The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Cadherins
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 103: protocadherin-18 isoform X2

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
5 A0A2R8RMH2 (/IPI) A9CPE6 (/IPI) F1QGL4 (/IPI) F8W3H1 (/IPI) Q8VHR0 (/IPI)
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
1 Q8VHR0 (/NAS)

There are 8 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules GO:0016339
The attachment of one cell to another cell via adhesion molecules that require the presence of calcium for the interaction.
4 A0A0B5JFG8 (/IMP) A0A2R8Q566 (/IMP) A9QUV5 (/IMP) F1QRP2 (/IMP)
Cell migration involved in gastrulation GO:0042074
The migration of individual cells within the blastocyst to help establish the multi-layered body plan of the organism (gastrulation). For example, the migration of cells from the surface to the interior of the embryo (ingression).
4 A0A0B5JFG8 (/IMP) A0A2R8Q566 (/IMP) A9QUV5 (/IMP) F1QRP2 (/IMP)
Neuron projection morphogenesis GO:0048812
The process in which the anatomical structures of a neuron projection are generated and organized. A neuron projection is any process extending from a neural cell, such as axons or dendrites.
4 A0A2R8RMH2 (/IMP) A9CPE6 (/IMP) F1QGL4 (/IMP) F8W3H1 (/IMP)
Epiboly involved in gastrulation with mouth forming second GO:0055113
The expansion of one cell sheet over other cells involved in deuterostomic gastrulation.
4 A0A0B5JFG8 (/IMP) A0A2R8Q566 (/IMP) A9QUV5 (/IMP) F1QRP2 (/IMP)
Brain development GO:0007420
The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
3 A7MB46 (/ISS) Q9HCL0 (/ISS) Q9HCL0 (/ISS)
Homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156
The attachment of a plasma membrane adhesion molecule in one cell to an identical molecule in an adjacent cell.
1 Q8VHR0 (/NAS)
Brain development GO:0007420
The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
1 Q8VHR0 (/IEP)
Calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules GO:0016339
The attachment of one cell to another cell via adhesion molecules that require the presence of calcium for the interaction.
1 Q8VHR0 (/ISO)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
4 A0A0B5JFG8 (/IDA) A0A2R8Q566 (/IDA) A9QUV5 (/IDA) F1QRP2 (/IDA)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 Q8VHR0 (/NAS)
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