The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Cadherins
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: Protocadherin alpha 2

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 12 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
28 A0A0A6YW27 (/IPI) A0A0A6YY37 (/IPI) A0A2R8RMH2 (/IPI) A9CPE6 (/IPI) B5TR11 (/IPI) F1QGL4 (/IPI) F7BJK1 (/IPI) F8W3H1 (/IPI) O14917 (/IPI) O88689 (/IPI)
(18 more)
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
10 A0A140LG84 (/IDA) A0A2R8QME5 (/IDA) A1L1W7 (/IDA) C4P340 (/IDA) C4P341 (/IDA) F8W3X3 (/IDA) O88689 (/IDA) Q91XZ2 (/IDA) Q91XZ4 (/IDA) Q91Y13 (/IDA)
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
10 Q5DRC6 (/ISS) Q5DRC8 (/ISS) Q5DRE5 (/ISS) Q5DRE8 (/ISS) Q767I8 (/ISS) Q767I8 (/ISS) Q9UN66 (/ISS) Q9UN72 (/ISS) Q9UN74 (/ISS) Q9Y5E3 (/ISS)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
10 Q5DRC6 (/ISS) Q5DRC8 (/ISS) Q5DRE5 (/ISS) Q5DRE8 (/ISS) Q767I8 (/ISS) Q767I8 (/ISS) Q9UN66 (/ISS) Q9UN72 (/ISS) Q9UN74 (/ISS) Q9Y5E3 (/ISS)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
6 A0A140LG84 (/IDA) A0A2R8QME5 (/IDA) A1L1W7 (/IDA) C4P340 (/IDA) C4P341 (/IDA) F8W3X3 (/IDA)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
4 O88689 (/IDA) Q91XZ2 (/IDA) Q91XZ4 (/IDA) Q91Y13 (/IDA)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
2 Q8N6Y1 (/HDA) Q9Y5G4 (/HDA)
Transmembrane transporter activity GO:0022857
Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other.
2 F1QUS2 (/IMP) Q6QQE1 (/IMP)
Frizzled binding GO:0005109
Interacting selectively and non-covalently with a frizzled (fz) receptor.
1 O93509 (/IPI)
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
1 Q8VHR0 (/NAS)
Protein N-terminus binding GO:0047485
Interacting selectively and non-covalently with a protein N-terminus, the end of any peptide chain at which the 2-amino (or 2-imino) function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue.
1 P58365 (/IPI)
Protein N-terminus binding GO:0047485
Interacting selectively and non-covalently with a protein N-terminus, the end of any peptide chain at which the 2-amino (or 2-imino) function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue.
1 Q99PF4 (/ISO)

There are 86 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cell adhesion GO:0007155
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.
23 Q6ZQD4 (/TAS) Q91Y16 (/TAS) Q99PF4 (/TAS) Q9H158 (/TAS) Q9UN71 (/TAS) Q9UN72 (/TAS) Q9UN73 (/TAS) Q9UN74 (/TAS) Q9Y5E3 (/TAS) Q9Y5E5 (/TAS)
(13 more)
Nervous system development GO:0007399
The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.
19 Q9H158 (/TAS) Q9UN72 (/TAS) Q9UN73 (/TAS) Q9UN74 (/TAS) Q9Y5E3 (/TAS) Q9Y5E5 (/TAS) Q9Y5E6 (/TAS) Q9Y5E7 (/TAS) Q9Y5E8 (/TAS) Q9Y5F1 (/TAS)
(9 more)
Calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules GO:0016339
The attachment of one cell to another cell via adhesion molecules that require the presence of calcium for the interaction.
16 Q91Y03 (/NAS) Q9H251 (/NAS) Q9HAB4 (/NAS) Q9NRJ7 (/NAS) Q9UN67 (/NAS) Q9UN70 (/NAS) Q9UN71 (/NAS) Q9Y5E1 (/NAS) Q9Y5E3 (/NAS) Q9Y5E4 (/NAS)
(6 more)
Chemical synaptic transmission GO:0007268
The vesicular release of classical neurotransmitter molecules from a presynapse, across a chemical synapse, the subsequent activation of neurotransmitter receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
13 Q91Y03 (/TAS) Q9HAB4 (/TAS) Q9NRJ7 (/TAS) Q9UN67 (/TAS) Q9Y5E1 (/TAS) Q9Y5E3 (/TAS) Q9Y5E4 (/TAS) Q9Y5E5 (/TAS) Q9Y5E6 (/TAS) Q9Y5E7 (/TAS)
(3 more)
Synapse assembly GO:0007416
The aggregation, arrangement and bonding together of a set of components to form a synapse. This process ends when the synapse is mature (functional).
13 Q91Y03 (/TAS) Q9HAB4 (/TAS) Q9NRJ7 (/TAS) Q9UN67 (/TAS) Q9Y5E1 (/TAS) Q9Y5E3 (/TAS) Q9Y5E4 (/TAS) Q9Y5E5 (/TAS) Q9Y5E6 (/TAS) Q9Y5E7 (/TAS)
(3 more)
Homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156
The attachment of a plasma membrane adhesion molecule in one cell to an identical molecule in an adjacent cell.
10 E9PX28 (/IDA) E9PXQ7 (/IDA) O55134 (/IDA) Q3TZ28 (/IDA) Q6P0A6 (/IDA) Q80TE2 (/IDA) Q91XZ4 (/IDA) Q91Y13 (/IDA) Q925I8 (/IDA) Q9Z1B1 (/IDA)
Cell adhesion GO:0007155
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.
7 E9PX28 (/IDA) E9PXQ7 (/IDA) Q3TZ28 (/IDA) Q6P0A6 (/IDA) Q80TE2 (/IDA) Q925I8 (/IDA) Q9Z1B1 (/IDA)
Neural tube formation GO:0001841
The formation of a tube from the flat layer of ectodermal cells known as the neural plate. This will give rise to the central nervous system.
6 A0A140LG84 (/IMP) A0A2R8QME5 (/IMP) A1L1W7 (/IMP) C4P340 (/IMP) C4P341 (/IMP) F8W3X3 (/IMP)
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
6 F1MA46 (/NAS) I6LBW8 (/NAS) I6LBX8 (/NAS) Q767I2 (/NAS) Q767I4 (/NAS) Q767I9 (/NAS)
Visual perception GO:0007601
The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual stimuli are detected in the form of photons and are processed to form an image.
6 A0A140LG84 (/IMP) A0A2R8QME5 (/IMP) A1L1W7 (/IMP) C4P340 (/IMP) C4P341 (/IMP) F8W3X3 (/IMP)
Brain morphogenesis GO:0048854
The process in which the anatomical structures of the brain are generated and organized. The brain is one of the two components of the central nervous system and is the center of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
6 A0A140LG84 (/IMP) A0A2R8QME5 (/IMP) A1L1W7 (/IMP) C4P340 (/IMP) C4P341 (/IMP) F8W3X3 (/IMP)
Synapse organization GO:0050808
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).
5 Q3UTF9 (/IGI) Q8K4A2 (/IGI) Q91XW9 (/IGI) Q91XX0 (/IGI) Q91XX1 (/IGI)
Somitogenesis GO:0001756
The formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo.
4 A0A0B5JW50 (/IMP) Q6IS19 (/IMP) Q7TSK3 (/IMP) Q805F0 (/IMP)
Homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156
The attachment of a plasma membrane adhesion molecule in one cell to an identical molecule in an adjacent cell.
4 Q5DRC8 (/ISS) Q5DRE5 (/ISS) Q9UN72 (/ISS) Q9Y5E3 (/ISS)
Sensory perception of sound GO:0007605
The series of events required for an organism to receive an auditory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Sonic stimuli are detected in the form of vibrations and are processed to form a sound.
4 F1QUS2 (/IMP) Q6QQE1 (/IMP) Q99PF4 (/IMP) Q9H251 (/IMP)
Cell-cell recognition GO:0009988
Cell recognition between cells. May involve the formation of specialized cell junctions.
4 Q5DRC8 (/ISS) Q5DRE5 (/ISS) Q9UN72 (/ISS) Q9Y5E3 (/ISS)
Calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules GO:0016339
The attachment of one cell to another cell via adhesion molecules that require the presence of calcium for the interaction.
4 A0A0B5JFG8 (/IMP) A0A2R8Q566 (/IMP) A9QUV5 (/IMP) F1QRP2 (/IMP)
Calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules GO:0016339
The attachment of one cell to another cell via adhesion molecules that require the presence of calcium for the interaction.
4 Q6NXW8 (/ISS) Q91XY7 (/ISS) Q99PF4 (/ISS) Q9Z1B0 (/ISS)
Cell migration involved in gastrulation GO:0042074
The migration of individual cells within the blastocyst to help establish the multi-layered body plan of the organism (gastrulation). For example, the migration of cells from the surface to the interior of the embryo (ingression).
4 A0A0B5JFG8 (/IMP) A0A2R8Q566 (/IMP) A9QUV5 (/IMP) F1QRP2 (/IMP)
Neuron projection morphogenesis GO:0048812
The process in which the anatomical structures of a neuron projection are generated and organized. A neuron projection is any process extending from a neural cell, such as axons or dendrites.
4 A0A2R8RMH2 (/IMP) A9CPE6 (/IMP) F1QGL4 (/IMP) F8W3H1 (/IMP)
Epiboly involved in gastrulation with mouth forming second GO:0055113
The expansion of one cell sheet over other cells involved in deuterostomic gastrulation.
4 A0A0B5JFG8 (/IMP) A0A2R8Q566 (/IMP) A9QUV5 (/IMP) F1QRP2 (/IMP)
Brain development GO:0007420
The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
3 A7MB46 (/ISS) Q9HCL0 (/ISS) Q9HCL0 (/ISS)
Thalamus development GO:0021794
The process in which the thalamus changes over time, from its initial formation to its mature state.
3 A0A0B5JW50 (/IMP) Q6IS19 (/IMP) Q805F0 (/IMP)
Adult behavior GO:0030534
Behavior in a fully developed and mature organism.
3 E9PXF0 (/IMP) Q3UTP0 (/IMP) Q5HZI5 (/IMP)
Odontogenesis GO:0042476
The process whose specific outcome is the progression of a tooth or teeth over time, from formation to the mature structure(s). A tooth is any hard bony, calcareous, or chitinous organ found in the mouth or pharynx of an animal and used in procuring or masticating food.
3 I6LBW4 (/NAS) Q767I8 (/NAS) Q767I8 (/NAS)
Paraxial mesoderm development GO:0048339
The process whose specific outcome is the progression of the paraxial mesoderm over time, from its formation to the mature structure. The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube.
3 A0A0B5JW50 (/IMP) Q6IS19 (/IMP) Q805F0 (/IMP)
Negative regulation of synaptic transmission GO:0050805
Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.
3 E9PXF0 (/IMP) Q3UTP0 (/IMP) Q5HZI5 (/IMP)
Equilibrioception GO:0050957
The series of events required for an organism to receive an orientational stimulus, convert it to a molecular signal, and recognize and characterize the signal. Equilibrioception refers to a combination of processes by which an organism can perceive its orientation with respect to gravity. In animals, stimuli come from labyrinth system of the inner ears, monitoring the direction of motion; visual stimuli, with information on orientation and motion; pressure receptors, which tell the organism which body surfaces are in contact with the ground; and proprioceptive cues, which report which parts of the body are in motion.
3 F1QUS2 (/IMP) Q6QQE1 (/IMP) Q9H251 (/IMP)
Inner ear receptor cell stereocilium organization GO:0060122
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a stereocilium. A stereocilium is an actin-based protrusion from the apical surface of inner ear receptor cells.
3 F1QUS2 (/IMP) Q6QQE1 (/IMP) Q99PF4 (/IMP)
Synaptic membrane adhesion GO:0099560
The attachment of presynaptic membrane to postsynaptic membrane via adhesion molecules that are at least partially embedded in the plasma membrane.
3 E9PXF0 (/IDA) Q3UTP0 (/IDA) Q5HZI5 (/IDA)
Synaptic membrane adhesion GO:0099560
The attachment of presynaptic membrane to postsynaptic membrane via adhesion molecules that are at least partially embedded in the plasma membrane.
3 E9PXF0 (/IMP) Q3UTP0 (/IMP) Q5HZI5 (/IMP)
Presynaptic active zone assembly GO:1904071
The aggregation, arrangement and bonding together of a set of components to form a presynaptic active zone. The presynaptic active zone is a specialized region of the plasma membrane and cell cortex of a presynaptic neuron; encompasses a region of the plasma membrane where synaptic vesicles dock and fuse, and a specialized cortical cytoskeletal matrix.
3 E9PXF0 (/IMP) Q3UTP0 (/IMP) Q5HZI5 (/IMP)
Regulation of synaptic vesicle clustering GO:2000807
Any process that modulates the frequency, rate or extent of synaptic vesicle clustering.
3 E9PXF0 (/IMP) Q3UTP0 (/IMP) Q5HZI5 (/IMP)
Endocytosis GO:0006897
A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.
2 F1QUS2 (/IMP) Q6QQE1 (/IMP)
Homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156
The attachment of a plasma membrane adhesion molecule in one cell to an identical molecule in an adjacent cell.
2 O88689 (/IC) Q91XZ2 (/IC)
Homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156
The attachment of a plasma membrane adhesion molecule in one cell to an identical molecule in an adjacent cell.
2 F7BJK1 (/TAS) Q91XX1 (/TAS)
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
2 F1LRA0 (/IEP) I6LBX6 (/IEP)
Axon guidance GO:0007411
The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.
2 A0A0B5JFA0 (/IMP) C4P342 (/IMP)
Cell-cell recognition GO:0009988
Cell recognition between cells. May involve the formation of specialized cell junctions.
2 Q91XZ4 (/IDA) Q91Y13 (/IDA)
Calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules GO:0016339
The attachment of one cell to another cell via adhesion molecules that require the presence of calcium for the interaction.
2 F7BJK1 (/TAS) Q91XX1 (/TAS)
Cell projection organization GO:0030030
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon.
2 F1QUS2 (/IMP) Q6QQE1 (/IMP)
Hair cell differentiation GO:0035315
The process in which a relatively unspecialized cell acquires specialized features of a hair cell.
2 F1QUS2 (/IMP) Q6QQE1 (/IMP)
Neuromast hair cell morphogenesis GO:0035678
The change in form (cell shape and size) that occurs when a neuromast hair cell progresses from its initial formation to its mature state. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface.
2 F1QUS2 (/IMP) Q6QQE1 (/IMP)
Axon extension GO:0048675
Long distance growth of a single axon process involved in cellular development.
2 A0A0B5JFA0 (/IMP) C4P342 (/IMP)
Sensory perception of light stimulus GO:0050953
The series of events required for an organism to receive a sensory light stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.
2 Q99PF4 (/IMP) Q9H251 (/IMP)
Detection of mechanical stimulus involved in sensory perception GO:0050974
The series of events in which a mechanical stimulus is received and converted into a molecular signal as part of sensory perception.
2 F1QUS2 (/IMP) Q6QQE1 (/IMP)
Retina development in camera-type eye GO:0060041
The process whose specific outcome is the progression of the retina over time, from its formation to the mature structure. The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates.
2 A0A0B5JFA0 (/IMP) C4P342 (/IMP)
Auditory receptor cell development GO:0060117
The process whose specific outcome is the progression of an auditory receptor cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.
2 F1QUS2 (/IMP) Q6QQE1 (/IMP)
Camera-type eye photoreceptor cell differentiation GO:0060219
The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell in a camera-type eye.
2 A0A0B5JFA0 (/IMP) C4P342 (/IMP)
Protein localization to cilium GO:0061512
A process in which a protein is transported to, or maintained in, a location within a cilium.
2 F1QUS2 (/IMP) Q6QQE1 (/IMP)
Glycogen metabolic process GO:0005977
The chemical reactions and pathways involving glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues in alpha-(1->4) glycosidic linkage, joined together by alpha-(1->6) glycosidic linkages.
1 O55134 (/IMP)
Calcium ion transport GO:0006816
The directed movement of calcium (Ca) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 Q9H251 (/IMP)
Calcium ion transport GO:0006816
The directed movement of calcium (Ca) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 Q99PF4 (/ISO)
Homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156
The attachment of a plasma membrane adhesion molecule in one cell to an identical molecule in an adjacent cell.
1 Q8VHR0 (/NAS)
Cell-cell signaling GO:0007267
Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions.
1 O95206 (/TAS)
Chemical synaptic transmission GO:0007268
The vesicular release of classical neurotransmitter molecules from a presynapse, across a chemical synapse, the subsequent activation of neurotransmitter receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
1 D3ZE55 (/IDA)
Chemical synaptic transmission GO:0007268
The vesicular release of classical neurotransmitter molecules from a presynapse, across a chemical synapse, the subsequent activation of neurotransmitter receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
1 Q7TSK3 (/ISO)
Brain development GO:0007420
The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
1 Q8VHR0 (/IEP)
Sensory perception of sound GO:0007605
The series of events required for an organism to receive an auditory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Sonic stimuli are detected in the form of vibrations and are processed to form a sound.
1 Q99PF4 (/IGI)
Sensory perception of sound GO:0007605
The series of events required for an organism to receive an auditory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Sonic stimuli are detected in the form of vibrations and are processed to form a sound.
1 Q99PF4 (/ISO)
Long-term memory GO:0007616
The memory process that deals with the storage, retrieval and modification of information a long time (typically weeks, months or years) after receiving that information. This type of memory is typically dependent on gene transcription regulated by second messenger activation.
1 D3ZE55 (/TAS)
Locomotory behavior GO:0007626
The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions.
1 Q99PF4 (/IMP)
Neuron recognition GO:0008038
The process in which a neuronal cell in a multicellular organism interprets its surroundings.
1 Q9NPG4 (/TAS)
Endosome to lysosome transport GO:0008333
The directed movement of substances from endosomes to lysosomes.
1 Q91XY5 (/IMP)
Morphogenesis of embryonic epithelium GO:0016331
The process in which the anatomical structures of embryonic epithelia are generated and organized.
1 Q7TSK3 (/IMP)
Calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules GO:0016339
The attachment of one cell to another cell via adhesion molecules that require the presence of calcium for the interaction.
1 O55134 (/IDA)
Calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules GO:0016339
The attachment of one cell to another cell via adhesion molecules that require the presence of calcium for the interaction.
1 Q8VHR0 (/ISO)
Inner ear morphogenesis GO:0042472
The process in which the anatomical structures of the inner ear are generated and organized. The inner ear is the structure in vertebrates that contains the organs of balance and hearing. It consists of soft hollow sensory structures (the membranous labyrinth) containing fluid (endolymph) surrounded by fluid (perilymph) and encased in a bony cavity (the bony labyrinth). It consists of two chambers, the sacculus and utriculus, from which arise the cochlea and semicircular canals respectively.
1 Q99PF4 (/IMP)
Inner ear auditory receptor cell differentiation GO:0042491
The process in which a relatively unspecialized inner cell acquires specialized features of an auditory hair cell.
1 Q99PF4 (/IMP)
Photoreceptor cell maintenance GO:0045494
Any process preventing the degeneration of the photoreceptor, a specialized cell type that is sensitive to light.
1 Q9H251 (/IMP)
Photoreceptor cell maintenance GO:0045494
Any process preventing the degeneration of the photoreceptor, a specialized cell type that is sensitive to light.
1 Q99PF4 (/ISO)
Post-embryonic animal organ morphogenesis GO:0048563
Morphogenesis, during the post-embryonic phase, of an animal tissue or tissues that work together to perform a specific function or functions. Morphogenesis pertains to process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
1 Q99PF4 (/IMP)
Inner ear development GO:0048839
The process whose specific outcome is the progression of the inner ear over time, from its formation to the mature structure.
1 Q99PF4 (/IMP)
Modulation of chemical synaptic transmission GO:0050804
Any process that modulates the frequency or amplitude of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse. Amplitude, in this case, refers to the change in postsynaptic membrane potential due to a single instance of synaptic transmission.
1 D3ZE55 (/EXP)
Modulation of chemical synaptic transmission GO:0050804
Any process that modulates the frequency or amplitude of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse. Amplitude, in this case, refers to the change in postsynaptic membrane potential due to a single instance of synaptic transmission.
1 Q7TSK3 (/ISO)
Sensory perception of light stimulus GO:0050953
The series of events required for an organism to receive a sensory light stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.
1 Q99PF4 (/ISO)
Equilibrioception GO:0050957
The series of events required for an organism to receive an orientational stimulus, convert it to a molecular signal, and recognize and characterize the signal. Equilibrioception refers to a combination of processes by which an organism can perceive its orientation with respect to gravity. In animals, stimuli come from labyrinth system of the inner ears, monitoring the direction of motion; visual stimuli, with information on orientation and motion; pressure receptors, which tell the organism which body surfaces are in contact with the ground; and proprioceptive cues, which report which parts of the body are in motion.
1 Q99PF4 (/ISO)
Regulation of cytosolic calcium ion concentration GO:0051480
Any process involved in the maintenance of an internal steady state of calcium ions within the cytosol of a cell or between the cytosol and its surroundings.
1 Q9H251 (/IMP)
Regulation of cytosolic calcium ion concentration GO:0051480
Any process involved in the maintenance of an internal steady state of calcium ions within the cytosol of a cell or between the cytosol and its surroundings.
1 Q99PF4 (/ISO)
Auditory receptor cell stereocilium organization GO:0060088
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a stereocilium. A stereocilium is an actin-based protrusion from the apical surface of auditory hair cells.
1 Q99PF4 (/IGI)
Auditory receptor cell stereocilium organization GO:0060088
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a stereocilium. A stereocilium is an actin-based protrusion from the apical surface of auditory hair cells.
1 Q99PF4 (/IMP)
Labyrinthine layer development GO:0060711
The process in which the labyrinthine layer of the placenta progresses, from its formation to its mature state.
1 O55134 (/IMP)
Lipid tube assembly involved in organelle fusion GO:0060989
The aggregation, arrangement and bonding together of a set of macromolecules to form a macromolecular complex that contains a tube of lipid surrounded by a protein coat involved in membrane shaping of vesicle membranes as organelles fuse.
1 Q91XY5 (/IMP)
Regulation of synaptic membrane adhesion GO:0099179
Any process that modulates the frequency, rate or extent of adhesion between pre- and post-synaptic membranes.
1 D3ZE55 (/IDA)
Regulation of synaptic membrane adhesion GO:0099179
Any process that modulates the frequency, rate or extent of adhesion between pre- and post-synaptic membranes.
1 D3ZE55 (/IMP)
Regulation of synaptic membrane adhesion GO:0099179
Any process that modulates the frequency, rate or extent of adhesion between pre- and post-synaptic membranes.
1 Q7TSK3 (/ISO)

There are 51 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
56 A0A0A6YW27 (/IDA) A0A0A6YXT1 (/IDA) A0A0A6YY44 (/IDA) B9EKB6 (/IDA) O88192 (/IDA) O88193 (/IDA) O88689 (/IDA) O88690 (/IDA) Q3UTF9 (/IDA) Q5DTQ9 (/IDA)
(46 more)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
25 F7BJK1 (/TAS) O95206 (/TAS) Q767H8 (/TAS) Q767I5 (/TAS) Q91XX1 (/TAS) Q9H158 (/TAS) Q9NPG4 (/TAS) Q9UN72 (/TAS) Q9UN73 (/TAS) Q9UN74 (/TAS)
(15 more)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
16 A0A0A6YY37 (/ISS) A0PJT6 (/ISS) E9PX28 (/ISS) E9PXQ7 (/ISS) O55134 (/ISS) Q3TZ28 (/ISS) Q5DRC8 (/ISS) Q5DRE5 (/ISS) Q6P0A6 (/ISS) Q7TSK3 (/ISS)
(6 more)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
13 Q91Y03 (/NAS) Q9HAB4 (/NAS) Q9NRJ7 (/NAS) Q9UN67 (/NAS) Q9Y5E1 (/NAS) Q9Y5E3 (/NAS) Q9Y5E4 (/NAS) Q9Y5E5 (/NAS) Q9Y5E6 (/NAS) Q9Y5E7 (/NAS)
(3 more)
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
6 B9EJ92 (/IDA) O88689 (/IDA) Q05C01 (/IDA) Q641K6 (/IDA) Q91Y17 (/IDA) Q91Y21 (/IDA)
Cell-cell junction GO:0005911
A cell junction that forms a connection between two or more cells in a multicellular organism; excludes direct cytoplasmic junctions such as ring canals.
6 A0PJT6 (/IDA) O55134 (/IDA) Q6NXW8 (/IDA) Q91XY7 (/IDA) Q91Y07 (/IDA) Q9Z1B0 (/IDA)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
6 A0A140LG84 (/IDA) A0A2R8QME5 (/IDA) A1L1W7 (/IDA) C4P340 (/IDA) C4P341 (/IDA) F8W3X3 (/IDA)
Photoreceptor connecting cilium GO:0032391
The portion of the photoreceptor cell cilium linking the photoreceptor inner and outer segments. It's considered to be equivalent to the ciliary transition zone.
6 Q14BM8 (/IDA) Q8C8Z3 (/IDA) Q8CB45 (/IDA) Q91XZ8 (/IDA) Q91Y03 (/IDA) Q925L0 (/IDA)
Synapse GO:0045202
The junction between a nerve fiber of one neuron and another neuron, muscle fiber or glial cell. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.
6 D3ZE55 (/IDA) O88689 (/IDA) Q14BM8 (/IDA) Q8CB45 (/IDA) Q91Y03 (/IDA) Q99PF4 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
4 A0A0B5JFG8 (/IDA) A0A2R8Q566 (/IDA) A9QUV5 (/IDA) F1QRP2 (/IDA)
Glutamatergic synapse GO:0098978
A synapse that uses glutamate as a neurotransmitter.
4 D3ZE55 (/IDA) E9PXF0 (/IDA) Q3UTP0 (/IDA) Q5HZI5 (/IDA)
Glutamatergic synapse GO:0098978
A synapse that uses glutamate as a neurotransmitter.
4 D3ZE55 (/IMP) E9PXF0 (/IMP) Q3UTP0 (/IMP) Q5HZI5 (/IMP)
Integral component of postsynaptic membrane GO:0099055
The component of the postsynaptic membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
4 D3ZE55 (/IDA) E9PXF0 (/IDA) Q3UTP0 (/IDA) Q5HZI5 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
3 B9EJ92 (/IDA) Q05C01 (/IDA) Q91Y17 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
3 Q6NXW8 (/ISS) Q91XY7 (/ISS) Q9Z1B0 (/ISS)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
3 Q9H251 (/NAS) Q9UN70 (/NAS) Q9UN71 (/NAS)
Growth cone GO:0030426
The migrating motile tip of a growing neuron projection, where actin accumulates, and the actin cytoskeleton is the most dynamic.
3 A0A0A6YY37 (/IDA) Q7TQF1 (/IDA) Q91XX8 (/IDA)
Postsynaptic membrane GO:0045211
A specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters cross the synaptic cleft and transmit the signal to the postsynaptic membrane.
3 Q14BM8 (/IDA) Q8CB45 (/IDA) Q91Y03 (/IDA)
Photoreceptor disc membrane GO:0097381
Stack of disc membranes located inside a photoreceptor outer segment, and containing densely packed molecules of photoreceptor proteins that traverse the lipid bilayer. Disc membranes arise as evaginations of the ciliary membrane during the development of the outer segment and may or may not remain contiguous with the ciliary membrane.
3 Q14BM8 (/IDA) Q8CB45 (/IDA) Q91Y03 (/IDA)
GABA-ergic synapse GO:0098982
A synapse that uses GABA as a neurotransmitter. These synapses are typically inhibitory.
3 E9PXF0 (/IDA) Q3UTP0 (/IDA) Q5HZI5 (/IDA)
GABA-ergic synapse GO:0098982
A synapse that uses GABA as a neurotransmitter. These synapses are typically inhibitory.
3 E9PXF0 (/IMP) Q3UTP0 (/IMP) Q5HZI5 (/IMP)
Integral component of presynaptic membrane GO:0099056
The component of the presynaptic membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
3 E9PXF0 (/IDA) Q3UTP0 (/IDA) Q5HZI5 (/IDA)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
2 Q767H8 (/TAS) Q767I5 (/TAS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 Q767H8 (/TAS) Q767I5 (/TAS)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 O95206 (/TAS) Q9NPG4 (/TAS)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
2 Q91XZ4 (/IDA) Q91Y13 (/IDA)
Cell-cell junction GO:0005911
A cell junction that forms a connection between two or more cells in a multicellular organism; excludes direct cytoplasmic junctions such as ring canals.
2 F7BJK1 (/TAS) Q91XX1 (/TAS)
Cilium GO:0005929
A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body.
2 F1QUS2 (/IDA) Q6QQE1 (/IDA)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
2 F1QUS2 (/ISS) Q6QQE1 (/ISS)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
2 Q9NPG4 (/HDA) Q9Y5G0 (/HDA)
Photoreceptor inner segment GO:0001917
The inner segment of a vertebrate photoreceptor containing mitochondria, ribosomes and membranes where opsin molecules are assembled and passed to be part of the outer segment discs.
1 Q99PF4 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 F7BJK1 (/ISO)
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
1 F7BJK1 (/ISO)
Centrosome GO:0005813
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
1 Q99PF4 (/IDA)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 Q8VHR0 (/NAS)
Cell junction GO:0030054
A cellular component that forms a specialized region of connection between two or more cells or between a cell and the extracellular matrix. At a cell junction, anchoring proteins extend through the plasma membrane to link cytoskeletal proteins in one cell to cytoskeletal proteins in neighboring cells or to proteins in the extracellular matrix.
1 F7BJK1 (/ISO)
Stereocilium GO:0032420
An actin-based protrusion from the apical surface of auditory and vestibular hair cells and of neuromast cells. These protrusions are supported by a bundle of cross-linked actin filaments (an actin cable), oriented such that the plus (barbed) ends are at the tip of the protrusion, capped by a tip complex which bridges to the plasma. Bundles of stereocilia act as mechanosensory organelles.
1 Q99PF4 (/IDA)
Stereocilium GO:0032420
An actin-based protrusion from the apical surface of auditory and vestibular hair cells and of neuromast cells. These protrusions are supported by a bundle of cross-linked actin filaments (an actin cable), oriented such that the plus (barbed) ends are at the tip of the protrusion, capped by a tip complex which bridges to the plasma. Bundles of stereocilia act as mechanosensory organelles.
1 Q9H251 (/ISS)
Stereocilium tip GO:0032426
A distinct compartment at the tip of a stereocilium, distal to the site of attachment to the apical cell surface. It consists of a dense matrix bridging the barbed ends of the stereocilium actin filaments with the overlying plasma membrane, is dynamic compared to the shaft, and is required for stereocilium elongation.
1 Q99PF4 (/IDA)
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
1 F7BJK1 (/ISO)
Cell-cell contact zone GO:0044291
Extended zone of intimate apposition between two cells containing one or more types of intercellular junctions, e.g., the intercalated disk of muscle.
1 A0A0A6YY37 (/IDA)
Apical part of cell GO:0045177
The region of a polarized cell that forms a tip or is distal to a base. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue.
1 P58365 (/IDA)
Apical part of cell GO:0045177
The region of a polarized cell that forms a tip or is distal to a base. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue.
1 Q99PF4 (/ISO)
Synapse GO:0045202
The junction between a nerve fiber of one neuron and another neuron, muscle fiber or glial cell. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.
1 Q7TSK3 (/ISO)
Kinocilium GO:0060091
A nonmotile primary cilium that is found at the apical surface of auditory receptor cells. The kinocilium is surrounded by actin-based stereocilia.
1 Q99PF4 (/IDA)
Cochlear hair cell ribbon synapse GO:0098683
A ribbon synpase of an auditory hair cell of the cochlear. These ribbon synapses contain spherical synaptic ribbons and lack and arciform density.
1 Q99PF4 (/IDA)
Photoreceptor ribbon synapse GO:0098684
A ribbon synapse between a retinal photoreceptor cell (rod or cone) and a retinal bipolar cell. These contain a plate-like synaptic ribbon.
1 Q99PF4 (/IDA)
Schaffer collateral - CA1 synapse GO:0098685
A synapse between the Schaffer collateral axon of a CA3 pyramidal cell and a CA1 pyramidal cell.
1 D3ZE55 (/EXP)
Schaffer collateral - CA1 synapse GO:0098685
A synapse between the Schaffer collateral axon of a CA3 pyramidal cell and a CA1 pyramidal cell.
1 Q7TSK3 (/ISO)
Glutamatergic synapse GO:0098978
A synapse that uses glutamate as a neurotransmitter.
1 Q7TSK3 (/ISO)
Integral component of postsynaptic membrane GO:0099055
The component of the postsynaptic membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 Q7TSK3 (/ISO)
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