CATH Superfamily 2.60.40.2150
Interleukin-17 receptor A/B, fibronectin-III-like domain 2
The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Interleukin-17 receptor A/B, fibronectin-III-like domain 2
".
FunFam 2: Interleukin 17 receptor A
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 3 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Signaling receptor binding GO:0005102
Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
|
1 | Q60943 (/IPI) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | Q96F46 (/IPI) |
|
Interleukin-17 receptor activity GO:0030368
Combining with any member of the interleukin-17 family of cytokines and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
|
1 | Q96F46 (/NAS) |
There are 14 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cell surface receptor signaling pathway GO:0007166
A series of molecular signals initiated by activation of a receptor on the surface of a cell. The pathway begins with binding of an extracellular ligand to a cell surface receptor, or for receptors that signal in the absence of a ligand, by ligand-withdrawal or the activity of a constitutively active receptor. The pathway ends with regulation of a downstream cellular process, e.g. transcription.
|
1 | Q96F46 (/NAS) |
|
Positive regulation of interleukin-23 production GO:0032747
Any process that activates or increases the frequency, rate, or extent of interleukin-23 production.
|
1 | Q96F46 (/IDA) |
|
Positive regulation of interleukin-23 production GO:0032747
Any process that activates or increases the frequency, rate, or extent of interleukin-23 production.
|
1 | Q60943 (/ISO) |
|
Positive regulation of inflammatory response GO:0050729
Any process that activates or increases the frequency, rate or extent of the inflammatory response.
|
1 | Q60943 (/IMP) |
|
Defense response to fungus GO:0050832
Reactions triggered in response to the presence of a fungus that act to protect the cell or organism.
|
1 | Q60943 (/IMP) |
|
Cellular response to cytokine stimulus GO:0071345
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus.
|
1 | D4A740 (/IDA) |
|
Cellular response to cytokine stimulus GO:0071345
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus.
|
1 | Q60943 (/ISO) |
|
Granulocyte chemotaxis GO:0071621
The movement of a granulocyte in response to an external stimulus.
|
1 | Q60943 (/IMP) |
|
Fibroblast activation GO:0072537
A change in the morphology or behavior of a fibroblast resulting from exposure to an activating factor such as a cellular or soluble ligand.
|
1 | Q96F46 (/IDA) |
|
Fibroblast activation GO:0072537
A change in the morphology or behavior of a fibroblast resulting from exposure to an activating factor such as a cellular or soluble ligand.
|
1 | Q60943 (/ISO) |
|
Interleukin-17-mediated signaling pathway GO:0097400
A series of molecular signals initiated by the binding of interleukin-17 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
1 | Q96F46 (/TAS) |
|
Positive regulation of cytokine production involved in inflammatory response GO:1900017
Any process that activates or increases the frequency, rate or extent of cytokine production involved in inflammatory response.
|
1 | Q60943 (/IGI) |
|
Positive regulation of interleukin-5 secretion GO:2000664
Any process that activates or increases the frequency, rate or extent of interleukin-5 secretion.
|
1 | Q60943 (/IMP) |
|
Positive regulation of interleukin-13 secretion GO:2000667
Any process that activates or increases the frequency, rate or extent of interleukin-13 secretion.
|
1 | Q60943 (/IMP) |
There are 3 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q60943 (/IDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q96F46 (/TAS) |
|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | Q96F46 (/NAS) |
