The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Cell-cell fusogen EFF/AFF, domain 3
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: EFF-1A

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
2 G5EBM0 (/IDA) G5ECA1 (/IDA)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
1 G5ECA1 (/IPI)
Showing 1 to 2 of 2 entries

There are 14 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Syncytium formation by plasma membrane fusion GO:0000768
The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells.
2 G5EBM0 (/IDA) G5ECA1 (/IDA)
Syncytium formation by plasma membrane fusion GO:0000768
The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells.
2 G5EBM0 (/IGI) G5ECA1 (/IGI)
Syncytium formation by plasma membrane fusion GO:0000768
The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells.
2 G5EBM0 (/IMP) G5ECA1 (/IMP)
Morphogenesis of an epithelium GO:0002009
The process in which the anatomical structures of epithelia are generated and organized. An epithelium consists of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube.
2 G5EBM0 (/IMP) G5ECA1 (/IMP)
Multicellular organism development GO:0007275
The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
2 G5EBM0 (/IGI) G5ECA1 (/IGI)
Embryonic body morphogenesis GO:0010172
The process in which the anatomical structures of the embryonic soma are generated and organized.
2 G5EBM0 (/IMP) G5ECA1 (/IMP)
Oviposition GO:0018991
The deposition of eggs (either fertilized or not) upon a surface or into a medium such as water.
2 G5EBM0 (/IMP) G5ECA1 (/IMP)
Locomotion GO:0040011
Self-propelled movement of a cell or organism from one location to another.
2 G5EBM0 (/IMP) G5ECA1 (/IMP)
Vulval development GO:0040025
The process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult.
2 G5EBM0 (/IMP) G5ECA1 (/IMP)
Post-embryonic body morphogenesis GO:0040032
The process in which the anatomical structures of the post-embryonic soma are generated and organized.
2 G5EBM0 (/IMP) G5ECA1 (/IMP)
Showing 1 to 10 of 14 entries

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
2 G5EBM0 (/IDA) G5ECA1 (/IDA)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
2 G5EBM0 (/IDA) G5ECA1 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 G5ECA1 (/IDA)
Cell-cell contact zone GO:0044291
Extended zone of intimate apposition between two cells containing one or more types of intercellular junctions, e.g., the intercalated disk of muscle.
1 G5ECA1 (/IDA)
Showing 1 to 4 of 4 entries
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