GO:0048565
The process whose specific outcome is the progression of the digestive tract over time, from its formation to the mature structure. The digestive tract is the anatomical structure through which food passes and is processed.
|
1 | Q2PZL6 (/IMP) |
Wnt signaling pathway, planar cell polarity pathway GO:0060071
The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity.
|
1 | Q9NYQ7 (/NAS) |
Inner ear receptor cell stereocilium organization GO:0060122
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a stereocilium. A stereocilium is an actin-based protrusion from the apical surface of inner ear receptor cells.
|
1 | Q2PZL6 (/IMP) |
Cilium assembly GO:0060271
The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.
|
1 | Q91ZI0 (/IGI) |
Orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis GO:0060488
The process in which a lung bud bifurcates perpendicular to the plane of the previous bud.
|
1 | O35161 (/IMP) |
Planar dichotomous subdivision of terminal units involved in lung branching morphogenesis GO:0060489
The process in which a lung bud bifurcates parallel to the plane of the previous bud.
|
1 | O35161 (/IMP) |
Lateral sprouting involved in lung morphogenesis GO:0060490
The process in which a branch forms along the side of the lung epithelial tube.
|
1 | O35161 (/IMP) |
Nephron development GO:0072006
The process whose specific outcome is the progression of the nephron over time, from its formation to the mature structure. A nephron is the functional unit of the kidney.
|
1 | Q2PZL6 (/IMP) |
Condensed mesenchymal cell proliferation GO:0072137
The multiplication or reproduction of cells, resulting in the expansion of a condensed mesenchymal cell population. A condensed mesenchymal cell population is a population of adherent mesenchymal cells.
|
1 | Q2PZL6 (/IGI) |
Condensed mesenchymal cell proliferation GO:0072137
The multiplication or reproduction of cells, resulting in the expansion of a condensed mesenchymal cell population. A condensed mesenchymal cell population is a population of adherent mesenchymal cells.
|
1 | Q2PZL6 (/IMP) |
Regulation of metanephric nephron tubule epithelial cell differentiation GO:0072307
Any process that modulates the frequency, rate or extent of metanephric nephron tubule epithelial cell differentiation.
|
1 | Q2PZL6 (/IMP) |
Microtubule cytoskeleton organization involved in establishment of planar polarity GO:0090176
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins and contributes to the establishment of planar polarity.
|
1 | P33450 (/IMP) |
Planar cell polarity pathway involved in neural tube closure GO:0090179
The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors that modulates the establishment of planar polarity contributing to neural tube closure.
|
1 | O35161 (/IGI) |
Protein localization involved in establishment of planar polarity GO:0090251
Any process in which a protein is transported to, and/or maintained in, a specific location in a cell that contributes to the establishment of planar polarity.
|
1 | O35161 (/IDA) |
Protein localization involved in establishment of planar polarity GO:0090251
Any process in which a protein is transported to, and/or maintained in, a specific location in a cell that contributes to the establishment of planar polarity.
|
1 | P33450 (/IMP) |
Planar cell polarity pathway involved in axon guidance GO:1904938
Any Wnt signaling pathway, planar cell polarity pathway that is involved in axon guidance.
|
1 | Q91ZI0 (/IMP) |
There are 17 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
3 | P33450 (/TAS) Q9V5N8 (/TAS) Q9V5N8 (/TAS) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
2 | A0JBX1 (/IDA) F1QT64 (/IDA) |
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
2 | Q9V5N8 (/ISS) Q9V5N8 (/ISS) |
Cell-cell junction GO:0005911
A cell junction that forms a connection between two or more cells in a multicellular organism; excludes direct cytoplasmic junctions such as ring canals.
|
2 | Q9V5N8 (/IDA) Q9V5N8 (/IDA) |
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
2 | Q9V5N8 (/ISM) Q9V5N8 (/ISM) |
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
2 | Q9V5N8 (/ISS) Q9V5N8 (/ISS) |
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
2 | Q9V5N8 (/NAS) Q9V5N8 (/NAS) |
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
2 | P33450 (/TAS) Q9NYQ7 (/TAS) |
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | O35161 (/ISO) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | O35161 (/ISO) |
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | P33450 (/IDA) |
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | P33450 (/NAS) |
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | O35161 (/TAS) |
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
1 | O35161 (/IDA) |
Apicolateral plasma membrane GO:0016327
The apical end of the lateral plasma membrane of epithelial cells.
|
1 | P33450 (/IDA) |
Apical part of cell GO:0045177
The region of a polarized cell that forms a tip or is distal to a base. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue.
|
1 | Q2PZL6 (/IDA) |
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
1 | Q6V0I7 (/HDA) |