The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.
The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.
The usher protein is rather large (from 86 to 100kDa) and seems to be mainly composed of membrane-spanning beta-sheets, a structure reminiscent of porins. Although the degree of sequence similarity of these proteins is not very high, they share a number of characteristics. One of these is the presence of two pairs of cysteines, the first one located in the N-terminal part and the second at the C-terminal extremity that are probably involved in disulphide bonds. The best conserved region is located in the central part of these proteins PMID:19380723,PMID:18485872.
PMID:7909802 PMID:7906265 PMID:7906046 PMID:19380723 PMID:18485872.
Structures | |
---|---|
Domains: | 5 |
Domain clusters (>95% seq id): | 2 |
Domain clusters (>35% seq id): | 2 |
Unique PDBs: | 3 |
Alignments | |
Structural Clusters (5A): | 1 |
Structural Clusters (9A): | 1 |
FunFam Clusters: | 5 |
Function | |
Unique EC: | |
Unique GO: | 12 |
Taxonomy | |
Unique Species: | 2090 |