The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 6: Complement C3
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 12 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
5 | P01024 (/IPI) P01024 (/IPI) P01025 (/IPI) P01026 (/IPI) P01027 (/IPI) |
C5L2 anaphylatoxin chemotactic receptor binding GO:0031715
Interacting selectively and non-covalently with a C5L2 anaphylatoxin chemotactic receptor.
|
5 | P01025 (/ISS) P01026 (/ISS) P01027 (/ISS) P12387 (/ISS) Q2UVX4 (/ISS) |
Complement binding GO:0001848
Interacting selectively and non-covalently with any component or product of the complement cascade.
|
2 | P98093 (/IDA) Q98977 (/IDA) |
Antigen binding GO:0003823
Interacting selectively and non-covalently with an antigen, any substance which is capable of inducing a specific immune response and of reacting with the products of that response, the specific antibody or specifically sensitized T-lymphocytes, or both. Binding may counteract the biological activity of the antigen.
|
2 | P98093 (/IDA) Q98977 (/IDA) |
Signaling receptor binding GO:0005102
Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
|
2 | P01024 (/TAS) P01024 (/TAS) |
C5L2 anaphylatoxin chemotactic receptor binding GO:0031715
Interacting selectively and non-covalently with a C5L2 anaphylatoxin chemotactic receptor.
|
2 | P01024 (/IDA) P01024 (/IDA) |
(1->3)-beta-D-glucan binding GO:0001872
Interacting selectively and non-covalently with (1->3)-beta-D-glucans.
|
1 | P98093 (/IDA) |
Lipid binding GO:0008289
Interacting selectively and non-covalently with a lipid.
|
1 | P01026 (/IDA) |
Lipid binding GO:0008289
Interacting selectively and non-covalently with a lipid.
|
1 | P01027 (/ISO) |
C5L2 anaphylatoxin chemotactic receptor binding GO:0031715
Interacting selectively and non-covalently with a C5L2 anaphylatoxin chemotactic receptor.
|
1 | P01027 (/ISO) |
Showing 1 to 10 of 12 entries
There are 73 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Positive regulation of protein phosphorylation GO:0001934
Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.
|
5 | P01025 (/ISS) P01026 (/ISS) P01027 (/ISS) P12387 (/ISS) Q2UVX4 (/ISS) |
Positive regulation of glucose transmembrane transport GO:0010828
Any process that increases the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
5 | P01025 (/ISS) P01026 (/ISS) P01027 (/ISS) P12387 (/ISS) Q2UVX4 (/ISS) |
Regulation of triglyceride biosynthetic process GO:0010866
Any process that modulates the rate, frequency, or extent of triglyceride biosynthesis. Triglyceride biosynthesis is the collection of chemical reactions and pathways resulting in the formation of triglyceride, any triester of glycerol.
|
5 | P01025 (/ISS) P01026 (/ISS) P01027 (/ISS) P12387 (/ISS) Q2UVX4 (/ISS) |
Positive regulation of lipid storage GO:0010884
Any process that increases the rate, frequency or extent of lipid storage. Lipid storage is the accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development.
|
5 | P01025 (/ISS) P01026 (/ISS) P01027 (/ISS) P12387 (/ISS) Q2UVX4 (/ISS) |
Positive regulation of G protein-coupled receptor signaling pathway GO:0045745
Any process that activates or increases the frequency, rate or extent of G protein-coupled receptor signaling pathway activity.
|
5 | P01025 (/ISS) P01026 (/ISS) P01027 (/ISS) P12387 (/ISS) Q2UVX4 (/ISS) |
Complement activation GO:0006956
Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway.
|
4 | F1P587 (/TAS) P01024 (/TAS) P01024 (/TAS) Q90633 (/TAS) |
Regulation of complement activation GO:0030449
Any process that modulates the frequency, rate or extent of complement activation.
|
4 | F1P587 (/TAS) P01024 (/TAS) P01024 (/TAS) Q90633 (/TAS) |
Complement activation GO:0006956
Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway.
|
3 | P01024 (/IMP) P01024 (/IMP) P01027 (/IMP) |
Complement activation, alternative pathway GO:0006957
Any process involved in the activation of any of the steps of the alternative pathway of the complement cascade which allows for the direct killing of microbes and the regulation of other immune processes.
|
3 | P01024 (/TAS) P01024 (/TAS) Q90633 (/TAS) |
Positive regulation of protein phosphorylation GO:0001934
Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.
|
2 | P01024 (/IDA) P01024 (/IDA) |
Showing 1 to 10 of 73 entries
There are 13 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
4 | F1P587 (/TAS) P01024 (/TAS) P01024 (/TAS) Q90633 (/TAS) |
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
4 | P01024 (/IDA) P01024 (/IDA) P01026 (/IDA) Q90633 (/IDA) |
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
3 | P01024 (/HDA) P01024 (/HDA) P01027 (/HDA) |
Endoplasmic reticulum lumen GO:0005788
The volume enclosed by the membranes of the endoplasmic reticulum.
|
2 | P01024 (/TAS) P01024 (/TAS) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
2 | P01024 (/TAS) P01024 (/TAS) |
Secretory granule lumen GO:0034774
The volume enclosed by the membrane of a secretory granule.
|
2 | P01024 (/TAS) P01024 (/TAS) |
Azurophil granule lumen GO:0035578
The volume enclosed by the membrane of an azurophil granule, a primary lysosomal granule found in neutrophil granulocytes that contains a wide range of hydrolytic enzymes and is released into the extracellular fluid.
|
2 | P01024 (/TAS) P01024 (/TAS) |
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
2 | P01024 (/HDA) P01024 (/HDA) |
Blood microparticle GO:0072562
A phospholipid microvesicle that is derived from any of several cell types, such as platelets, blood cells, endothelial cells, or others, and contains membrane receptors as well as other proteins characteristic of the parental cell. Microparticles are heterogeneous in size, and are characterized as microvesicles free of nucleic acids.
|
2 | P01024 (/HDA) P01024 (/HDA) |
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
1 | P01027 (/ISO) |
Showing 1 to 10 of 13 entries